... modify the conformation of the protein but abolish the ribosome- inactivating activity of a-sarcin. In addition, the loss of the positive charge at that position produces dramatic changes on the interaction ... Glu58 as the general base during the first step of the reaction. The hydrolysis of the cyclic derivative is performed by the same groups, but their r...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo Y học: Guanosine diphosphate-4-keto-6-deoxy-D-mannose reductase in the pathway for the synthesis of GDP-6-deoxy-D-talose in Actinobacillus actinomycetemcomitans potx
... respectively) to the proteins enco- ded by ORFs in the clusters responsible for synthesizing the SPAs in other serotypes of A. actinomycetemcomitans. The biosynthetic pathway for GDP-6-deoxy- D -talose, Fig. ... GDP-4-keto-6-deoxy- D -mannose reductase and the stereoselectivity of the reduction deter- mines the direction of synthesis of these two 6-deoxyhe...
Ngày tải lên: 17/03/2014, 10:20
... Frequency of the MTHFR genotypes and the result of the Chi square testing in the different studied groups. Showing the frequency and the results of the cross tabulation of the T allele and the different ... significant increase in tHcy in the TT genotype individuals in the different groups. This finding supports more the lack of association between...
Ngày tải lên: 03/11/2012, 09:49
Báo cáo y học: "Teaching child and adolescent psychiatry to undergraduate medical students - A survey in German-speaking countries"
... organization of topics to be taught. A limitation of the present study is the lack of information on the number of CAP staff and how many students they teach. In the review by Sawyer et al. on teaching ... [16], the inclusion of questions on CAP in final medical examinationsisessential.Inthe European survey [3], 86% of the departments had an examinationinCAP.Grades...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: "Emulsified Isoflurane Preconditioning Reduces Lung Injury Induced By Hepatic Ischemia/Reperfusion in Rats"
... Emulsified isoflurane preconditioning markedly attenuated hepatic I/R-induced lung injury in rats, which may be hopefully applied to the clinical treatment of organ injury caused by hepatic surgery, ... incubated for 30 min with intermittent stirring. The suspension was centrifuged at 15,000g for 10min at 4℃, and the protein concentration was determined by Coomassie blue dye-...
Ngày tải lên: 25/10/2012, 11:00
Báo cáo y học: " Helicobacter pylori induces mitochondrial DNA mutation and reactive oxygen species level in AGS cells"
... stimulate the pro- duction of reactive oxygen metabolite in the antral mucosa in vivo [23]. Hp can induce the production of pro-inflammatory cytokines from gastric epithelial cells resulting in the ... mtDNA resulting in abnormality in ATP produc- tion. Therefore, the amount of ATP was further de- termined aiming to indirectly detect the cell viability and the...
Ngày tải lên: 25/10/2012, 11:18
Báo cáo y học: "Maitake Mushroom Extracts Ameliorate Progressive Hypertension and Other Chronic Metabolic Perturbations in Aging Female Rats"
... hydro- lyzed by ACE to furylacryloylphenylalanine (FAP) and glycylglycine. Hydrolysis of FAPGG results in a decreased absorbency at 340 nm. Serum ACE activity was determined by comparing the ... minutes post injection. The area under the curve was used to estimate activity of the NO system with an increase in SBP connoting augmented system activity. Cytokine Assay: Var...
Ngày tải lên: 26/10/2012, 08:57
Báo cáo Y học: A Ca2+/CaM-dependent kinase from pea is stress regulated and in vitro phosphorylates a protein that binds to AtCaM5 promoter ppt
... ([Ca 2+ ] cyt ) is transduced by two main pathways, one involving CaM and CaM-related proteins, and the other involving CDPKs. Both of these pathways cross-talk at various points in the signaling cascade ... binding with DNA [27,53–55]. We have found that the binding of p40 is dependent on the dephosphorylation status of the protein and the binding is fully abolished once...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo Y học: Human bile salt-stimulated lipase has a high frequency of size variation due to a hypervariable region in exon 11 pot
... fat-soluble vitamin esters and cholesterol esters in the small intestine. In some species, including humans, the gene is also expressed in the lactating mammary gland and the resulting protein is a constituent of ... con- ®rming a different sequence of t he tail. The f unction of the tail has previously been discussed in the literature. Deletion of the tail by...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo Y học: Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells pptx
... brought in proximity with the ZAP70 tyrosine kinase, the main phosphate-donor and thus activator, of these signaling proteins. These interactions are then of importance for the activation of both the ... associate with the Shb–PTB-Pro– GST fusion protein, containing both the PTB domain and two of the N-terminal proline-rich domains. This interac- tion was only slight...
Ngày tải lên: 24/03/2014, 04:21