Báo cáo khoa học: "Automatic Analysis of Patient History Episodes in Bulgarian Hospital Discharge Letters" ppt

... for Computational Linguistics Automatic Analysis of Patient History Episodes in Bulgarian Hospital Discharge Letters Svetla Boytcheva State University of Library Studies and Information Technologies and ... temporal analysis of clinical narratives deal with discharge letters. This demo presents a prototype for automatic splitting of the Patient history into ep...

Ngày tải lên: 17/03/2014, 22:20

... that binding of the same porphyrin to jacalin is mediated by a combination of hydrogen bonding and nonpolar inter- actions, including aromatic stacking interactions between the phenyl rings of the ... the binding in the two cases are very different. Whereas bind ing of porphyrins to TCSL is associated with positive DS° values, which favor binding, interaction of porphyrins with MC...

Ngày tải lên: 19/02/2014, 16:20

... group of GHMP kinases in which proton transfer does not play a major role in the rate determining step of catalysis. That five of the 10 disease-causing mutations resulted in insoluble protein in ... 2003 homoserine kinase, proton transfer is unlikely to play a major role in the rate-determining step of catalysis. Several of the disease-causing mutations are not soluble fol...

Ngày tải lên: 08/03/2014, 02:20

... demonstrate that C-domains possess an in trinsic editing function for the incoming aminoacyl moiety [6]. By using aminoacyl-S-CoA as probes it was shown that the ®rst C-domain of the tyrocidine synthetase ... systems of gramicidin S (Grs), tyrocidin A (Tyc), s urfactin (Srf), lichenysin (Lic), bacitracin ( Bac), fengycin (Fen), ente ro- bactin (Ent), chloroeremomycin (Cep), pristinamyci...

Ngày tải lên: 17/03/2014, 11:20

... °Cor 22 °C), by using an alternative expression host {BL21(DE3)[pLysS]} or by including protease inhibi- tors in the solutions used during purification. Kinetic analysis of disease-causing mutations The ... generalized form of galactosemia) being the most affec- ted. None of the mutations results in a greater than threefold change in the Michaelis constant (K m ). Protein–protein...

Ngày tải lên: 23/03/2014, 11:20

... eluted using a linear gradient of 0–500 m M NaOAc in 0.1 M NaOH over 20 min and a flow rate of 1 mLÆmin )1 . Preparation of oligosaccharides O-Deacylation of LPS with hydrazine. O-Deacylation of LPS ... Countries engaged in global vaccination programs against H. in uenzae serotype b (Hib) experienced a rapid decline in diseases caused by Hib strains. In the UK, Hib infection...

Ngày tải lên: 23/03/2014, 21:20

... Regardless of dopamine treatment, overexpres- sion of a-synuclein significantly affected the levels of four proteins [stathmin 1, glutathione S-transferase (GST)p, Ran 1 binding protein and C1q binding ... suggested to be linked to early stages of PD pathogenesis [26]. Interestingly, in our model, dopamine induces an increase of the actin bundles regulator fascin 1 [27] and discord...

Ngày tải lên: 15/02/2014, 01:20

... kinetic analysis of these inhibiting or activating effects was either incomplete [22,36–39] or debatable [33,42]. In particular, reported results were interpreted in terms of an AAA site distinct ... observations obtained (Table 1). The binding of tyramine to D70G, in the presence of o-NPA, is weaker (9.1-fold) than binding to the wild-type enzyme, and induces an activating ef...

Ngày tải lên: 18/02/2014, 17:20

... cen- ters are inhibited for Q B reduction by binding of a DCMU molecule in the Q B pocket; the remaining PSII centers are unaffected. However, a saturating concen- tration of DCMU would inhibit completely ... FEBS 4773 of Q A – in PSII centers that are affected by the nonsatu- rating concentration of inhibitor [7,8]. The E m of Q A is raised in the presence of DCMU in the...

Ngày tải lên: 19/02/2014, 05:20

... comparative immunoblotting data, it was of interest to re-examine the fate of cals equestrin by studying the entire complement of key Ca 2+ -binding elements in dystrophin- deficient skeletal muscle ... for silver staining, hot Coomassie s taining, ÔStains-AllÕ labelling or immunoblotting. T he following running conditions were used: 60 m in at 1 00 V , 6 0 m in at 500 V, 60 min a...

Ngày tải lên: 19/02/2014, 16:20