Báo cáo khoa học: "Construct State Modification in the Arabic Treebank" doc

... resistant strains [3]. Pathogenic Yersiniae are typically taken up through ingestion and first reach the intestine. The Yersinia surface protein invasin binds to b1 integrins on the apical surface ... invasion in order to prevent uptake and killing. In addition to actin, other host cell proteins have been shown to bind to the virulence factor YpkA, including OTUB1 [13]. In order...

Ngày tải lên: 16/02/2014, 15:20

... described for the sulfuration of the C-terminal glycine in ThiS and MoaD, involved in thiamine biosynthesis and molyb- dopterin biosynthesis, respectively, and for the sulfura- tion of uridine in tRNA ... the carboxamide group of glycine in the peptide chain remains to be shown. Neither the functions of the five modifications nor whether the modifications are present in...

Ngày tải lên: 16/03/2014, 05:20

... and MMP-1 bind the a2b1 integrin via the I domain of the a2 integrin subunit and that the linker peptide and the hemopexin domain of MMP-1 are required for optimal binding [39]. Basal keratinocytes ... in their function. The N-terminal pro- peptide acts to maintain the latency of the MMPs by the presence of a cysteine residue in the active site coordinated to the cat...

Ngày tải lên: 15/03/2014, 00:20

... the over- all number of these modifications is low, the density of modifications is much the same as in the rest of the lin- ker histones. It is the shortness of the N-terminal tails Table 1. Alignment ... core histones. There is also a great diversifica- tion in the H1 variants within a single species such as H. sapiens, predominantly in the N-terminal and C-ter- minal t...

Ngày tải lên: 18/02/2014, 08:20

... or signalling pathway in vivo is coordinated with that of the other proteins in the same pathway, and the func- tioning of the pathway itself is coordinated with that of the other pathways within the ... by binding of intracellular proteins, such as protein tyrosine kinases, to the cytoplasmic portion of the receptors in the case of signalling through lymphocyte recept...

Ngày tải lên: 19/02/2014, 06:20

... protein that contains one domain and no disulfide bonds. Its stability in the native state may be maintained mainly by key amino acids. In this study, two point-mutated proteins each with a single ... polypeptide chains into the compact form of the native state. In this study, the effects of mutating W140 [10] on SNase protein conformation and stability were Keywords aromatic...

Ngày tải lên: 20/02/2014, 01:20

... near the flexible C terminus of SNase. Changes in the fluorescence intensity of W140 reflect a change in the surrounding hydrophobic environment of the tryptophan and thus indicate a change in the overall ... with the thermodynamic results obtained from thermal unfolding (DH cal ) (for data see the following section and Table 1). These data indicate that the mutants are muc...

Ngày tải lên: 07/03/2014, 21:20

... divided in two phases according to the intensity and the duration of the stress. An initial adaptive response culminates in the temporary inhibition of protein synthesis, providing cells with the ... synthesis was initially hindered following stearate administration and was completely interrupted at longer incubation periods. Interestingly, the interruption of TAG synthe- sis...

Ngày tải lên: 14/02/2014, 22:20

... occur- ring in many different combinations are the P-loop nucleotide triphosphate hydrolase domain, the epider- mal growth factor (EGF) domain, the SH3 domain, the P-kinase domain and the domains involved ... of the deletion at each domain position within the group of proteins containing a given number of domains. We found that the domain deletions are more com- mon at eithe...

Ngày tải lên: 19/02/2014, 07:20

... substrate carbinolamine intermediate; III, iminoquinone intermediate; IV, product Schiff base intermediate; V, aminoquinol intermediate. In the oxidative half-reaction the ami- noquinol intermediate ... substrates. The lack of inhibition observed with benzylamine (Fig. 5A) in comparison to the inhibition observed with tryptamine (Fig. 5B) suggests differences in binding of the...

Ngày tải lên: 19/02/2014, 07:20