... that CDO alone did not increase the extent of staining. However, in cells that had been cocultured with CDO and a cytotoxic drug, staining was significantly increased, indicating the presence of ... this protein, as seen in HCT116 cells, resulted in the absence of enhanced cell growth inhibition. The central role of p21 waf1 in mediating senescence is currently being investigated in...
Ngày tải lên: 07/03/2014, 15:20
... & Norvig, 1995). 3 Training Method 3.1 General Setting Our training set I consists of candidate inferences from the parse trees in the training data. From each training inference i ∈ I we generate ... regularization penalty by decreasing λ (Steps 1.6 and 1.7) and continue training. In this way, instead of choosing the best λ heuristically, we can optimize it during a single training r...
Ngày tải lên: 08/03/2014, 02:21
Báo cáo khoa học: Enzymes in organic media Forms, functions and applications potx
... subtilisin in the presence of 98% (w/w) of KCl was tentatively explained by either rigid salt structure protecting the enzyme in organic solvents or polar environment of salt helping in maintaining ... in enzymology. Lyophilization involves [28,33] (a) initial freezing, (b) primary drying (in which ice separated from the protein phase is removed by sublimat- ion) and (c) secondary dr...
Ngày tải lên: 16/03/2014, 16:20
Báo cáo khoa học: "Lexicalization in Crosslinguistic Probabilistic Parsing: The Case of French" potx
... Introduction This paper brings together two strands of research that have recently emerged in the field of probabilis- tic parsing: crosslinguistic parsing and lexicalized parsing. Interest in parsing models ... vary considerably in size: our FTB training set was about 8,500 sentences large, while the standard training set for the PTB is about 40,000 sentences in size, and the Negra tr...
Ngày tải lên: 17/03/2014, 05:20
Báo cáo khoa học: Dynamics in electron transfer protein complexes potx
... Tight-binding inhibition of angiogenin and ribonuclease-A by placen- tal ribonuclease inhibitor. Biochemistry 28, 225–230. 2 Janin J (2000) Kinetics and thermodynamics of protein– protein interactions. ... cytochrome c and bovine cytochrome b 5 predicted that the two proteins would dock essentially through a single binding domain but not in a single conformation [64]. Volkov et al. [69] hav...
Ngày tải lên: 22/03/2014, 16:20
Báo cáo khoa học: Alterations in the photoactivation pathway of rhodopsin mutants associated with retinitis pigmentosa potx
... transducin. J Biol Chem 263, 2119–2122. 48 Liu X, Garriga P & Khorana HG (1996) Structure and function in rhodopsin: correct folding and misfolding in two point mutants in the intradiscal domain ... HG (1997) Struc- ture and function in rhodopsin: packing of the helices in the transmembrane domain and folding to a tertiary structure in the intradiscal domain are coupled. Proc...
Ngày tải lên: 22/03/2014, 16:20
Báo cáo khoa học: The influence of cholesterol on the interaction of HIV gp41 membrane proximal region-derived peptides with lipid bilayers potx
... ectodomain MPR may have a very specific function in viral fusion through the concerted and combined action of cholesterol-binding and non-cholesterol-binding domains (i.e. domains corresponding to ... several membrane-binding motifs or by the particular dispo- sition of key residues in the context of long peptides or even in the context of the full protein. Bearing this in mind, a MPRP...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: Differences in substrate specificities between cysteine protease CPB isoforms of Leishmania mexicana are mediated by a few amino acid changes potx
... specificity of a recombinant cysteine proteinase, CPB, of Leishmania mexicana compared with cruzain, human cathepsin L and papain using substrates containing non-natural basic amino acids. Eur. J. ... peptidase upon transfer into the endoplasmic reticu- lum,a106aminoacidpro-region,a218aminoacidmature domain that includes the active site, and a C-terminal domain of either 16 or 100 amino acids...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: "Topics in Statistical Machine Translation" potx
Ngày tải lên: 23/03/2014, 17:20