Báo cáo khoa học: 14-3-3 Proteins regulate glycogen synthase

Báo cáo khoa học: 14-3-3 Proteins regulate glycogen synthase 3b phosphorylation and inhibit cardiomyocyte hypertrophy doc

... NY. 14-3-3 Controls cardiomyocyte hypertrophy through GSK3b W. Liao et al. 1854 FEBS Journal 272 (2005) 1845–1854 ª 2005 FEBS 14-3-3 Proteins regulate glycogen synthase 3b phosphorylation and inhibit ... protein kinase B, PKB) at Ser473 and glycogen synthase 3b (GSK3b) at Ser9, but not extracellular signal-regulated kinase 1 ⁄ 2 (ERK1 ⁄ 2). AdR18-induced PKB a...

Ngày tải lên : 16/03/2014, 18:20

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Tài liệu Báo cáo khoa học: An allosteric DNAzyme with dual RNA-cleaving and DNA-cleaving activities doc

... Hg 2+ [12,13], Pb 2+ [14], and UO 2 2+ [15]; and constructing molecular logic gates and nanomotors [16–20]. How- ever, engineering an allosteric DNAzyme with dual RNA-cleaving and DNA-cleaving activities ... lM L -ascorbate (except for PL–), and 30 mM Hepes at 23 °C. PL+ and PL) represent the presence and absence, respectively, of L-ascorbate in the reaction. Lanes M I and M I...

Ngày tải lên : 16/02/2014, 15:20

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Báo cáo khoa học: Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1⁄TSC2 in C2C12 myotubes pptx

... ERK1 ⁄ 2 phosphorylation was detected rapidly and was tran- sient; phosphorylation of ERK1 ⁄ 2 was induced within 10 min and phosphorylation was back to basal levels by 60 min, unlike phosphorylation ... in phosphorylation states of Akt (T308 and S473 sites) and S6K1 (T389 and T421 ⁄ S424 sites) were determined. (B) Subcellular distributions of TSC1 ⁄ TSC2 proteins were...

Ngày tải lên : 15/03/2014, 11:20

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Báo cáo khoa học: Leishmania donovani phosphofructokinase Gene characterization, biochemical properties and structure-modelling studies doc

... muscle enzyme and the catalytic subunit of S. cerevisiae,andthePP i -depen- dent enzymes of E. histolytica, A. methanolica and P. freundenreichii. Sequences of yeast and human expanding beyond ... and regulatory sites, among the various available structures of E. coli and Bacillus stearothermophilus PFK, as this 4pfk structure contains fructose 6-phosphate and ADP in the active si...

Ngày tải lên : 23/03/2014, 21:21

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Báo cáo khoa học: "High-precision Identiﬁcation of Discourse New and Unique Noun Phrases" docx

... are identified: with and without commas (“Rupert Murdoch, News Corp.’s chairman and chief executive officer,” and “News Corp.’s chairman and chief executive officer Rupert Murdoch”). In the MUC-7 ... discourse and the hearer givenness.The resulting taxonomy is summarised below: brand new NPs introduce entities which are both discourse and hearer new (“a bus”), sub- class of them, b...

Ngày tải lên : 31/03/2014, 03:20

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Tài liệu Báo cáo khoa học: Multiple promoters regulate tissue-speciﬁc alternative splicing of the human kallikrein gene, KLK11⁄hippostasin ppt

... M33S and isoform 1 proteins were secreted into the conditioned media by mouse neuroblastoma, Neuro2a, or COS cells (Fig. 4C and S. Mitsui, unpublished results). The secreted M33S and isoform 2 proteins ... salivary gland; TG, thyroid gland; MG, mammary gland; Pa, pancreas; Lu, lung; Pr, prostate; Te, testis. Fig. 1. Nucleotide sequences of human and mouse KLK11 promoter regions. (...

Ngày tải lên : 19/02/2014, 06:20

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Báo cáo khoa học: Drosophila proteins involved in metabolism of uracil-DNA possess different types of nuclear localization signals pdf

... visualized using excitation and emission wavelengths of 485 and 530 nm, respectively, for YFP, and DAPI ﬂuorescence was visualized by excitation with UV light (355 nm) and detected at 450 nm. The ... Research Fund (OTKA K68229 and CK-78646), the Howard Hughes Medical Institute (55005628 and 55000342), the Alexander von Humboldt Foundation, the National Ofﬁce for Research and Tec...

Ngày tải lên : 15/03/2014, 11:20

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Báo cáo khoa học: LmbE proteins from Bacillus cereus are de-N-acetylases with broad substrate speciﬁcity and are highly similar to proteins in Bacillus anthracis pot

... Automated docking of substrates to proteins by simulated annealing. Proteins 8, 195–202. 40 Goodsell DS, Morris GM & Olson AJ (1996) Auto- mated docking of ﬂexible ligands: applications of auto- dock. ... 140 and 42 using Xtal- View ⁄ Xﬁt [42] and ⁄ or MIFit (Rigaku Americas Corp.). All water and acetate atoms were removed. Hydrogen atoms were added to the crystal structure, an...

Ngày tải lên : 15/03/2014, 11:20

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Báo cáo khoa học: Transcription factor speciﬁcity protein 1 (SP1) and activating protein 2a (AP-2a) regulate expression of human KCTD10 gene by binding to proximal region of promoter pot

... activity of KCTD10; and SP1 and AP-2a can regulate the promoter activity and endogenous KCTD10 expression oppositely through binding this region. Results Analysis of genomic structure and identiﬁcation of ... proliferating cell nuclear antigen and the small subunit of polymerase d, and to have roles in DNA repair, DNA replication and cell-cycle control. To better understand th...

Ngày tải lên : 30/03/2014, 02:20

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Báo cáo khoa học: Increased sensitivity of glycogen synthesis to phosphorylase-a and impaired expression of the glycogen-targeting protein R6 in hepatocytes from insulin-resistant Zucker fa ⁄ fa rats pptx

... was associated with inactivation of glycogen synthase and inhibition of glycogen synthesis. The rate of glycogen synthesis, but not the activity of glycogen synthase, inversely correlated with ... determination of glycogen synthesis and the activities of phosphorylase-a and glycogen synthase. (A) Phos- phorylase-a. (B) Active glycogen synthase versus phosphorylase-a....

Ngày tải lên : 30/03/2014, 11:20

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