Báo cáo Y học: Early growth response-1 gene (Egr-1 ) promoter induction by ionizing radiation in U87 malignant glioma cells in vitro pot
... elements in the hum an Egr-1 gene promoter. Rheumatol. Int. 18 , 207±214. 346 R. G. Meyer et al. (Eur. J. Biochem. 26 9) Ó FEBS 2002 Early growth response-1 gene ( Egr-1 ) promoter induction by ionizing ... Egr-1 promoter can be induced by a single dose of 4 Gy. The data presented indicate that radiation induction of the Egr-1 promoter is at least in p...
Ngày tải lên: 17/03/2014, 17:20
... Berlin, Germany; 2 Humboldt University Berlin, Institute of Biology, Theoretical Biophysics, Berlin, Germany; 3 Humboldt University Berlin, Medical Faculty (Charite ´ ), Institute of Biochemistry, ... 1.2.1.1 2); enolase (EC 4.2.1.1 1); alcohol dehydrogenase (EC 1.1.1. 1); pyruvate decarboxylase isozyme 1, 2, and 3 (EC 4.1.1. 1); aldehyde dehydrogenase (NAD(P) +) (EC 1.2.1. 5)...
Ngày tải lên: 17/03/2014, 10:20
... and ultimately abolished, the increase in c-myc gene expression elicited by PMA in serum-free cells. These results suggest that inhibition of MEK/ERK signaling by NAMI-A may have an important role in modulating ... to a scintillation vial. The radioactivity was determined by liquid scintillation counting. Determination of c- myc gene expression by RT-PCR analysis Serum-star...
Ngày tải lên: 21/02/2014, 01:21
Báo cáo y học: "Emulsified Isoflurane Preconditioning Reduces Lung Injury Induced By Hepatic Ischemia/Reperfusion in Rats"
... (v/v) manufac- tured by Huarui Pharmacy, Ltd (Wuxi, China) ac- cording to the procedures described previously 16,17 , was kindly bestowed by Prof. Jin Liu from the Labor- atory of Anesthesiology ... followed by reperfusion injury is asso- ciated with a number of clinical disorders, including systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS) an...
Ngày tải lên: 25/10/2012, 11:00
Báo cáo y học: "A cyclic-RGD-BioShuttle functionalized with TMZ by DARinv “Click Chemistry” targeted to αvβ3 integrin for therapy"
... Procedures Synthesis of the RGD-BioShuttle Derivatization of temozolomide N-(2-Aminopropyl)-4-(6-(pyrimidine-2-yl)-1,2,4,5-tetrazine-3-yl)be nzamide 4 4-(6-(Pyrimidine-2-yl)-1,4-dihydro-1,2,4,5-tetrazi ne-3-yl)benzoic ... o-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid chloride 7 result in the product 3-Methyl-4-ox o-N-(3-(4-(6-(pyrimidine-2 -y l) -1,2,4,5-tetrazin-3 -...
Ngày tải lên: 25/10/2012, 11:40
Báo cáo y học: "Comparison between single antiplatelet therapy and combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with antiphospholipid syndrome"
... (aspirin) and single anticoagulant (warfarin) therapy. Our results indicate that combination therapy may be more effective in APS-related ischemic stroke. Key words: antiphospholipid syndrome, ... 3. 0) with or without low-dose aspirin (75 mg/day) was significantly more effective than low-intensity war- farin (INR under 3. 0) with or without low-dose aspi- rin, or treatment with...
Ngày tải lên: 26/10/2012, 09:48
Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
... lineages. Keywords: a s1 -casein gene; allelic recombination; genetic polymorphism; g oat milk. Caseins comprise the main protein fraction of ruminant milk. They are encoded by four tightly linked ... diversity can arise from multiple pathways, including shuffling of polymorphic sequences generated by point mutations, through interallelic recombi- nation events. Fig. 9. Phylogeny proposed...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: Functional studies of the Synechocystis phycobilisomes organization by high performance liquid chromatography on line with a mass spectrometer docx
... phycocyanin to phycoerythrin in rods of certain phycobilisomes to improve light harvesting in changing habitats [1]. Thus in Synechocystis where phycoerythrin is not present, visible light may ... has phycobilisomes that are affected by the environment in diverse ways [2]. In general the macrostructure of phyco- bilisomes consists of a core (constituted by allophycocyanin) surro...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: Formation of conjugated D11 D13-double bonds by D12-linoleic acid (1,4)-acyl-lipid-desaturase in pomegranate seeds doc
... here by heterologous expression in yeast cells the enzyme PuFADX converts linoleic acid into another conjugated linolenic acid deri- vative (Fig. 5). In contrast to all other yet known (1, 4)- acyl- lipid-desaturases, ... yeast strain INVSc1 TM (Invitrogen, Carlsbad, USA) by lithium acetate [17]. Individual colonies of cell were then grown overnight at 30 °C in SD media lackin...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: Role of conserved residues within helices IV and VIII of the oxaloacetate decarboxylase b subunit in the energy coupling mechanism of the Na+ pump ppt
... hydroxyl side chain of tyrosine 229. This displacement may be facilitated involving by R389 through lowering the pK of the tyrosine hydroxyl group. The proton is delivered to the carboxybiotin ... serine hydroxyl and an aspartic acid, these experiments argue strongly against an acidic function of the serine hydroxyl; (d) upon replacing serine by alanine the enzyme remains reasonably activ...
Ngày tải lên: 08/03/2014, 23:20