Báo cáo khoa học: Reconstruction of the central carbon metabolism of Aspergillus niger pot
Báo cáo khoa học: Reconstruction of the central carbon metabolism of Aspergillus niger pot
... to the theoretically predicted properties [39]. Conclusions The reconstruction of the central carbon metabolism of A. niger presented here provides the first detailed descrip- tion of the central ... stoichiometric model. Ó FEBS 2003 Reconstruction of Aspergillus niger metabolism (Eur. J. Biochem. 270) 4253 Reconstruction of the central carbon m...
Ngày tải lên: 17/03/2014, 10:20
Tài liệu Báo cáo khoa học: Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina doc
... with the number EC 1.1.1.156. The properties of GLD2 are similar to those of the enzymes purified from A. niger [1] and A. nidulans [2]; that is, the enzyme catalyses the reversible reduction of ... therefore ampli- fied the open reading frame from the genomic DNA. We called the genes gld1 and gld2, respectively. Comparison of the cDNA of gld1 with the genome seq...
Ngày tải lên: 19/02/2014, 06:20
Báo cáo khoa học: Val216 decides the substrate specificity of a-glucosidase in Saccharomyces cerevisiae doc
... locates on the long loop region followed by Nb4, and the side chain of Val200 faces toward the inside of the c atalytic cleft [39]. Figure 4 shows the h ypothetical structure of the active site of S. ... because the steric hindrance between OG1 of Thr216 and O3¢ of maltose is canceled by the rotation of the s ide c hain of Thr216. The results indicate that...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: "Completing on the partial basis parses of ill-formed sentences of discourse information" docx
... parses with the application of our method, the heuristic rules were applied. In such cases the default rule of joining the root node of the second partial parse to the last node of the first ... follows: First, the possibility of joining the first two partiM parses is examined, then, either the unification of the first two parses or the second parse is e...
Ngày tải lên: 08/03/2014, 07:20
Báo cáo khoa học: Mutations in the C-terminal domain of ALSV (Avian Leukemia and Sarcoma Viruses) integrase alter the concerted DNA integration process in vitro pot
... highlight the role of the C-terminal domain in the general folding of the enzyme and, hence, on its activity. This study points to the important role of residues at the IN C-terminal domain in the ... 3¢ end of the viral DNA. In the second step (strand transfer), the hydroxyl groups at the 3¢ ends of the processed viral DNA attack a pair of phosphodiester b...
Ngày tải lên: 23/03/2014, 15:21
Báo cáo khoa học: " Medication errors: a prospective cohort study of hand-written and computerised physician order entry in the intensive care unit"
... (where the patient received the drug). The intercepted errors were scored separately on the basis of their possible impact on the patient, if the prescription had been administered as prescribed. The ... blinded to the prescribing system; this could have introduced the potential for bias in the results and is a limitation of the study. Medical errors are among the...
Ngày tải lên: 25/10/2012, 10:39
Tài liệu Báo cáo khoa học: X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate docx
... [8,9]. One of the interesting features of the plant PSs is the presence of a conserved 24 residue insertion in the sequence [9]. This sequence of amino acids, which is missing in the sequence of bacterial ... pantothe- nate from low amounts of pantoate [9]. Here, we report the results of the structural studies of the panto- ate-bound form of the N-terminal...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf
... bc 1 sub-complex, but the presence of only one of these two subunits does not substitute for the other. After the addition of ISP, the binding of the last subunit (i.e. Qcr10p) finally occurs. These find- ings ... also unknown. Furthermore, as in the case of the biogene- sis of other multi-subunit complexes of the mitochon- drial respiratory chain, the assistance...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Looking for the ancestry of the heavy-chain subunits of heteromeric amino acid transporters rBAT and 4F2hc within the GH13 a-amylase family ppt
... the lack of domain B protruding out of the TIM barrel in the place of loop 3 connecting the b3-strand to the a3-helix [9,21]. Sharing domain B by rBATs and GH13 enzymes, and especially the sequence of ... [3,11–13]. Of the three GH families of the clan GH-H, it was the family GH13 that was originally established as the a-amylase family [14–17]. At present it be...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Acetylcholinesterase from the invertebrate Ciona intestinalis is capable of assembling into asymmetric forms when co-expressed with vertebrate collagenic tail peptide doc
... iden- tify the nature of the enzyme and provide additional information about the evolution of the ChEs, including the origins of the acyl pocket, the T exon, and the asymmetric forms of ChE in the vertebrates. Results The ... attached to the triple-stranded helix of ColQ. This result is the first demonstration of the assembly of catalytic subunits of a...
Ngày tải lên: 18/02/2014, 17:20