Báo cáo khoa học: Protective effect of active oxygen scavengers on protein degradation and photochemical function in photosystem I submembrane fractions during light stress pdf
... assessed in con- nection with alterations in photochemical activity dur- ing strong light illumination of the PSI submembrane fractions. It is concluded from the specificity of the various active oxygen ... FEBS Protective effect of active oxygen scavengers on protein degradation and photochemical function in photosystem I submembrane fractio...
Ngày tải lên: 16/03/2014, 18:20
... combination on iron-induced LDL oxidation in vivo and copper-induced LDL oxidation in vitro Oxidation of LDL observed in iron(II) sulfate-injected rats as measured by thiobarbituric acid reactive ... oxi- dation induced in vivo by the iron(II) ion caused an increase in the anodic mobility of LDL in the case of control rats (Fig. 1). In the case of animals maintained...
Ngày tải lên: 08/03/2014, 08:20
... electron density in the lysine ligand loop is revealed, leading to residues K97 to T101 being modeled with a double main-chain confor- mation. Upon unfolding, dissociation of the lysine ligand ... coordination. Upon titrating increasing amounts of guanidinium hydrochloride (GdmHCl) the protein unfolds resulting in the perturbation of a number of electronic absorption bands and...
Ngày tải lên: 07/03/2014, 17:20
Báo cáo khoa học: The effect of zinc oxide nanoparticles on the structure of the periplasmic domain of the Vibrio cholerae ToxR protein pot
... regulation of protein protein interactions, cellular signal transduction and transcription of DNA [4–7]. Conformational transition, leading to peptide aggregation and the formation of amyloid fibrils, ... amyloid b protein (Ab) [8,9]. Various specific and nonspecific interactions, Keywords nanoparticle protein interaction; protein unfolding by nanoparticle; ToxR protein; Vib...
Ngày tải lên: 23/03/2014, 03:20
Báo cáo khoa học: The effect of ST2 gene product on anchorage-independent growth of a glioblastoma cell line, T98G doc
... mechanisms of their action are still unclear. The expression of cytokines and their receptors in the brain prompted us to investigate ST2 expression and its possible implications in brain tumors. ... autocrine mechanism for the suppres- sion of colony formation (Fig. 5). Finally, we confirmed the inhibitory effect of the ST2 protein on colony formation in soft agar by a...
Ngày tải lên: 31/03/2014, 07:20
Báo cáo khoa học: Biochemical properties of the human guanylate binding protein 5 and a tumor-specific truncated splice variant Mark Wehner and Christian Herrmann doc
... changes in confor- mational flexibility imposed by nucleotide binding, while in the case of hGBP5, conformational restrictions after nucleotide binding and oligomer formation appear to result in strong ... dur- ing changes in the oligomerization state. We observed only a minor in u- ence of the C-terminal truncation on hydrolysis, nucleotide binding and oligomerization of...
Ngày tải lên: 15/03/2014, 10:20
Báo cáo khoa học: Multiple effects of DiS-C3(5) on mitochondrial structure and function pot
... low concentrations preven- ted progression of intrinsic oxygen consumption by mitochondria. However, this effect of DiS-C 3 (5) did not reflect inhibition of the mitochondrial respiratory chain, ... novel effects of DiS-C 3 (5) on mitochondria: (i) inhibition of the Ca 2+ - induced PT by a low concentration of DiS-C 3 (5) and (ii) induction of swelling in the absence o...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: Differential effects of histone deacetylase inhibitors on phorbol ester- and TGF-b1 induced murine tissue inhibitor of metalloproteinases-1 gene expression docx
... and subsequent protein stabilization [37,38]. The proteo- some inhibitor lactacystin inhibited the PMA induction of Timp-1 and no induction was seen in the additional presence of TSA (data not ... expression of Timp-1, only on induced gene expression. In conclusion, this is to our knowledge, the only described instance of HDAC inhibitors having oppos- ite effects on the...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: The heterogeneity of mast cell tryptase from human lung and skin Differences in size, charge and substrate affinity ppt
... a and bI, and at the second locus between bII and bIII, would give rise to nine possible genotypes (aabIIbII, aabIIbIII, aabIIIbIII, abIbIIbII, abIbIIbIII, abIbIIIbIII, bIbIbIIbII, bIbIbIIbIII, ... larger and more intense than those for dimeric tryptase. There was in all cases a corresponding reduction in band size and staining intensity with increasing degree of oligomerizati...
Ngày tải lên: 31/03/2014, 07:20
Tài liệu Báo cáo khóa học: The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain pptx
... rRNA, rendering the ribosome unable to bind elongation factors and hence abolishing protein synthesis [3]. The site of depurination by RTA lies within a highly conserved purine-rich region of 28S ... Trilux liquid scintillation counter. Results N -glycosidase activity of RTA variants containing arginine substitutions RTA variants in which arginyl residues 213 or 258 were substitut...
Ngày tải lên: 19/02/2014, 12:20