Báo cáo khoa học: Three novel carp CXC chemokines are expressed early in ontogeny and at nonimmune sites ppt

... A novel c- N -methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1 Calin B. Chiribau 1 , Cristinel Sandu 1 , ... red anionic flavin semiquinone was formed for more than 99% during the reaction, indicating that the redox potentials of the two couples (oxidized/semiquinone and semiquinone/ hydroquinone) are...

Ngày tải lên: 19/02/2014, 16:20

... adipogenesis. Proc Natl Acad Sci USA 100, 850–855. 39 Ponting CP (1996) Novel domains in NADPH oxidase subunits, sorting nexins, and PtdIns 3-kinases: binding partners of SH3 domains? Protein Sci 5, 2353–2357. 40 ... a solid line and the four SH3 domains are underlined by dotted lines. Ten polyproline motifs that represent poten- tial SH3 binding sites are boxed. (B) Sche- matic...

Ngày tải lên: 16/03/2014, 04:20

... 150 mm; Dionex) and elution using a linear binary gradient: 5–65% ACN in 0.1% formic acid in 35 min, maintenance at 65% ACN for 10 min, and 65–5% ACN in 10 min. The typical operating conditions ... in tropoela- stin participating in covalent linkages that are crucial for the formation of mature elastin [78]. As elastin cross-links are not enzymatically degraded and the s...

Ngày tải lên: 16/02/2014, 14:20

... corresponding to the unbound ligand and to binding sites 1 and 2 are indicated as U, 1, and 2, respectively. The satellite peaks of site 1 and site 2 are also marked. Asterisks indicate exchange ... apo and holo forms of T91C L-BABP indicated that the regions mostly affected by binding are mainly located at the C-terminal part of the protein, at the level of Lys76, Thr81...

Ngày tải lên: 18/02/2014, 06:20

... Major components CipC, Cel9E and Cel48F are indicated; bands analysed using MS methods are numbered; the asterisks indicate a band containing a nonsecreted protein identified by ion-trap MS ⁄ ... [17]. In C. cellulolyticum, the scaffolding protein contains eight cohesin modules that potentially bind to 62 dock- erin-bearing proteins. Previous studies have suggested that any CipC cohesi...

Ngày tải lên: 18/02/2014, 08:20

... proteins, and to the expression of pro- and in ammatory cytokines. There is evidence that the heteromeric guanine nucleotide- binding regulatory protein (G protein) is also involved in TLR4 activation. ... After ligand binding, the receptor undergoes a conformational change. Ligands include hormones, biogenic amines, histamine, serotonin and lipid deri- vates, but also immunological...

Ngày tải lên: 18/02/2014, 13:20

... cases, intense staining of the granulation tissue in the sublining interstitium was evident. Staining of the granulation tissue and lymph aggregates (red arrow) is magnified (Eb). Synovial lining ... inactive RA sections (Fig. 4A), it was intense in VSMC in three distinct active RA sections (Fig. 4Ba– c). In contrast, staining of synovial lining cells and sublining interstitum (F...

Ngày tải lên: 19/02/2014, 16:20

... seems to increase the fraction of Myb species in the insoluble part after subnuclear fractionation, which indicates that sumoylation might be involved in modulating the protein–protein interactions ... sumoy- lation in an in vitro conjugation system shows that c-Myb is a good substrate for SUMO-1 conjugation and that modification of the two sites are interdependent, and (c) a t...

Ngày tải lên: 21/02/2014, 00:20

... nucleotides mediate a reduction in the elongation rate and in uence the accuracy of translation. Early results indicated that (p)ppGpp affect translation by inhibition of elongation factors Tu, Ts and G [17–19]. ... reveals that EF-Ts is an elongated molecule containing four domains: the N-ter- minal domain; the core domain; the dimerization domain; and the C-terminal module [9]. T...

Ngày tải lên: 21/02/2014, 00:20

... September 2009) doi:10.1111/j.1742-4658.2009.07380.x Polypyrimidine tract-binding protein (PTB) is a widely expressed RNA- binding protein with multiple roles in RNA processing, including the splic- ing of alternative exons, mRNA stability, mRNA localization, ... Poly- pyrimidine tract-binding protein promotes insulin secretory granule biogenesis. Nat Cell Biol 6, 207–214. 10 Kosinski PA,...

Ngày tải lên: 07/03/2014, 00:20