Báo cáo Y học: Group IID heparin-binding secretory phospholipase A2 is expressed in human colon carcinoma cells and human mast cells and up-regulated in mouse inﬂammatory tissues doc

... Analyses of group IID phospholipase A2 (Eur. J. Biochem. 269) 2707 Group IID heparin-binding secretory phospholipase A2 is expressed in human colon carcinoma cells and human mast cells and up-regulated ... thatthis isozyme is expressed in human colon carcinoma celllines and human mast cells as well as various mouse tissues. Importantly, the expression of sPLA2 -IID is regulated bothpositively and ... thatall mast cells distributed in human tissues express sPLA2- IID only, since mast cell phenotypes is crucially in uencedby tissue microenvironments [53,54]. Indeed, a recentimmunohistochemical...

Báo cáo y học: "The epidemiology of medical emergency contacts outside hospitals in Norway - a prospective population based study"

... the Index [1]. The Index is based onideas from the Criteria Based Dispatch system in the US[15], and was first published in 1994. Clinical symptoms,findings and situations are categorised into ... distribution, and reproduction in any medium, provided the original work is properly cited.emergencies outside hospitals in Norway. Emergencymedicine is not a formal speciality for doctors in Norway.Still, ... constituted 31%. This places emphasis onsome of the upcoming challenges in emergency care,both in the primary and the secondary health care sys-tem, namely an increasingly older population and there-fore...

Báo cáo y học: "A three-country comparison of psychotropic medication prevalence in youth"

... Dutch and 0.15% in US youth) and antiparkinsonian agents (0.01% in German and Dutch and 0.05% in US youth). Anxiolyticuse was greater in Dutch youth than in German and USyouth, respectively: 0.73% ... antipsychotics in youth aged 0–4 ranged from 0.13% in Italy [24] to 0.5% in the Netherlands [29]. Generally, these antipsychoticprevalence findings closely matched those of this study,indicating ... Baltimore, Maryland, USA, 2Department of Psychiatry, School of Medicine, University of Maryland, Baltimore, Maryland, USA, 3Departments of Psychiatry and Pediatrics, Johns Hopkins Medical Institutions,...

Báo cáo y học: "Clinical review: Treatment of new-onset atrial fibrillation in medical intensive care patients – a clinical framework"

... [21,22]. Interestingly, systemicinflammatory response syndrome and sepsis are alsoindependent risk factors [10,14]. A proinflammatory state, asmeasured by leucocytosis or monocyte activation, is associated ... morbidity In all patient categories, AF is associated with increasedmorbidity. This is reflected by the number of reportedsymptoms and by the days spent in the ICU and in thehospital. Haemodynamic ... that thisrisk reduction outweighs the increased bleeding risk in thesepatients. The proinflammatory state probably increases therisk for stroke and the risk for AF independently [136].DiscussionAlthough...

Báo cáo y học: "Placenta Percreta-Induced Uterine Rupture Diagnosed By Laparoscopy in the First Trimester"

... uterine wall, the fetal heart rate was 171 beats/min, and uterine contractions were absent. La-boratory analysis showed a hemoglobin level of 10.3 Ivyspring International Publisher Int. ... uterine rupture; laparoscopy Introduction Uterine rupture due to placenta percreta is very rare, with an incidence of 1 in 5,000 pregnant women [1]. It often occurs in patients with a history ... g/dl and an elevated white blood cell count of 17550 cells/ mm3. Because the pregnancy was intrauterine and not otherwise, our initial clinical impression was appendicitis; however, in the...

Báo cáo y học: "A Comparative Effectiveness Study of Bone Density Changes in Women Over 40 Following Three Bone Health Plans Containing Variations of the Same Novel Plant-sourced Calcium"

... (immunocytochemical analysis), DNA synthesis (4.0, 3.0 and 4.0 fold, re-spectively) and Ca2+ deposition (2.0, 1.0 and 4.0 fold, respectively) were significantly increased in AC treated cells ... (BMD) by ensuring that they are getting the recommended amounts of calcium and vitamin D3, and that supplementation may be helpful in meeting these nutritional goals. Based on findings in the ... [9-13] including the increasing use of SSRIs for the treatment of depression [14-17] and contraceptives [18]. Since intentional and unintentional weight loss typically depletes bone density [19-30]...

Báo cáo y học: " the Value of Serum Biomarkers (Bc1, Bc2, Bc3) in the Diagnosis of Early Breast Cancer"

... moderate staining com-pletely surrounding cytoplasmic membrane in at least 10% of invasive carcinoma cells or presence of mem-branous staining in less than 30% provided that the staining is intense ... be in the study and were between 18-75 years of age were included in the study. The patients were divided into three groups. Group 1: BC group, Group 2: Benign breast disease group, and Group ... Training and Research Hospital 1st Biochemistry Clinic 3. Dokuz Eylül University Institute of Oncology 4. İzmir Atatürk Training and Research Hospital 1st Pathology Clinic  Corresponding...

Báo cáo y học: " Factors affecting the long-term response to tacrolimus in renal transplant patients: Pharmacokinetic and pharmacogenetic approac"

... tacro-limus is mainly metabolized by CYP3A4 and CYP3A5 enzyme isotype. CYP3A5 polymorphisms seem to affect tacrolimus kinetics at a greater degree com-pared to CYP3A4 ones and thereby, these polymor-phisms ... (G6986A) polymorphism, lo-cated in intron 3, has been recognized as the most important CYP3A5 polymorphism. The alleles A and G are CYP3A5*1 and CYP3A5*3, respectively. Indi-viduals carrying at ... 7 and 9) and CYP3A5*1/*3 genotype gives 168-, 148-, 125- and 20- bp (lanes 4, 5, 8 and 10). CYP3A5*3/*3 genotype is not seen in this picture. The 20- bp band is not visible. Analysis on a 3.5%...

Báo cáo y học: " Autonomic Dysfunction Presenting as Postural Orthostatic Tachycardia Syndrome in Patients with Multiple Sclerosis"

... sclerosis (MS) is an autoimmune inflammatory de-myelinating disease of the central nervous system (CNS) that is a leading cause of disability in young adults. Autonomic dysfunction is commonly ... levels in any of these patients. Symptoms of Multiple Sclerosis Visual disturbances in the form of episodic blur-ring of vision were seen in 4/9(44%) patients. Sensory disturbances including ... orthostatic tachycardia syndrome (POTS) in patients suf-fering from MS. Methods: The patients were included for analysis in this study if they had POTS with either a prior history of MS or having developed...

Báo cáo y học: "Serum cholesterol concentration associated with aspirin esterase activity in older people: preliminary data"

... where two distinct aspirin hydrolysis pathways act: a spontaneous pH-dependent hydrolysis and an en-zymatic hydrolysis by plasma/serum and erythrocyte esterases (6). The circulating aspirin esterase ... activities are mainly due to butyrylcholinesterase (BChE, pseudocholinesterase) and, in part, to albumin (6). Because of higher aspirin esterase activity lead-ing to faster aspirin hydrolysis, the ... aspirin hydrolysis occurs in blood, there is a paucity of information in regards to circulating aspirin esterase activity in various physiological and pathological conditions. High aspirin esterase...

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