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Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx

Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx

Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx

... Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice using in vivo 13 C NMR measurements of hepatic carbohydrate metabolism In- Young Choi1, Chaodong ... liverLabel incorporation into the glycogen C1 reflects glycogensynthesis via the direct pathway (glucose glucose- 6-phos-phatefiglycogen), whereas label incorporation into the glycogen C6 reflects activity ... resonancedue to label scrambling from pyruvate carboxylase/phos-phoenolpyruvate carboxykinase activity (Ôpyruvate recyc-lingÕ), the intensity of glycogen C4 was compared to the sum of the C2 , C3 ,...
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Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&

... over the course of the study. At baseline, mostcaregivers indicated inconsistency in their child's behavioracross the day in contrast to endpoint where the majorityreported consistency in ... with the efficacy of the study medi-cation on their child's attention. The majority of caregiv-ers (93.1%) indicated a high level of satisfaction with the duration of effect of the study ... endpoint. Improvement in compliance mayreflect increasing capacity to establish a routine of patchadministration with time, although noncompliance isoften underestimated in any clinical trial.Improvements...
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Báo cáo y học: "Grb2-associated binder 1 polymorphism was associated with the risk of Helicobactor pylori infection and gastric atrophy"

... development of gastric atrophy and cancer [2,3]. CagA/ src homology 2 domain-containing protein tyrosine phosphatase-2 (SHP-2) interaction elicits cellular changes that increase the risk of carcinogenesis ... Research on Special Priority Areas of Cancer from the Ministry of Education, Culture, Sports, Science and Technology of Japan. Conflicts of interest The authors have declared that no conflict of ... atrophy and cancer. This study investigated the associations of Grb2 associated binder 1 (Gab1) polymorphism and the combination of PTPN11 gene encoding src homology 2 domain-containing protein...
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Tài liệu Báo cáo Y học: Bivalent cations and amino-acid composition contribute to the thermostability of Bacillus licheniformis xylose isomerase doc

Tài liệu Báo cáo Y học: Bivalent cations and amino-acid composition contribute to the thermostability of Bacillus licheniformis xylose isomerase doc

... temperature) containing1mM CoCl2and 1 M glucose at 60 8C for 20 min The reaction was stopped by transferring the tubes to an ice bath. The amount of fructose produced was determined by the cysteine/carbazole/sulfuric ... (XIs) (EC 5.3.1.5), whichcatalyze the isomerization of D-xylose to D-xylulose in vivo, are used for the conversion of D -glucose into D -fructose for the production of high -fructose corn syrup [15]. ... (Co2þ,Mn2þ,orMg2þ)best activates BLXI on glucose and on xylose, the apoenzyme activity was tested on both sugars in the presence of increasing concentrations of each cation (in the chloride form; Fig. 4). In the...
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Báo cáo Y học: Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors potx

Báo cáo Y học: Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors potx

... here) increased the binding of eIF4E toeIF4G. In their case, however, binding of eIF4E to 4E-BP1was decreased, which is more in line with the expectedreciprocal effects on the binding of these ... translation in mammalian cellsinvolves the regulation of a range of components of the translational machinery, principally by changes in theirphosphorylation, leading to modulation of their activities ... important to consider their effectson protein synthesis when studying the effects of thesestress conditions on cell physiology. Other agents thatinhibit protein synthesis (such as cycloheximide...
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Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-specific protein over-expressed in Escherichia coli pptx

Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-specific protein over-expressed in Escherichia coli pptx

... properfolding or of increased solubility of the protein of interest.We propose that the success of fusion protein systemsshould be ascertained only once the protein of interest hasbeen cleaved off and ... that the fusion proteins werelabile and only partially soluble in five of the constructsresulting in very poor yields. Intriguingly, in the sixth con-struct, the yield of soluble fusion protein ... protein quality between Pfg27Aand the rest of the constructs was retained. Therefore, the differing proteinsolubilities were inherent in the constructs and could not bemodulated by varying the...
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Báo cáo Y học: Amphibian peptides that inhibit neuronal nitric oxide synthase The isolation of lesueurin from the skin secretion of the Australian Stony Creek Frog Litoria lesueuri docx

Báo cáo Y học: Amphibian peptides that inhibit neuronal nitric oxide synthase The isolation of lesueurin from the skin secretion of the Australian Stony Creek Frog Litoria lesueuri docx

... number of other enzymes including calcineurin. If the active amphibian pep tides are i ndeed interacting withCa2+calmodulin, they should also inhibit the activity of calcineurin. The four model ... Ca2+calmodulin, the inhibition dropped by  50% in each case. In addition,these peptides also inhibit the activity of calcineurin, anotherenzyme that requires the presence of the regulatory proteinCa2+calmodulin. ... aturallesueurin by e lectrospray mass spectrometry, and HPLC.Bioactivity assaysAntimicrobial testing. Synthetic lesueurin was t ested forantibiotic activity by the M icrobiology D epartment o f the Institute...
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 Báo cáo y học:

Báo cáo y học: "he Association Among Lipoprotein-associated Phospholipase A2 Levels, Total Antioxidant Capacity and Arousal in Male Patients with OSA"

... Research Hospital, Konya/ Turkey. 2. Department of Cardiology, Meram Medical Faculty, Selcuk University, Konya, Turkey. 3. Department of Biochemistry, Meram Medical Faculty, Selcuk University, ... Synchron Clinical System (Beckman Coulter, USA) automated clinical chemistry analyzer. The PLAC test is a turbidimetric immunoassay using two highly specific monoclonal antibodies against Lp-PLA2. ... Arousal-induced tachycardia, which generally corresponds to periods of high cardiac pre- and after-load and reduced myocardial oxygen de-livery at the termination of respiratory events, may provide...
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Báo cáo y học: "Clinical Symptoms Associated with Asystolic or Bradycardic Responses on Implantable Loop Recorder Monitoring in Patients with Recurrent Syncope"

... on ophthalmoscopy, with early hyopofluorescence and late staining on fluorescein angiography (FA). Inac-tive chorioretinal lesions typically are partially atro-phic and partially pigmented ... lesions, in the form of hy-pofluorescent spots, than those appreciated clinically or by FA. Other ocular manifestations of WNV infection include anterior uveitis, retinal vasculitis, optic neuri-tis, ... typical multifocal chorioretinitis, frequently asymptomatic, is the most common ocular manifesta-tion of WNV infection (80%).2 Active chorioretinal lesions appear as circular, deep, creamy...
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Báo cáo y học:

Báo cáo y học: "Clinical Symptoms Associated with Asystolic or Bradycardic Responses on Implantable Loop Recorder Monitoring in Patients with Recurrent Syncope"

... Duration of syncope: The duration of syncope was determined from the loss of consciousness to full recovery of consciousness. The duration also included the postictal confusion if it was a convulsive ... episodes of syncope. Patients were included in the study if they had either syncope or symptoms during monitoring which resembled the index syncope episode that lead to evaluation. Patients included ... frequently than are tachycardiac ones [13- 15]. The clinical symptoms most predictive of significant bradycardic events (such as prolonged sinus pauses or complete heart block) re-corded during...
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