Báo cáo Y học: Differential scanning calorimetric study of myosin subfragment 1 with tryptic cleavage at the N-terminal region of the heavy chain pdf
Báo cáo Y học: Differential scanning calorimetric study of myosin subfragment 1 with tryptic cleavage at the N-terminal region of the heavy chain pdf
... resultsshow that the N-terminal tryptic cleavage of the S1 heavy chain dramatically decreases the thermal stability of S1 andcompletely prevents the actin-induced conformationalchanges in the S1 molecule. ... about the properties of S1 modified by the N-terminal cleavage. This cleavage was found toaccelerate the inactivation of the S1 ATPase upon mild heattreatment with the loss of the ability of nucleotides ... 21 26.5688 O. P. Nikolaeva et al. (Eur. J. Biochem. 269) Ó FEBS 2002 Differential scanning calorimetric study of myosin subfragment 1 with tryptic cleavage at the N-terminal region of the heavy...
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Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"
... 11 .1 vs. glucoseTable 1: Characteristics of patients in normoglycaemia and hyperglycaemia group at initiation of follow-upAll patients(N = 1, 029)Patients with hyperglycaemia(N = 360)Patients ... indexes.During the five years of follow-up, 10 2 (15 .2%) patientsin the normoglycaemia group and 66 (18 .3%) patients in the hyperglycaemia group died. There were 15 4 patientsin the normoglycaemia group ... other diagnoses 48 10 6all patients 19 3 398New IFG or IGT- sepsisa 18 18 2 .1 (95% CI 1. 3 to 4 .1) - ACSb 19 17 2.6 (95% CI 1. 4 to 4.6)- other diagnoses 10 14 1. 9 (95% CI 0.9 to 3.9)all patients...
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Báo cáo y học: "A Comparative Effectiveness Study of Bone Density Changes in Women Over 40 Following Three Bone Health Plans Containing Variations of the Same Novel Plant-sourced Calcium"
... ranges at baseline with those that became abnor-mal or unacceptable by the end of the study. In all three groups and sub-groups, none of the normal scores were abnormal by the end of the study. ... test and to have the study components explained to them prior to enrolling for the study. Of these, 15 8 agreed to par-ticipate, 12 5 of whom ultimately completed the study PP. For Plan 3, 80 adults ... supplementation. These increases occurred without adverse side effects. While the study also provides evidence of the benefit of adding the physi-cal activity and health literacy components, the data...
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Báo cáo y học: "Differential gene expression in HIV/SIV-associated and spontaneous lymphomas"
... 2300 -17 66/ 01) DLBCL man /19 61 #9 (# 12 12 -12 16/ 01) FL, stage I, preferentially small cells man /19 36 #10 (# 15 37 -15 39) DLBCL man /19 75 #13 (# 334-336/ 01) Nodular sclerotic HD man /19 71 #14 (# 2 218 -2 219 /00) ... population of lymphoma h2 as driver; and vice versa, 2) the cDNA population of lymphoma h2 as tracer, and the cDNA population of lymphoma h1 as driver. The cDNAs selected by the two-step differential ... libraries of lymphomas h1 and h2 were analyzed by dot blot hybridization with [32P]-labeled cDNA populations from SIV-associated monkey lymphomas and monkey B-lymphocytes. Those cDNAs whose hybridization...
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Tài liệu Báo cáo Y học: Differential response of neuronal cells to a fusion protein of ciliary neurotrophic factor/soluble CNTF-receptor and leukemia inhibitory factor pot
... likely mediated byactivation of the MAPK pathway and that this response issubstantially independent of the JAK/STAT pathway.DISCUSSIONWe have successfully expressed an active fusion protein of human ... including the STAT3 and the MAPKFig. 6. STAT3 and MAPK activation by Hyper-CNTF in PC12 cells.PC12 cells were stimulated with medium alone, 20 ngÆmL )1 Hyper-IL-6, 10 0 ngÆmL )1 NGF, 20 ngÆmL )1 Hyper-CNTF, ... activity was obtained with cytokine concen-trations of 5 10 pgÆmL )1 . Accordingly, Hyper-CNTF rep-resents a protein with greatly enhanced bioactivity requiringheterodimerization of the b-receptor...
