Báo cáo Y học: Prediction of temporal gene expression Metabolic optimization by re-distribution of enzyme activities ppt
... Prediction of temporal gene expression Metabolic optimization by re-distribution of enzyme activities Edda Klipp 1 , Reinhart Heinrich 2 and ... depletion of glucose is accompanied by concerted changes in the mRNA levels for most enzymes of the central metabolism of yeast resulting in down-regulation of glycolysis and up-regulation of the ... regulation; g...
Ngày tải lên: 17/03/2014, 10:20
... synthase, which uses 5-methyltetrahydrofolate as a carbon donor [6] . This donor is synthesized by the methylenetetrahydrofolate reductase (MTHFR) gene from 5,10-methylene-tetrahydrofolate [9,10]. Reduction ... tHcy has a positive effect on the hydroxyl methyl glutaryl -CoA synthase enzyme ( the rate limiting enzyme in cholesterol biosynthesis) and hence hypercholesterolaemia. Fu...
Ngày tải lên: 03/11/2012, 09:49
... model of interaction can be tested b y additional mutations, by solving the structure of some of the complexes or by other experimental means. CONCLUSIONS We have analysed the possibility of predicting ... the probability of correct predictions [P(x) in Table 1]. P(x) gives the accuracy of the prediction of the x class with respect to the overall amount of total predic...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo y học: "Bench-to-bedside review: The MET syndrome – the challenges of researching and adopting medical emergency teams"
... data [52-56]. Inherent within this type of evidence is the lack of rigour and generalisability. Furthermore, the magnitude of the effect of the MET may be influenced by institution-specific administrative ... the critically ill anywhere in the hospital The concept of rapid and early rescue is well established in various fields of medicine, especially in trauma, cardiology, and,...
Ngày tải lên: 25/10/2012, 10:35
Báo cáo y học: "Percutaneous laser disc decompression for thoracic disc disease: report of 10 cases"
... Mork 2,3 , Morgan Pyne 4 and Ryan A. Baker 4 1. Chief of Pain Medicine and Anesthesiology 2. Chief of Spine Surgery 3. MicroSpine, DeFuniak Springs, FL 32435, USA 4. University of South Florida ... recent sys- tematic review reported the published evidence to be of low quality (16). The authors identified only two studies by the same authors for inclusion, each over 10...
Ngày tải lên: 26/10/2012, 09:07
Tài liệu Báo cáo khoa học: Hsp105b upregulates hsp70 gene expression through signal transducer and activator of transcription-3 pdf
... significantly suppressed by the STAT3 siRNA but not by control siRNA (Fig. 4). These results further suggested that STAT3 mediates Hsp105b-induced expression of the hsp70 gene. STAT3 is activated by tyrosine ... expres- sion. STAT family proteins are present in a latent, mono- meric form in the cytoplasm, and are activated by specific tyrosine phosphorylation by JAK family mem-...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo Y học: Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA pdf
... groups are always introduced, one slowly by Dnmt3a or by de novo methylation catalyzed by Dnmt1 and the second one very fast. Therefore, this effect can only double the rate of DNA methylation, because every ... novo methylation of DNA [15]. Interestingly, the de novo activity of Dnmt1 is stimulated by binding of methylated DNA to an allosteric site located in the N-terminal d...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx
... Proline, hydroxyproline and hydroxylysine were examined at 254 nm by reverse-phase HPLC of their phenylisothiocarbamate derivatives [26], as reported previously [20]. The serine, threonine and tyrosine contents ... aliquot size, as proposed by Gold [30]. Calcium analysis Calcium analyses were performed after nitric acid hydrolysis of samples, by atomic absorption spectrophotometry,...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: BIGH3 (TGFBI) Arg124 mutations influence the amyloid conversion of related peptides in vitro Implications in the BIGH3-linked corneal dystrophies pptx
... [12] in a phenotypic variant of granular corneal dystrophy type 1 (GCD1), Arg124His (R124H) [1] in granular corneal dystrophy type 2 (GCD2, Avellino dystrophy) a mixed type of amyloid and granular ... was assessed by the dilution of 0.5 lmol of each peptide in 50 lL of distilled water and studied on day 1, day 3, day 7, and day 15. Congo red stain Pellets obtained by centrifugat...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: A novel, inducible, citral lyase purified from spores of Penicillium digitatum docx
... [31], respectively. Citral lyase is a monomeric enzyme of 30 kDa, which is approximately the monomeric size of these hydratase/aldolase enzymes. All of these enzymes exhibit more then 75% of their maximum ... standard. RESULTS Induction of citral lyase Initially, the reproducibility of the results was hindered by variations in the citral lyase activity of the P. digitatum sp...
Ngày tải lên: 21/02/2014, 01:21