... that can cause FA (FANCA, FANCB, FANCC,FANCD1, FANCD2, FANCE, FANCF, FANCG, FANCJ,FANCL and FANCM), all of which are involved in the repair of DNA damage by homologous recombination (FANCD1 ... significantly to ourunderstanding of the TGF-β/Smad4 pathway in the development of pancreatic cancer [58–60].Pancreas development and how this hascontributed to our advancedunderstanding of pancreatic ... with high risk of pancreatic cancer and melanoma in the absence of the melanocytic nevi typical of FAMMM [82,83]; mixed melanoma and pancreatic cancerfamilies with germline mutations of INK4ap16are...