... correlation between 8OHdG and MDA levels (r = 0.463, P < 0.010) and negative correlations between 8OHdG and vitamin A (r = –0 .419, P < 0.021) and b-carotene levels (r = –0 .341, P = 0.065). However, ... nucleus (N), 92 N+C– cases with survivin expression on only the nucleus, 12 N–C+ cases with survivin expression on only one side of the cytoplasm, and 21 N–C– cases that...
Ngày tải lên: 19/02/2014, 07:20
... Binding positions P1 P6 and the N- and C-termini are labelled. (C) Schematic representation of hydrogen bonds (broken lines, < 3.5 A ˚ ) between importin-a and the CLIC4 NLS peptide, P1 AKKYRN P6 . ... main-chain and side-chain atoms of the mod- elled CLIC4 peptide show a good fit to the electron density (Fig. 1B). The peptide residues 20 2–2 07 corre- spond to the key bin...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: Multifunctional host defense peptides: Antimicrobial peptides, the small yet big players in innate and adaptive immunity docx
... different scenarios, and modulating the local immune response. Phagocytic cells, neutrophils and monocytes that are recruited through a-defensins, HNP 1–3 and b-defen- sins hBD3 and hBD4, and mast cells ... small cationic antimicrobial peptides – particularly human cathelicidins and defen- sins – to the immune response and disease, highlighting recent advances in our u...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: Destabilization of psychrotrophic RNase HI in a localized fashion as revealed by mutational and X-ray crystallographic analyses pdf
... residues 29, T34 and E131 are shown. The hydrogen bonds between N29 and Oc and T34 and Oc, and between N29 and Nd and E131 and Oe2, in the wild-type protein are shown as green broken lines, and the ion ... of Y24, residue 39, F41 and Q149 are shown. The hydrogen bonds between D39 and Od1 and Q149 and Ne, and between D39 and Od2 and Q149 and Ne, in the wild-ty...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: An ecdysteroid-inducible insulin-like growth factor-like peptide regulates adult development of the silkmoth Bombyx mori docx
... organizations and physiological func- tions: insulin is a heterodimeric peptide consisting of an A-chain and a B-chain, whereas IGFs are single- chain peptides with domains B, C, A and D, and the major ... identical peptide sequence composed of a putative 20 amino acid signal peptide and a 68 amino acid peptide belonging to the insulin family (Fig. 3C). If the signal peptid...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Analysis of the molecular dynamics of medaka nuage proteins by fluorescence correlation spectroscopy and fluorescence recovery after photobleaching doc
... GFP (EGFP)–Olvas, mRFP–Olvas, EGFP–Nanos, mRFP–Nanos, EGFP– Tudor, and mRFP–Tudor chimera], and was transcribed from the CMV promoter. In vitro RNA synthesis and microinjection The olvas–GFP described ... cytoplasm. Olvas–GFP and Nanos–RFP, and Olvas– RFP and Tudor–GFP, are colocalized in the granules. Dynamic nature of medaka nuage proteins I. Nagao et al. 344 FEBS Journal 275...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5¢-phosphate synthases of fungi and archaea docx
... fungi and archaea W. Ro ¨ misch-Margl et al. 4412 FEBS Journal 275 (2008) 440 3–4 414 ª 2008 The Authors Journal compilation ª 2008 FEBS Riley M, Schaecter M & Umbarger HE, eds), pp. 65 7– 664. ... nucleotide reduction in fungi and archaea FEBS Journal 275 (2008) 440 3–4 414 ª 2008 The Authors Journal compilation ª 2008 FEBS 4413 Fig. S2. Boundary sedimentation and se...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khoa học: DNA modification with cisplatin affects sequence-specific DNA binding of p53 and p73 proteins in a target site-dependent manner pptx
... P53 and prognosis: new insights and further complexity. Cell 120, 7–1 0. 2 El-Deiry WS (2003) The role of p53 in chemosensitivity and radiosensitivity. Oncogene 22, 748 6–7 495. 3 Appella E & Anderson ... used antibody to HA and obtained analogous band patterns to those obtained with p53 (Fig. 2; lanes 6–7 , bands SR 73b and SR 73d ), confirming the specificity of the observ...
Ngày tải lên: 19/02/2014, 05:20
Tài liệu Báo cáo khoa học: Induction of uPA gene expression by the blockage of E-cadherin via Src- and Shc-dependent Erk signaling docx
... and b) and MCF7 cells (c and d) were grown for 2 days to 6 0–7 0% confluence and then treated with control or Decma supernatant for 6 h before recording. (C) MCF7 cells were treated with Decma and ... protein A and G-Sepharose were from GE Healthcare Europe GmbH (Otelfingen, Switzerland). Cells and transfection MCF7 and T47D cells were cultured in DMEM ⁄ HAMs F12 [Invitrogen A...
Ngày tải lên: 19/02/2014, 05:20
Tài liệu Báo cáo khoa học: Characterization of the interaction between the plasma membrane H+-ATPase of Arabidopsis thaliana and a novel interactor (PPI1) doc
... and PPI1 FEBS Journal 272 (2005) 586 4–5 871 ª 2005 FEBS 5865 membrane incubated with GST–AHA1(84 6–9 49) (Fig. 1B); the signals were specific as no signal was detected when free GST was spotted and ... that PPI1 588 His 6 and GST–AHA1(84 6–9 49) bound each other in overlay experiments both when a membrane spotted with GST–AHA1(84 6–9 49) was incubated with PPI1 588 His 6 (Fi...
Ngày tải lên: 19/02/2014, 07:20