Báo cáo khoa học: Secretion of the mammalian Sec14p-like phosphoinositide-binding p45 protein pptx
Báo cáo khoa học: Secretion of the mammalian Sec14p-like phosphoinositide-binding p45 protein pptx
... vesicles and therefore cannot colocalize with
p45.
Fig. 3. Secretion of the SEC14 domain of p45. (A) The hydrophilicity plot of p45 protein and location of the SEC14 and GOLD domains. Note
that the strongly ... Merkulova et al. Secretion of p45 Sec14p-like protein
FEBS Journal 272 (2005) 5595–5605 ª 2005 FEBS 5605
Secretion of the mammalian Sec14p-l...
Tài liệu Báo cáo khoa học: Role of the cag-pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis pptx
... colonizes the surface area of the
gastric mucosa in the human stomach and is one of
the most adapted microbial pathogens. 50% of the
world’s population carries this bacterium, causing
chronic, often ... formation of VirB2-VirB5 complexes followed by T-pilus assembly. The assem-
bled T4SS then triggers the secretion of substrates from the bacterial cytoplasm direc...
Tài liệu Báo cáo khoa học: Regulation of the members of the mammalian heat shock factor family doc
... post-translational
modifications
HSF1 is the prototype of all HSFs and the mammalian
counterpart of the single HSF of yeasts, nematodes
and fruit flies [3,27–29]. Deletion experiments of the
Drosophila Hsf demonstrated ... induce
the synthesis of HSPs that act as molecular chaperones
through binding to the hydrophobic surfaces of
unfolded proteins, thereby facilitating...
Tài liệu Báo cáo khoa học: Impact of the native-state stability of human lysozyme variants on protein secretion by Pichia pastoris doc
... between the levels of expres-
sion in the different experiments (Table 2). The results
show a clear relationship between the thermal stability
of each variant and the level of protein secreted to the
supernatant ... both
variants suggesting that the overall structure of the
folded proteins is unlikely to differ significantly from
that of the WT protein. The for...
Báo cáo khoa học: Architecture of the Helicobacter pylori Cag-type IV secretion system pdf
... proteins. Other components are
essential for the formation of the T4SS complex: VirB1
allows for the insertion of the system in the periplasm
and VirB3, the function of which is unknown, is often
associated ... helices from each of the
monomers pointing into the centre of the ring to form
the claws of the grapple [28]. VirB11 proteins are
dynamic assemblies,...
Báo cáo khoa học: Binding of the volatile general anesthetics halothane and isoflurane to a mammalian b-barrel protein doc
... binding of
anesthetic to the four-a-helix bundle scaffolds is associ-
ated with a stabilization of the folded conformation of
the protein. Halothane has been shown to increase the
stability of the ... (http://www.microcal.com/).
This software provides the best-fit values for the heat of
binding (DH°), the stoichiometry of binding (n), and the
association constant...
Báo cáo khoa học: " Effect of the medical emergency team on long-term mortality following major surgery"
... suffered at least loss of one rel-
ative, for example, a partner or child, and two mothers of our
cohort lost both of their children. The majority of patients com-
plained of nightmares, emotional ... aftermath
With respect to the tsunami's psychoemotional aftermath, the
full impact of the wave on the mental health of the survivors is
still unknown [2]. In Febru...
Tài liệu Báo cáo khoa học: Motion of the Ca2+ -pump captured ppt
... as the ATP-unbound and Ca
2+
-bound
E1Ca
2+
form. In the histogram (Fig. 2A) of the dis-
tribution of the height of the projection of the embed-
ded molecule above the flat membrane surface, the
average ... Histograms of the height differences between the top of
SERCA and the surface of the membrane. Statistical section analy-
ses of SERCA were performed...
Tài liệu Báo cáo khoa học: Upregulation of the a-secretase ADAM10 – risk or reason for hope? docx
... for a therapeutic approach in AD [13–15].
Protein structure and gene
organization of ADAM10
The enzyme ADAM10 belongs to the subgroup of
metzincins within the zinc proteinases family. The typi-
cal ... that the
prodomain of ADAM10 acts not only as a transient
inhibitor, but also as an internal chaperone in the mat-
uration of the enzyme. Accordingly, the viral delive...
Tài liệu Báo cáo khoa học: Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis pdf
... preferentially
the phosphorylation of the p46 isoform of JNK,
whereas sorbitol treatment induced phosphorylation of
both the p46 and p55 isoforms. To confirm functional
activation of the JNK signaling ... phosphorylation of the transcription factor
c-JUN was attenuated. Upon expression of wild-type JSP1, a subpopula-
tion of cells, with the highest levels of the p...