Báo cáo khoa học: Correlation between conformational stabili

Báo cáo khoa học: Correlation between conformational stability of the ternary enzyme–substrate complex and domain closure of 3-phosphoglycerate kinase potx

... Substrate-assisted domain domain cooperativity FEBS Journal 272 (2005) 1867–1885 ª 2005 FEBS 1885 Correlation between conformational stability of the ternary enzyme–substrate complex and domain closure of 3-phosphoglycerate ... estimated. These correlate well with the increased stability of the ternary complex vs. the binary ones. This increased st...

Ngày tải lên : 16/03/2014, 18:20

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Báo cáo khoa học: "Correlation between ROUGE and Human Evaluation of Extractive Meeting Summaries" pptx

... 5% of the DAs and 16% of the words of the entire meeting. Thus, in total we have 36 human summaries and 24 system summaries on the 6 test meetings, on which the correlation between ROUGE and ... and spoken documents, es- pecially in the meeting domain, for example, the presence of disﬂuencies and multiple speakers, and the lack of structure in spon...

Ngày tải lên : 17/03/2014, 02:20

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Báo cáo khoa học: Correlation between functional and structural changes of reduced and oxidized trout hemoglobins I and IV at different pHs doc

... the interactions between the heme and the surrounding globin, being inﬂuenced by the attached ligand and thereby by the spin state of the iron atom [11]. According to Perutz et al. [18], the region ... in the Q 0 band [25,26]. The splitting of these bands has been regarded as a lowering of the heme symmetry in HbA-CO [17,27], due to nonperpendicular iron–ligand...

Ngày tải lên : 23/03/2014, 12:20

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Báo cáo khoa học: Arginine-induced conformational change in the c-ring ⁄a-subunit interface of ATP synthase ppt

... pocket of the I. tartaricus c-ring. Harmonic restraints were placed on the backbone atoms of the c-ring, with the intention that only the residues of the a subunit and the side chains of the c-ring ... to the outer helix of the c-ring at a dis- tance between helix axes of 12 A ˚ . The longitudinal rotation of the model helix was such that the side c...

Ngày tải lên : 16/03/2014, 06:20

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Tài liệu Báo cáo khoa học: Relationships between structure, function and stability for pyridoxal 5¢-phosphate-dependent starch phosphorylase from Corynebacterium callunaeas revealed by reversible cofactor dissociation studies doc

... in the corresponding pH-rate proﬁles. The pK a values of the cofactor phosphate in unliganded EcMalP and the EcMalP–arsenate complex are 5.6 [26] and 6 .7 [27], respectively. The pK a of the ... in the presence of 5 m M potassium phosphate and potassium sulphate. Reconstitutions with PLP of apo- Cc StP and mutants thereof, and characterization of the wild...

Ngày tải lên : 19/02/2014, 16:20

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Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

... and enzyme–product complexes [29]. On the other hand, k cat ⁄ K m is an apparent second-order rate constant that refers to the properties and the reaction of the free enzyme and free substrate [29]. We have therefore ... of RNase-A in the presence of these amino acids and amino acid derivatives, and values of DG D °, measured in triplicate, are given in Table 1. T...

Ngày tải lên : 07/03/2014, 00:20

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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx

... localized to the N-terminal region, and their speciﬁc functional domains are located in the C-terminal region. The C-lobe of protein kinases mediates the interaction with activators, substrates and ... central domain of MAP2 contain the v-KIND binding core module MAP2 consists of three main structural domains: the cAMP-dependent protein kinase regulatory subunit RI...

Ngày tải lên : 14/02/2014, 19:20

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Tài liệu Báo cáo khoa học: Competition between innate multidrug resistance and intracellular binding of rhodamine dyes pdf

... comparison of rhodamine uptake, in the presence and the absence of uncouplers, allows the estimation of the effect of intracellular binding on the MDR phenomenon. The data detailed obtained in the present ... with the accumulation of dyes, and probably certain drugs, in the cytoplasm. On the other hand, high-afﬁnity binding of these agents to intracellular...

Ngày tải lên : 18/02/2014, 13:20

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Tài liệu Báo cáo khoa học: Interactions between M proteins of Streptococcus pyogenes and glycosaminoglycans promote bacterial adhesion to host cells pdf

... involved in the interaction as the binding of 125 I-labelled DS was reduced to isogenic derivatives of the AP1 strain lacking either of these surface proteins (Fig. 2). The signiﬁcance of the M1 protein ... electrostatic interactions between the negatively charged sulfate groups of the GAG chains and positively charged regions of the ligand. Typi- cally, the...

Ngày tải lên : 20/02/2014, 11:20

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Báo cáo khoa học: Interactions between coenzyme B12 analogs and adenosylcobalamin-dependent glutamate mutase from Clostridium tetanomorphum pot

... energy of the cofactor is sensitive to changes in the pK a of the lower axial base [3]. This has led to speculation that proteins might modulate the pK a of the histidine via the hydrogen bond between ... site [18,19]. The correlation between the distortion of the adenosyl group and cleavage of the cobalt–carbon bond is still not clear. Although the pre...

Ngày tải lên : 07/03/2014, 04:20

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