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Tài liệu Báo cáo Y học: Differential effects of arachidonoyl trifluoromethyl ketone on arachidonic acid release and lipid mediator biosynthesis by human neutrophils pot
... (20 01) ATP-independent fatty acyl-coenzyme A synthesis from phospholipid:coenzyme A-dependent transacylation activity toward lysopho-sphatidic acid catalyzed by acyl-coenzyme A: lysophosphatidicacid ... Release 1- Acyl-2-AA-GPC 0.495 ± 0.066 0.237 ± 0.070* )0.258 1- Alkyl-2-AA-GPC 1. 655 ± 0.224 0.550 ± 0.058* )1. 105 1- Alk -1- enyl-2-AA-GPC 0 .10 2 ± 0. 013 0 .19 1 ± 0 .14 1 +0.089 1- Acyl-2-AA-GPI 1. 829 ± 0.0 41 ... resulting in the formation of 1- alk -1- enyl-2-lyso-GPE. Wykle and colleagues haveshown that 1- alk -1- enyl-2-lyso-GPE enhances PAF for-mation by a CoA-IT-dependent generation of lyso PAF[55].Thus,whilePLA2isotypes...
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Báo cáo Y học: Differential regulation of the Fe-hydrogenase during anaerobic adaptation in the green alga Chlamydomonas reinhardtii pot
... metabolism. The fermentation of organic compounds is associated with hydrogen evolution. The key enzyme hydrogenase, which issynthesized only after an anaerobic adaptation, catalyzes the reversible ... anaerobicallyadapted algae ( tester). The driver and t ester cDNAs w eredenatured separately for the first hybridization at 10 0 °Cfor30 s and then incubated for 10 h at 68 °C. For the secondhybridization, ... M.W.W. (19 90) The structure and mechanism of iron-hydrogenases. Biochim. Biophys. Acta 10 20, 11 5 14 5.8. Berkessel, A. & Thauer, R.K. (19 95) On the mechanism of catalysis by a metal-free hydrogenase...
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Báo cáo Y học: Differential regulation of telomerase activity by six telomerase subunits potx
... days, and> 10 % after 4 days (Fig. 2A). The expression of hTERTwas dramatically decreased after 1 day of treatment,indicating that the hTERT subunit was significantly corre-lated with the ... 2 days of treatment and 70% after 4 days. After4 days of treatment with 10 0 ngÆmL )1 TPA, > 90% of the HL-60 cells became attached to the flask and developeddendriform cytoplasm, indicating ... telomerasecomplex [14 16 ]. Greater expression of hTERT, but less of hTR or TEP1, has been reported to correlate with telomerase activity in cancer cells [17 ,18 ]. An association of telomerase activity with the...
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Báo cáo y học: "Hb J- Meerut [α 120 (H3) Ala -Glu (α1)] In A Turkish Male"
... case of Hb J Meerut in a Turkish male who is unrelated to the first family are described. In the present case a slight increase in the oxygen affinity of Hb J Meerut, relative to that of the ... electrophoresis at pH 8.6, and had same electrophoretic mobility with Hb A by citrate agar electrophoresis at pH 6.2 [6]. Modified chromatographic analysis of red cell lysate was done by HPLC using a cation ... is unrelated to the family with the same abnormal hemoglobin described previously from Turkey. 2. A CASE REPORT AND RESULTS The propositus was a healthy 34-year old male native of Isparta,...
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Báo cáo Y học: Variations in receptor site-3 on rat brain and insect sodium channels highlighted by binding of a funnel-web spider d-atracotoxin pdf
... affinity conformation asso ciated with the slow-inactivated state. This suggestion is supportedby our study with Lqh-II, using both b inding and electro-physiological analyses [42] and the study of ... in the association rate. The binding of 12 5I-labelled d-ACTX-Hv1a to rat brain syna-ptosomes is inhibited c ompetitively by classical ScaTxs andallosterically by brevetoxin -1, similar to ScaTx ... Bioc hem-istry 35, 10 215 10 222.32. K anner, B.I. (19 78) A ctive transport o f gamma-aminobutyric acidby membrane vesicles isolated from rat b rain. Biochemistry 17 , 12 07 12 11. 33. K rimm,...
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