Báo cáo Y học: The inhibitory region of troponin-I alters the ability of F-actin to interact with different segments of myosin pot
... interaction with myosin is the inhibitory region of TnI which on binding to actin renders the molecule unable to bind to the N-terminus of MLC1 and the myosin loop peptide and possibly other sites of interaction ... of the peptide. The arginine residues of the IP are located in the central portion of the region associated with inhibitory act...
Ngày tải lên: 17/03/2014, 10:20
... d b y loose closure of the dura and skin layers presum a b l y allows for expansion of the edematous brain into a durotomy “bag” under the loosely closed scalp without restriction by the ... requires that the craniectomy comes down to the floor of the middle cranial fossa, at the root of the zygoma; this ensures adequate lateral decompression of the...
Ngày tải lên: 25/10/2012, 11:40
... • the patient is not compliant, • partial weight bearing of the operated extremity cannot be tolerated, • the spacer is insufficiently fixated onto the proximal femur, • the size of the ... arthroplasty. A spacer fracture can be either symptomatic or asymptomatic depending on the fracture localisation. Symptomatic fractures (Figure 5) are usually the con- sequence...
Ngày tải lên: 26/10/2012, 09:53
Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx
... for the first time the results of a comparative study on the organic matrix extracted from the nacreous layer of the shell from the pearl oyster Pinctada maxima by two very different methods. The ... demineralization of the nacreous layer with hydrochloric acid [61]. The characterization of the proteins associated to this complex by amino acid analysis of t...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: BIGH3 (TGFBI) Arg124 mutations influence the amyloid conversion of related peptides in vitro Implications in the BIGH3-linked corneal dystrophies pptx
... decades of life and severely impair visual acuity in adulthood. Their therapy is restricted to keratopl- asty and phototherapeutic keratectomy by Excimer laser. Unfortunately, the benefits of these therapies ... were synthesized as described above. Their sequences were decided on the grounds of the results of the amyloid fibril experiments. BB1 was designed to interfere wit...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: Interallelic complementation provides genetic evidence for the multimeric organization of the Phycomyces blakesleeanus phytoene dehydrogenase doc
... via three enzymatic steps carried out by the enzymes phytoene synthase, phytoene dehydrogenase and lycopene cyclase. The enzyme phytoene dehydrogenase is able to introduce four dehydrogenations ... S andmann [39] found that the phytoene dehydrogenase activity was partially restored by treatment with T ween 40. Computer analysis of the Phyco- myces phytoene dehydrogenase deduced...
Ngày tải lên: 22/02/2014, 04:20
Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
... (France) and Montefalcone (Italy), respectively. Nevertheless, whatever the hypothesis retained, the existence of two ancestral allelic lineages seems to be the most likely scenario. Thus, interallelic ... comparisons of these sequences with those of previously characterized alleles have allowed the identification of additional poly- morphic sites, the arrangements (haplo...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: Mammalian HSP60 is quickly sorted into the mitochondria under conditions of dehydration docx
... sequence. Although the antibody against cytoplasmic HSP60 was recognized by both the cytoplasmic and the mitochondrial HSP60, an antibody against the signal sequence of HSP60 was recognized only by the cytoplasmic ... Newly synthesized HSP60 in the cytoplasm will be imported into the mitochondria under appropriate conditions. In the present study, we observed the import o...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Holliday junction binding and processing by the RuvA protein of Mycoplasma pneumoniae ppt
... resolvasome complex requires the binding of RuvA to one face of the junction and RuvC to the other [8,9]. Complexes formed by the loading of both RuvA and RuvC on a synthetic junction can be detected using ... resolution by RuvABC [12]. The importance of this structure is reflected in the high conservation of the sequences forming the pin in th e majority of bac...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: S-Decyl-glutathione nonspecifically stimulates the ATPase activity of the nucleotide-binding domains of the human multidrug resistance-associated protein, MRP1 (ABCC1) ppt
... as dodecyl-maltoside and S-decyl-glutathione (not shown). Thus, the stimulatory effect of S-decyl-glutathione or other surfactants on the ATPase activity of the MRP–NBDs seems to be related to micelle ... 3475 behaviour may result from different contacts within the full length MRP1 of the NBD(s) with other domains and/or the lipidic bilayer. The hydrolysis of ATP...
Ngày tải lên: 17/03/2014, 23:20