Báo cáo khoa học: Oxidative stress is involved in the permeabilization of the inner membrane of brain mitochondria exposed to hypoxia/reoxygenation and low micromolar Ca2+ Lorenz Schild1 and Georg Reiser2 doc

... Oxidative stress is involved in the permeabilization of the inner membrane of brain mitochondria exposed to hypoxia/reoxygenation and low micromolar Ca 2+ Lorenz Schild 1 and Georg Reiser 2 1 ... that mitochondria contribute to the induction of oxidative stress during ischemia ⁄ reperfusion in brain. There is a growing body of...

Ngày tải lên: 16/03/2014, 22:20

... relative to the level of wild-type tobacco, taken as 1, referring to the transcripts of CAT1 in the same samples. (C) The total activities of the antioxidant enzymes SOD, CAT and APX in the tobacco ... species scavenging capability and oxidative stress tolerance. These results increased our understanding of the role of the group C GhMPK2 gene in mul...

Ngày tải lên: 14/03/2014, 23:20

... nitrate and H 2 O 2 , are normally produced in the brain. H 2 O 2 is converted into water by catalase and glutathione peroxidase, which involves GSH, a cofactor of this enzyme [5,8]. GSH is one of the ... related to the mechanisms involved in the initiation and ⁄ or propagation of seizures induced by pilocarpine. Our results are in agreement with another stu...

Ngày tải lên: 19/02/2014, 16:20

... of biosynthesis and sites of utilization. Little is known about the effect of oxidative stress on the distribution of low- molecular-mass thiols and their exchange rate between tissues. In this ... key role in defense against oxidative stress. The availability of GSH is ensured in tissues by systems devoted to its mainte- nance in the reduced state...

Ngày tải lên: 16/03/2014, 02:20

... [7,52,57]. Nevertheless, independently of the resulting effect of the thermal stress, all mechanisms point to the involve- ment of oxidative stress in the early stages of symbiosis breakdown. In fact, ... be involved in necrosis or in so-called postmitochondrial phase of apoptosis [26]; or (b) they could be involved in the initiation phase of apoptos...

Ngày tải lên: 30/03/2014, 10:20

... the Michigan doctors and Pennsylvania dentists, produced a list of all the people who were either doctors or dentists and who lived in either Michigan or Pennsylvania. This is the state of ... databasesl" has resulted in this panel, which is supposed to debate the necessity of continuing work in this area rather than to debate technical issues in...

Ngày tải lên: 21/02/2014, 20:20

... differences in function or localization of these isoforms in the brain. In order to try to understand how these isoforms may differ, we exam- ined the expression of the isoforms known to be tran- scribed ... reported in fetal liver and brain [2], but no isoforms containing exon 3 have yet been described. The RCAN1 protein is able to bind to and inhibit...

Ngày tải lên: 16/03/2014, 11:20

... entirely in the Brij-96- insoluble domains, and only partially in the Triton X-100-insoluble membrane microdomains. We studied the sensitivity of these domains to cholesterol removal, as well as their ... on the fact that Triton X-100 rafts are most often isolated using a 1% concentration, and the upper limit of the solubility of Brij-96 at 4 °C is 0.5%. Each l...

Ngày tải lên: 16/03/2014, 23:20

... which, in turn, regulate the expression of genes involved in osmotic stress acclima- tion. In addition to intracellular signaling mechanisms, the systemic response to osmotic stress in euryhaline ... [21] and in the closing or opening of apical crypts of gill chloride cells [22]. Furthermore, changes in ion transport during hyper- and hypotonic stress r...

Ngày tải lên: 18/02/2014, 16:20

... for 30 min with preformed macromolecular complex consisting of avidin and biotinylated peroxidase (Vector Laboratories, Burlingame, CA), which retains biotin-binding sites. The staining reaction ... culturing them up to passage 26 or 28. Intracellularly, senescence was exerted and maintained through the function of the cyclin-kinase inhibitors p21 CIP1 and p16 INK4A [32]. I...

Ngày tải lên: 19/02/2014, 00:20