Báo cáo khoa học: Relationship between the structure of guanidines and N-hydroxyguanidines, their binding to inducible nitric oxide synthase (iNOS) and their iNOS-catalysed oxidation to NO pptx
Báo cáo khoa học: Relationship between the structure of guanidines and N-hydroxyguanidines, their binding to inducible nitric oxide synthase (iNOS) and their iNOS-catalysed oxidation to NO pptx
... specificity of iNOS Relationship between the structure of guanidines and N-hydroxyguanidines, their binding to inducible nitric oxide synthase (iNOS) and their iNOS-catalysed oxidation to NO David ... constants related to the binding of l-Arg [10–14] and NOHA [10], nothing is known about the thermodynamics and kinetics of the b...
Ngày tải lên: 16/03/2014, 22:20
Tài liệu Báo cáo khoa học: Insights into the structure of plant a-type phospholipase D Susanne Stumpe, Stephan Konig and Renate Ulbrich-Hofmann ¨ ppt
... A2 to E153 should occupy 16% of the molecular volume, and therefore seems too large to represent the lid-like structure at the top of the left view in Fig. 3. We speculate that the loosely structured ... on the opposite side belongs to the C2 domain (141 amino acids) with its extended loops, whereas the lid-like region at the top represents another flexible part...
Ngày tải lên: 19/02/2014, 02:20
Báo cáo khoa học: Discriminating between the activities of human cathepsin G and chymase using fluorogenic substrates potx
... the potential for their substrate -binding subsites to discriminate between their substrate specificities, aiming to better understand their respective role dur- ing the progression of inflammatory ... of the higher electronegative charge of the O atom of the Ser side-chain compared to that of the sulfur atom in the Cys side-chain; P3¢ Leu for Pro because...
Ngày tải lên: 28/03/2014, 22:20
Báo cáo khoa học: Piecing together the structure of retroviral integrase, an important target in AIDS therapy pptx
... as no average structure is available). The rmsd between these two structures is 1.2 A ˚ . The devia- tions between the NMR structures of the isolated CTD and the crystallographic models of the ... Owing to the symmetry of the complex, the second IBD interacts with the corre- sponding areas of molecules B and A of the CCD. The interactions of...
Ngày tải lên: 29/03/2014, 23:20
Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt
... acids and amino acid deriva- tives have little or no effect on the solvation properties of the substrate and the enzyme active sites or on their thermodynamic activities. Another explanation for these ... taurine and dimethyl- glycine have not been published elsewhere. We have therefore measured the thermodynamic parameters of RNase-A in the presence of these amino a...
Ngày tải lên: 07/03/2014, 00:20
Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf
... addition of ISP and Qcr10p). On the other hand, in the transition from the 500 kDa band to the 670 kDa band, a structural rearrangement of the bc 1 complex may occur due to the binding of ISP and ... bind to each other during the assembly of the bc 1 complex is also unknown. Furthermore, as in the case of the biogene- sis of other multi-subunit comp...
Ngày tải lên: 18/02/2014, 08:20
Báo cáo khoa học: Distinguishing between different pathways of bilayer disruption by the related antimicrobial peptides cecropin B, B1 and B3 pptx
... this. Figure 2B,D shows the non- specific binding of CB and CB1 (respectively) to the chip surface in the absence of liposomes; the level of nonspecific binding between peptides and sensor chip surface ... surfactant Polysorbate 20. The purpose of the surfactant is to reduce sample loss caused by the adsorption of hydrophobic molecules to the surfaces...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: Correlation between conformational stability of the ternary enzyme–substrate complex and domain closure of 3-phosphoglycerate kinase potx
... requirement of either only one or both substrates in causing domain movement and the ques- tion of whether binding of a single substrate to one of the two domains can also stabilize the structure of the other ... T, and I N and I U are the intercepts and m N and m U are the slopes of the pre- and post-transitional base lines of the raw data, res...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: Relationships between the ethanol utilization (alc ) pathway and unrelated catabolic pathways in Aspergillus nidulans pptx
... induction of alcA while alcR and aldA expression do not exceed their basal, noninduced levels (results not shown). These data thus show that there is no correlation between the inducing capabilities of ... with our previous data and show that aliphatic and cyclic ketones directly induce the alc genes. There is no correlation between the inductive capacities of keto...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo khoa học: A unique tetrameric structure of deer plasma haptoglobin – an evolutionary advantage in the Hp 2-2 phenotype with homogeneous structure pot
... positions and number of Cys residues (total of seven) are com- pletely identical between the two species (the one at the C-terminal region is not shown). Divergence of the amino acids within the species ... did not identify any carbohydrates associated with the a-chain of either species (data not shown). Hypothetical model for the formation of the deer Hp tetramer...
Ngày tải lên: 23/03/2014, 07:20