Báo cáo khoa học: Principles behind the multifarious control of signal transduction ERK phosphorylation and kinase/phosphatase control potx
Tài liệu Báo cáo khoa học: nsights into the reaction mechanism of glycosyl hydrolase family 49 Site-directed mutagenesis and substrate preference of isopullulanase doc
... IPU consists of a signal sequence (residues 1–19) and a mature part (residues 20–564), and the model is composed of residues 25–540. The overall structure of the model of IPU and the mutated residues ... polysaccharide, pullulan. Comparison of the active sites of the model of IPU and Dex49A The active site structures of t he model of IPU (Fig. 4A) an...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: "Methods for the Qualitative Evaluation of Lexical Association Measures" doc
... (Figures 3 and 4), we find: (i) Examination of 50% of the data in the SLs leads to identification of between 75% (AdjN) and 80% (PNV) of the TPs. (ii) For the first 40% of the SLs, and lead to the worst results, ... fre- quency) and the weak measures ( and ). In the second half of the data in the SLs, how- ever, there is virtually no difference between ,...
Ngày tải lên: 20/02/2014, 18:20
Báo cáo khóa học: Insight into the activation mechanism of Bordetella pertussis adenylate cyclase by calmodulin using fluorescence spectroscopy pptx
... direct exploitation of the structural results of the former to explain the mechanism of CaM activation of the latter. Crystallization and resolution of the 3D structures of AC and AC–CaM, which ... coupling Fig. 5. Binding of Ant-dATP to AC (d) and AC–CaM (m). The degree of binding of the ligand was calculated from the value of the ampli- tude of...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: Bacitracin inhibits the reductive activity of protein disulfide isomerase by disulfide bond formation with free cysteines in the substrate-binding domain pptx
... ring of bacitracin A (937.33). Negative ion mode CID-TOF ⁄ TOF MS analysis of the same precursor yielded the corresponding signature peaks (m ⁄ z 1404.88, 1438.82 and 1470.80) of the other part of ... dis- sected the activities of the various major bacitracin analogs on the reductive activity of PDI, and showed that the H and F analogs are 25-fold more active t...
Ngày tải lên: 14/03/2014, 23:20
Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf
... explain the dimerization of the bc 1 complex at this stage (i.e. just after the addition of ISP and Qcr10p). On the other hand, in the transition from the 500 kDa band to the 670 kDa band, a structural ... bc 1 sub-complex, but the presence of only one of these two subunits does not substitute for the other. After the addition of ISP, the binding of the l...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Shaped by the environment – adaptation in plants Meeting report based on the presentations at the FEBS Workshop ‘Adaptation Potential in Plants’ 2009 (Vienna, Austria) pdf
... Since the discovery of the structure of DNA [4] and the ability to analyse DNA by sequencing and other molecular methods, we now know that genetic variation and epigenetic mecha- nisms form the ... Gallery, London, UK). (B) The colouring of the labellum (specialized median petal) of the flowers of the orchid Ophrys speculum closely resembles the female wasp Co...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: Looking for the ancestry of the heavy-chain subunits of heteromeric amino acid transporters rBAT and 4F2hc within the GH13 a-amylase family ppt
... the lack of domain B protruding out of the TIM barrel in the place of loop 3 connecting the b3-strand to the a3-helix [9,21]. Sharing domain B by rBATs and GH13 enzymes, and especially the sequence of ... extracellular domain. The segments correspond, in fact, with some of the a-amylase family CSRs, namely the b-strands b2, b3, b4 and b8 of the (b ⁄ a) 8...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Acetylcholinesterase from the invertebrate Ciona intestinalis is capable of assembling into asymmetric forms when co-expressed with vertebrate collagenic tail peptide doc
... iden- tify the nature of the enzyme and provide additional information about the evolution of the ChEs, including the origins of the acyl pocket, the T exon, and the asymmetric forms of ChE in the vertebrates. Results The ... illustrates the differences between the construction of the acyl pocket in vertebrate and invertebrate AChEs. The line separa...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: Insights into the structure of plant a-type phospholipase D Susanne Stumpe, Stephan Konig and Renate Ulbrich-Hofmann ¨ ppt
... illustrates the quality of the experimental data (Fig. 2B). Reconstruction of the overall shape of the PLDa2 from the X-ray scattering data was achieved by the ab initio modeling program dammin [24]. The ... nm; and (b) a wide minimum between 208 and 220 nm. The a-helix and b-strand contents of the protein were calculated with the online programs dichroweb [2...
Ngày tải lên: 19/02/2014, 02:20
Tài liệu Báo cáo khoa học: FOXM1c transactivates the human c-mycpromoter directly via the two TATA boxes P1 and P2 docx
... The existence of a protein with the prop- erties of FOXM1c is suggested by the results of Lee et al. [69] who showed that modifications of only the major groove, but not the minor groove, of the ... immune and endocrine systems, components of signaling pathways and of the ubiquitin–proteasome pathway, and genes of tumor viruses. Activation of cell-cycle re...
Ngày tải lên: 19/02/2014, 05:20