Báo cáo khoa học: Transport of taurocholate by mutants of negatively charged amino acids, cysteines, and threonines of the rat liver sodium-dependent taurocholate cotransporting polypeptide Ntcp docx

... mutagenesis of Ntcp (Eur. J. Biochem. 270) 1127 Transport of taurocholate by mutants of negatively charged amino acids, cysteines, and threonines of the rat liver sodium-dependent taurocholate cotransporting ... involved in taurocholate transport of the human isoform [21]. We therefore looked for the role of each of the eight cystein...

Ngày tải lên: 17/03/2014, 09:20

... Instead of dividing datasets during 10-fold cross-validation into training and test subsets with the ratio of 9:1 we randomly split the data into training, validation and test sets with the ratio of ... data by expectation maximization 2 which makes them either supervised or unsupervised algorithms. The purpose of this paper is an analysis of the underlying probabili...

Ngày tải lên: 20/02/2014, 04:20

... chromatography and the Gly-extended CCK measured by RIA using Ab 7270. The maturation o f CCK-22-Gly was abolished in t he CCK(K61A) mutant which is s een by the disappearance of thepeakoftheCCK-22peakelutingatK d 0.8 ... activity of S. cerevisiae An in vitro assay was established using crude preparation s from of BJ2168 (Table 1) and synthetic CCK-33 as substrate (Fig. 1A...

Ngày tải lên: 07/03/2014, 16:20

... by defective transport of the cationic amino acids lysine, arginine and ornithine at the basolateral membrane of the polar epithelial cells in the intestine and renal tubules. LPI is caused by mutations ... confirming the presence of the system y + L in human platelets (Fig. 2). Data indicate that platelet L -arginine transport mainly occurs by the action o...

Ngày tải lên: 08/03/2014, 02:20

... potential tag B divided by the frequency of A. Subsequently, it was changed to the frequency of A followed by B divided by the product of the frequency of A and the frequency of B (Marshall, 1983: ... for the initial upper case form (when not acting as the standard beginning -of- sentence marker) and the other for the initial lower case form. The...

Ngày tải lên: 08/03/2014, 18:20

... this: A D(2) B E (1) There are nonterminals on the left-hand side (LHS) and in parentheses on the right-hand side (RHS). Each row of the production describes rewriting in a different component text of a multitext. ... texts, with lengths . The notation in- dicates that the Goal item must span the input from the left of the first word to the right of the last word...

Ngày tải lên: 20/02/2014, 16:20

... line) is the result of using the word pair to distinguish among senses of the same verb. The other (dotted line} is the result of using the verb form itself. The X-axis is the number of classified ... of a set B nij : the number of nouns which are included in both the ith cluster of A and the jth cluster of B n.j : the number ofnouns which are...

Ngày tải lên: 20/02/2014, 21:20

Ngày tải lên: 22/02/2014, 03:20

... [2,3], a rate-limiting enzyme in the synthesis of NAD + from nicotin- amide. Visfatin ⁄ PBEF ⁄ NAMPT is synthesized and secreted in adipose tissue by adipocytes, and mostly by macrophages, and circulates ... the absence or in the presence of the PPARc agonist GW1929 added at the start of the differentiation process [25]. As shown in Fig. 4B, the expression of v...

Ngày tải lên: 06/03/2014, 22:21

... hydroxylations of testosterone are on the b face. This information is of interest in considerations of the steroselectivity of P450 3A4 and general considerations about the juxtaposition of the substrate ... array detector. MS (time -of- flight) An aliquot (5%, v/v) of the eluent from the HPLC column was s plit to the mass spectrometer u sing a splitte r from LCPack...

Ngày tải lên: 07/03/2014, 16:20