Báo cáo khoa học: "SEHANTICS OF TEHPORAL QUERIES AND TEHPORAL DATA" pot

... [3]. TRPM4b is a member of the family of melastatin- related transmembrane receptor potential channels. The eight members of this family differ largely in their ion selectivity and mode of activation [4]. ... Fig. 2A,B). Generation of HEK-293 clones with stable expression of TRPM4b To investigate the effect of TRPM4b expression on Ca 2+ entry and changes of the transmembra...

Ngày tải lên: 23/03/2014, 09:21

... support queries of this type. The second type of query asks about the state -of- the-world on a given date (Query 4) or during an interval of time (Query 5). Understanding and answering these queries ... variety of temporal queries. Based on this analysis, a computational model is described that satisfies many of the requirements for understanding and answering time...

Ngày tải lên: 17/03/2014, 19:21

... of InsP 6 to PhyAsr (Table 1). Given the absence of structural changes as a function of ionic strength and ligand binding, the effect of ionic strength on catalytic activity is probably not of ... move- ment of the P-loop in PhyAsr is due to oxidation of the catalytic cysteine, we oxidized crystals of PhyAsr Table 1. Effect of ionic strength on the hydrolysis of InsP 6 b...

Ngày tải lên: 18/02/2014, 18:20

... Sedla ´ c ˇ ek 3 and Jindr ˇ ich Has ˇ ek 1 1 Institute of Macromolecular Chemistry, 2 Institute of Organic Chemistry and Biochemistry and 3 Institute of Molecular Genetics, Academy of Sciences of the ... alternative positions of phenylalanine rings a re formed in concert with the alternative positions of S d and C c of Met46 and Met146 (from neighbouring protease di...

Ngày tải lên: 19/02/2014, 16:20

... action of EPA and DHA (Eur. J. Biochem. 271) 4465 Modulation of cyclin D1 synthesis and hyperphosphorylation of Rb by n-3 and n-6 PUFAs Induction of cyclin D1 is one of the e arliest effects of mitogenic ... contribute to the modu- lation of egr-1 gene expression (Fig. 4B). Effects of n-3 and n-6 PUFAs on the synthesis of caveolin-1 and caveolin-3 and on the loca...

Ngày tải lên: 19/02/2014, 16:20

... to learn thou- sands of Chinese characters. The official agents in Taiwan and China, respectively, chose 5401 and 3755 characters as important basic characters in national standards. Consequently, ... e.g., “賣” and “讀” are pronounced as /mai4/ and /du2/, respectively. In contrast, the pro- nunciations of “匋”, “淘”, “陶”, and “啕 ” are /tao2/. Pronunciations of specifi...

Ngày tải lên: 19/02/2014, 19:20

... consisting of the CSN, the 26S pro- teasome and cullin-based Ub ligases. Permanent expression of a chimerical subunit (Flag-CSN2-Rpn6) consisting of the N-terminal 343 amino acids of CSN2 and of the ... role of the PCI domain of CSN2 for complex formation and consequences of permanently overex- pressed CSN2 for the stability of p53 and c-Jun. The CSN interacts direct...

Ngày tải lên: 20/02/2014, 01:20

... Institute of Science and Technology, Ishikawa, Japan; 2 Department of Bioscience, School of Science and Technology, Kwansei Gakuin University, Hyogo, Japan; 3 Department of Synthetic Chemistry and ... T m of lysozyme was 77.3 °C in the absence of additives. The addition of 100 m M polyamines and Arg slightly increased the T m of lysozyme by  1 °Cand0.5°C, respectively...

Ngày tải lên: 20/02/2014, 02:21

... Program of the Office of the Director of NIH and by AIDS FIRCA Grant TW01001. The contents of this publication do not necessarily reflect the views or policies of the Department of Health and Human ... appropriate residues of enzyme and Fig. 1. Sequence around the NC/p1 and p1/p6 cleavage sites in HIV-1. The sequence of HIV-1 IIIB , a member of the B subtype, is shown....

Ngày tải lên: 21/02/2014, 03:20

... Frequency of Request types Since most of each dialogue consisted of the making of requests, the first analysis examined the frequency of the various kinds of requests in the corpus of five ... by the National Institute of Education under contract US-NIE-C-400-76-0116 to the Center for the Study of Reading of the University of Illinois and Bolt, Beranek and New...

Ngày tải lên: 21/02/2014, 20:20