Báo cáo Y học: Differential scanning calorimetric study of myosin subfragment 1 with tryptic cleavage at the N-terminal region of the heavy chain pdf

... results show that the N-terminal tryptic cleavage of the S1 heavy chain dramatically decreases the thermal stability of S1 and completely prevents the actin-induced conformational changes in the S1 molecule. ... about the properties of S1 modified by the N-terminal cleavage. This cleavage was found to accelerate the inactivation of the S1 ATPase upon mi...

Ngày tải lên: 17/03/2014, 10:20

... 11 .1 vs. glucose Table 1: Characteristics of patients in normoglycaemia and hyperglycaemia group at initiation of follow-up All patients (N = 1, 029) Patients with hyperglycaemia (N = 360) Patients ... indexes. During the five years of follow-up, 10 2 (15 .2%) patients in the normoglycaemia group and 66 (18 .3%) patients in the hyperglycaemia group died. There were 15...

Ngày tải lên: 25/10/2012, 10:02

... ranges at baseline with those that became abnor- mal or unacceptable by the end of the study. In all three groups and sub-groups, none of the normal scores were abnormal by the end of the study. ... test and to have the study components explained to them prior to enrolling for the study. Of these, 15 8 agreed to par- ticipate, 12 5 of whom ultimately com...

Ngày tải lên: 25/10/2012, 11:10

... 2300 -17 66/ 01) DLBCL man /19 61 #9 (# 12 12 -12 16/ 01) FL, stage I, preferentially small cells man /19 36 #10 (# 15 37 -15 39) DLBCL man /19 75 #13 (# 334-336/ 01) Nodular sclerotic HD man /19 71 #14 (# 2 218 - 2 219 /00) ... population of lymphoma h2 as driver; and vice versa, 2) the cDNA population of lymphoma h2 as tracer, and the cDNA population of lymphoma h1...

Ngày tải lên: 02/11/2012, 11:08

... likely mediated by activation of the MAPK pathway and that this response is substantially independent of the JAK/STAT pathway. DISCUSSION We have successfully expressed an active fusion protein of human ... including the STAT3 and the MAPK Fig. 6. STAT3 and MAPK activation by Hyper-CNTF in PC12 cells. PC12 cells were stimulated with medium alone, 20 ngÆmL )1 Hyper-IL- 6, 10...

Ngày tải lên: 22/02/2014, 07:20

... (20 01) ATP- independent fatty acyl-coenzyme A synthesis from phospholipid: coenzyme A-dependent transacylation activity toward lysopho- sphatidic acid catalyzed by acyl-coenzyme A: lysophosphatidic acid ... Release 1- Acyl-2-AA-GPC 0.495 ± 0.066 0.237 ± 0.070* )0.258 1- Alkyl-2-AA-GPC 1. 655 ± 0.224 0.550 ± 0.058* )1. 105 1- Alk -1- enyl-2-AA-GPC 0 .10 2 ± 0. 013 0 .19 1 ± 0 .14 1 +0.089...

Ngày tải lên: 22/02/2014, 07:20

... metabolism. The fermentation of organic compounds is associated with hydrogen evolution. The key enzyme hydrogenase, which is synthesized only after an anaerobic adaptation, catalyzes the reversible ... anaerobically adapted algae ( tester). The driver and t ester cDNAs w ere denatured separately for the first hybridization at 10 0 °Cfor 30 s and then incubated for 10 h at...

Ngày tải lên: 08/03/2014, 22:20

... days, and > 10 % after 4 days (Fig. 2A). The expression of hTERT was dramatically decreased after 1 day of treatment, indicating that the hTERT subunit was significantly corre- lated with the ... 2 days of treatment and 70% after 4 days. After 4 days of treatment with 10 0 ngÆmL )1 TPA, > 90% of the HL-60 cells became attached to the flask and developed dendr...

Ngày tải lên: 17/03/2014, 23:20

... case of Hb J Meerut in a Turkish male who is unrelated to the first family are described. In the present case a slight increase in the oxygen affinity of Hb J Meerut, relative to that of the ... electrophoresis at pH 8.6, and had same electrophoretic mobility with Hb A by citrate agar electrophoresis at pH 6.2 [6]. Modified chromatographic analysis of red cell lysat...

Ngày tải lên: 02/11/2012, 10:09

... affinity conformation asso ciated with the slow-inactivated state. This suggestion is supported by our study with Lqh-II, using both b inding and electro- physiological analyses [42] and the study of ... in the association rate. The binding of 12 5 I-labelled d-ACTX-Hv1a to rat brain syna- ptosomes is inhibited c ompetitively by classical ScaTxs and allosterically by breve...

Ngày tải lên: 08/03/2014, 16:20