Báo cáo khoa học: Affinity of S100A1 protein for calcium increases dramatically upon glutathionylation docx
Báo cáo khoa học: Affinity of S100A1 protein for calcium increases dramatically upon glutathionylation docx
... Affinity of S100A1 protein for calcium increases
dramatically upon glutathionylation
Graz_ yna Goch, Sergiusz Vdovenko, Hanna Kozłowska and Andrzej Bierzyn
˜
ski
Institute of Biochemistry ... probe of
protein- surface hydrophobicity. S -Glutathionylation of the single cysteine
residue (85) of the a subunits leads to a 10-fold increase in the affinity of
the pr...
Tài liệu Báo cáo khoa học: Affinity and kinetics of proprotein convertase subtilisin ⁄ kexin type 9 binding to low-density lipoprotein receptors on HepG2 cells docx
... gain -of- function mutants of
PCSK9 reduced binding of [
125
I]TC-PCSK9. The Scatchard plot of the
binding-inhibition curve was curvilinear, indicative of high -affinity and
low -affinity sites for ... higher -affinity
and lower -affinity binding sites are listed in Table 1.
The high -affinity and the low -affinity sites accounted
for 25% and 75% of the total binding, respective...
Tài liệu Báo cáo khoa học: Animal models of amyloid-b-related pathologies in Alzheimer’s disease docx
... disease pathogenesis
Familial forms of AD, with an autosomal dominant
mode of inheritance, account for < 2% of all AD
cases. Onset is most often before 65 years of age, and
the penetrance is nearly ... cerebral microvascular accumu-
lation of amyloid beta -protein in transgenic mice
expressing low levels of a vasculotropic Dutch ⁄ Iowa
mutant form of amyloid beta -protein...
Tài liệu Báo cáo khoa học: Inhibitory effects of nontoxic protein volvatoxin A1 on pore-forming cardiotoxic protein volvatoxin A2 by interaction with amphipathic a-helix doc
... silver
staining.
Co-pull-down experiment
For further study of the protein protein interaction, we
performed a co-pull-down experiment to analyze the num-
ber of binding sites of VVA1 and VVA2. VVA1 (VVA2
beads) ... has two
binding sites for interaction with two molecules of
VVA2, and that large amounts of free VVA2 can use
VVA1 as a basis for the formation of VVA2 oligomer...
Tài liệu Báo cáo khoa học: "Web augmentation of language models for continuous speech recognition of SMS text messages" docx
... Proceedings of the 12th Conference of the European Chapter of the ACL, pages 157–165,
Athens, Greece, 30 March – 3 April 2009.
c
2009 Association for Computational Linguistics
Web augmentation of language ... size of the web mixture
LM is limited to the size of the baseline
in-domain LM.
1 Introduction
An automatic speech recognition (ASR) system
consists of acoustic models...
Báo cáo khoa học: Molecular mechanisms of the phospho-dependent prolyl cis ⁄ trans isomerase Pin1 docx
... SRSRpT
212
PpS
214
LPpT
217
PPTR peptide of Tau. The cis conformation for the Pro219 is
below the limit of detection. Upon addition of a catalytic amount of Pin1, enhanced cis ⁄ trans isomerization of the pThr212-Pro213 ... involve-
ment of two major classes of isomerases, the
cyclophilins (Cyps) and the FK506-binding proteins
(FKBPs), in the protein- folding process, where...
Báo cáo khoa học: Versatile regulation of multisite protein phosphorylation by the order of phosphate processing and protein–protein interactions pptx
... December
2006)
doi:10.1111/j.1742-4658.2007.05653.x
Multisite protein phosphorylation is a common regulatory mechanism
in cell signaling, and dramatically increases the possibilities for protein
protein interactions, conformational regulation, ... special cases. The order of phos-
phate processing and the characteristics of protein protein interactions
turn out to be of ove...
Báo cáo khóa học: Structural properties of the protein SV-IV potx
... compound.
Quantitative analysis of components was performed by
integration of the multiple charged ions of the single species.
For protein analysis, the separation was attained with a
linear gradient of 20–40% solvent ... the monomeric form and 45% in the
trimeric form, and b-structure is absent from both forms.
The CD spectra of the 1–70 and 70–90 regions of the protein
are...
Báo cáo khoa học: Two types of replication protein A in seed plants Characterization of their functions in vitro and in vivo ppt
... the
efficiency of the PCR (Fig. 1B). We performed West-
ern blot analysis of total proteins from seedlings of
wild-type, atrpa70b, and the AtRPA70b RNAi mutant,
and confirmed that very little AtRPA70b protein ... three
independent transformants were isolated for each plasmid pair.
Liquid cultures of each transformant were prepared and tested for
b-galactosidase activity. Shown are...
Báo cáo khoa học: "Discriminative Modeling of Extraction Sets for Machine Translation" pptx
... Conference of the Associa-
tion for Computational Linguistics.
John DeNero and Dan Klein. 2008. The complexity of
phrase alignment problems. In Proceedings of the
Annual Conference of the Association for ... Cherry and Dekang Lin. 2006. Soft syntactic
constraints for word alignment through discrimina-
tive training. In Proceedings of the Annual Confer-
ence of the Associatio...