Báo cáo khoa học: The human cytomegalovirus-encoded chemokine receptor US28 induces caspase-dependent apoptosis pptx

... FEBS 4177 O. Pleskoff et al. HCMV chemokine receptor US28 induces apoptosis The human cytomegalovirus-encoded chemokine receptor US28 induces caspase-dependent apoptosis Olivier Pleskoff 1,2 , ... expressing either the HCMV chemokine receptors US28, various cellular chemokine receptors, the proapoptotic Bax protein as a positive control for apoptosis ind...

Ngày tải lên: 16/03/2014, 22:20

... epileptic convulsions was due to the ingestion of Ginkgo remedies. However, they neither specify the respective remedies, nor do they mention their composition. Therefore, the possi- bilities of overdosage ... relevant concentrations of the toxin were tested in vitro [8]. It follows that the interaction between ginkgotoxin and PKH is a rather specific process which affects the key...

Ngày tải lên: 07/03/2014, 10:20

... unique among the sciences in the crisis it faces. The next generation will forgive us for the most egregious shortcomings in theory construction and technol- ogy development, but they will not ... languages. The kind of processing we wish to enable is much like the large-scale systematic research that motivated the Human Genome Project. One of the greatest impacts of having...

Ngày tải lên: 16/03/2014, 23:20

... apply the technique to the study of affixes in the three-vowel-string words, that is, CVCVCVC words. There are some novelties which arise. Among these, the most important is certainly the occurrence ... to other suffixes. Evidently these could not be found from an investiga- tion of the two-vowel-string words, and so they did not make their appearance in Part I. Another new...

Ngày tải lên: 07/03/2014, 18:20

... leads to the disassembly of the spherical capsid inside the virion. Some of the folded domains of Gag are then able to reassemble as inde- pendent proteins. The matrix protein (MA; the Gag N-terminal ... involved either in the assembly of the immature HIV-1 capsid, or in the reassembly of CA into a mature capsid. The detailed description of the structure and conformation...

Ngày tải lên: 18/02/2014, 06:20

... that the higher the helicity, the higher the inhibition of assembly. The affinity of NAYD-1 for CTD is the largest reported to date, with values close to 1 lm. The difference in affinity from the ... (C) The structure of NTD in complex with the small organic molecule CAP-1 (accession no. 2pxr) [36]; the helices are in red, the b-sheets in yellow and the loops in green....

Ngày tải lên: 18/02/2014, 06:20

... present for the last four residues at the C-terminus. The stereochemistry of the model has been assessed using the program procheck [23]. Ninety per cent of the residues fall in the most favoured regions ... with the hydrogen bonds established by DHAP with the metal-coordinating solvent molecule w1. The por- tion of the 2F o )F c electron density map covering the DHAP...

Ngày tải lên: 18/02/2014, 06:20

... of these molecular chaperones with substrates will foster disease. Therefore, this review considers the role of sHSPs in several human medical conditions and it ends with a discussion of their therapeutic ... Among the three cancers, sarcoma cells possess the most Hsp25, the rodent equivalent of human Hsp27, and the protein builds up upon drug treatment, suggestive of a role in...

Ngày tải lên: 19/02/2014, 18:20

... be estimated trivially as the proportion of training samples be- longing to the class. Thus the critical aspect of clas- sification by Bayes’ Theorem is to estimate the con- ditional distribution ... The necessary documents and their corresponding labels are built from the spans of text that surround the anchor words excellent and poor. More formally, a labeled corpus may be prod...

Ngày tải lên: 20/02/2014, 16:20

... as compared to the other attachment, which is to a VP. 123 The burglar blew open the safe with the dynamite (Minimal attachment to VP) The burglar blew open the safe with the diamonds (Non-minimal ... NP) In the case of the non-minimally attached version, the correct attachment (to the NP) would be attempted only after the minimal attachment to the VP had fi...

Ngày tải lên: 22/02/2014, 09:20