Báo cáo khoa học: Bioenergetics of the formyl-methanofuran dehydrogenase and heterodisulﬁde reductase reactions in Methanothermobacter thermautotrophicus pot

... 270)75 Bioenergetics of the formyl-methanofuran dehydrogenase and heterodisulﬁde reductase reactions in Methanothermobacter thermautotrophicus Linda M. I. de Poorter1, Wim G. Geerts1, Alexander ... metabolism of meth-anogenic archaea. The bioenergetics of the reactions in vivowere studied in chemostat cultures and in cell suspensions of Methanothermobacter thermautotrophicus metabolizing atdeﬁned ... Quiteremarkably, formyl-methanofuran was the predominantFig. 5. Bioenergetics of formyl-methanofuran synthesis in cell suspen-sions of M. thermautotrophicus. Cell suspensions of M. thermautotro-phicus...

Báo cáo khoa học: Structure of the O polysaccharides and serological classiﬁcation of Pseudomonas syringae pv. porri from genomospecies 4 doc

... diﬀer in the position of substitution of one of the Rha residues and in the site of attachment of GlcNAc, were found in the two strains stud-ied, O repeat 1 being major in strain NCPPB 3365 and ... similar structures differing fromeach other in the position of substitution of one of the rhamnose residues (RhaIV)inthemainchainandthesite of attachment of the GlcNAc side chain (at RhaIIorRhaI). ... LPS of most otherP. syringae strains studied [23,31]. This suggests a difference in either the LPS core structure or /and in the mode of the attachment of the OPS to the core. Therefore, strains...

Báo cáo khoa học: Role of the hinge peptide and the intersubunit interface in the swapping of N-termini in dimeric bovine seminal RNase pptx

... result alsoprovides indirect evidence of correct pairing of the inter-chain disulﬁde bridges in the recombinant sample [11]. The kinetics of the N-terminal arms swapping in the P19A-BS-RNase ... Role of the hinge peptide and the intersubunit interface in the swapping of N-termini in dimeric bovine seminal RNaseCarmine Ercole1, Francesca Avitabile1, Pompea Del Vecchio1, Orlando ... into an apparent molar heat capacity takinginto account the instrument calibration curve and the buffer–buffer scanning curve, and by dividing each datapoint by the scan rate and the protein...

Báo cáo khoa học: Structures of the O-polysaccharides and classiﬁcation of Proteus genomospecies 4, 5 and 6 into respective Proteus serogroups ppt

... lipopolysaccharides, inclu-ding those of 27 strains of P. vulgaris, 39 strains of P. mirabilis, 24 strains of P. penneri, one strain of P. myxofaciens, one strain of P. hauseri and Providen-cia ... includingO-polysaccharides of Proteus [16].Studies of the O-polysaccharides of Proteus genomo-species 5 and 6 and the comparison of the correspond-ing13C NMR spectra indicated that they are identicalto those of ... 3C), the cross-reac-tions being almost identical to the reactions of the homologous LPS (1 : 51 200). Inhibition of the reac-Fig. 3. EIA binding curves of Proteus genomospecies 4 (A), 5 (B)and...

Báo cáo khoa học: Investigation of the substrate speciﬁcity of a b-glycosidase from Spodoptera frugiperda using site-directed mutagenesis and bioenergetics analysis pdf

... Bioscience). The nonretained proteins were washed out in the d ialysisbuffer, while the retained proteins were eluted f rom the column using an NaCl gradient prepared in the same buffer. The presen ce of ... 1 aninteresting model for using to study the molecular basis of the enzymatic speciﬁcity.Having a better understanding of the m olecular basis of b-glycosidase speciﬁcity would result in an ... monosaccharides from the nonred uc-ing e nd of di- and/ or oligosaccharides. The nonreducingmonosaccharide residue binds at the glycone subsite (subsite)1), w hereas the r emaining part of the substrate...

Báo cáo khoa học: "Impact of computerized physician order entry on medication prescription errors in the intensive care unit: a controlled cross-sectional trial"

... 0.001).Conclusion The ICU computerization, including the medicationorder entry, resulted in a significant decrease in the occurrence and severity of medication errors in the ICU.Introduction In 1999, the Institute ... where rapid intervention of the clinical pharma-cist intercepted the administration of this overdose. The non-intercepted potential ADEs were mainly dosing errors orincompleteness of low molecular ... the clinical pharmacist, comprising 1,286 in the C-U and 1,224 in the PB-U. In the C-U, 44 MPEs occurred versus331 in the PB-U (3.4% versus 27.0%, P < 0.001). Overall, the ICIS resulted in...

Báo cáo khoa học: " Effect of the medical emergency team on long-term mortality following major surgery"

... about the force with which the victims were hit and swept away by the wave.Antiinfective therapyOur intial choice of anti-infective therapy was a combination of a potent quinolone combined with ... Cefepim Imipenem Meropenem Gentamicin Tobramycin Amikacin Ofloxacin Ciprofloxacin Clindamycin Fosfomycin Erythromycin Rifampicin Vancomycin Teicoplanin Isolates ... had combined injuriesto the thorax (for instance, pneumo-/hemopneumothorax),including intrapulmonary contusions and lesioning, and frac-tures of the extremities, both open and closed. Initial...

Tài liệu Báo cáo khoa học: Motion of the Ca2+ -pump captured ppt

... (long-distance move-ment of the N-domain and rotational motion of the A-domain) of SERCA during the ATP-mediated iontransport reaction [14,16–19]. The single line scanning method [8,15], in which anAFM ... accu-mulates Ca2+inside the SR against its concentrationgradient. The importance of the SR Ca2+-pump wasrealized in the early 1960s by Ebashi and Lipmann[5,6] and, since then, most of the molecular ... to the heightdifference between the E1Ca2+form [14], in which the N-domain is widely separated from the A-domain and P-domain, and the other compacted forms of SERCA (E1ATP, E1P, E2P, and...

Tài liệu Báo cáo khoa học: Role of the cag-pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis pptx

... control the amount of intracellu-lar CagAPY. Cortactin, ezrin and vinculin are all Srcsubstrates, and Src inactivation causes dephosphoryla-tion of these proteins and is crucial for triggering ... distribution,making them unsuitable for the investigation of b-cate-nin signalling [29]. In support of this aspect, usingMadin–Darby canine kidney cells that expressE-cadherin and b-catenin without ... (11). In this manner, the bacteria could access integrins and inject CagA (12). Injected CagA can then induce the massive disruption of cell junctions(13) and a loss of cell polarity (14). The induction...

Tài liệu Báo cáo khoa học: Upregulation of the a-secretase ADAM10 – risk or reason for hope? docx

... delivery of furin into the brain of AD model mice increaseda-secretase activity and reduced b-amyloid protein(Ab) production in infected brain regions [21], demon-strating the in vivo relevance of ... protein interaction partners of ADAM10. The tissue inhibitors of metalloproteinases 1 and 3 havebeen shown to inhibit ADAM10 in vitro [102] and the reversion-inducing cysteine-rich protein with ... overexpres-sion of ADAM10 to various extent were inconspicuous in morphology, breeding and in daily handling [10].This indicates that, by overexpression of ADAM10 in the brain, the homeostasis of the entire...

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