... the ratio of guanosine to uridine nucleotide con- centrations on binding of PyrR to BcBL2. The total concentration of nucleotides was held constant at 1 m M. Concentration of nucleotide (l M) K d value ... [24], initiation of sporulation [25], activation of the CodY regulon in nutrient-starved cells [26], and conversion of GTP to ppGpp and pppGpp during the stringent response to...
Ngày tải lên: 16/03/2014, 06:20
... order to coerce our system into accepting only the desired parse tree, we modified it to ac- cept only parses that satisfied bracketed forms. 6. The BSEC has the capability to report on po- ... Precision, and Recall on the next evaluation. REFERENCES Adriaens, G. 1992. From COGRAM to ALCO- GRAM: Toward a Controlled English Gram- mar Checker. Proceedings of the fifteenth I...
Ngày tải lên: 20/02/2014, 21:20
Báo cáo khoa học: Phosphorylation-dependent binding of human transcription factor MOK2 to lamin A⁄C pot
... function of JIP proteins has been previously proposed for two other transcription factors, c-Myc and Max [11]. Inter- estingly, the region of JLP that binds Myc is similar to the region of JSAP1 binding ... in GST–hsMOK2 constructs. Incubation of these fusion proteins with recombinant Aurora A revealed a minor reduction in phosphorylation of the mutant containing only the S146A mutation (...
Ngày tải lên: 07/03/2014, 01:20
Tài liệu Báo cáo khoa học: Interferon-a induces sensitization of cells to inhibition of protein synthesis by tumour necrosis factor-related apoptosis-inducing ligand ppt
... (2004) The up-regulation of human caspase-8 by interferon-gamma in breast tumor cells requires the induction and action of the transcription factor interferon regulatory factor- 1. J Biol Chem 279, ... transla- tion to inhibition by TRAIL. Interferon treatment alone has only a minor effect on protein synthesis but it sensitizes both MCF-7 cells and HeLa cells to the downregulat...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: The subtle side to hypoxia inducible factor (HIFa) regulation pdf
... conditions can be stimulated by various receptor-mediated factors such as growth-factors and cytokines (insulin, insulin-like growth factor 1 or 2, endothelial growth factor, tumour necrosis factor ... period-ARNT-single-minded; CBP, CREB binding protein; CO, carbon monoxide; C-TAD, C-terminal transcriptional activation domain; EGF, epidermal growth factor; eIF-4E, eukaryotic initia...
Ngày tải lên: 20/02/2014, 23:20
Báo cáo khoa học: High negative charge-to-size ratio in polyphosphates and heparin regulates factor VII-activating protease pdf
... protease–inhibitor interactions. Hence, the overall inhibition of FSAP depends not only on the inhibitor but also on the presence of an appropriate co -factor in the vicinity of FSAP. Conclusions The ... units, is stored in platelet-dense granules [10] and released upon platelet activation. PolyP can amplify coagulation by activation of the contact factor pathway, as well as activati...
Ngày tải lên: 07/03/2014, 02:20
Tài liệu Báo cáo khoa học: Secondary substrate binding strongly affects activity and binding affinity of Bacillus subtilis and Aspergillus niger GH11 xylanases docx
... measured. One unit of enzyme activity on Azo-wheat AX (AzU) corresponds to the enzyme concen- tration needed to obtain E 590 = 1.0 after subtraction of the control value (no enzyme) under the conditions ... activity on X 6 (X 6 U) corresponds to the enzyme concentration needed for the formation of 1.0 lm xylotriose from excess X 6 under the conditions of the assay. Secondary substra...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: Exposure of IgG to an acidic environment results in molecular modifications and in enhanced protective activity in sepsis doc
... preparations that differ in the absence or presence of exposure to low-pH conditions during the production process (Endobulin versus Octa- gam). As expected, the binding of the second to fac- tor ... subtracted from the binding to the protein-coated flow cells. biaevaluation software (ver- sion 4.1; Biacore) was used for the calculation of the kinetic rate constants. Calculations we...
Ngày tải lên: 16/02/2014, 15:20
Tài liệu Báo cáo khoa học: Khai thác yếu tố ngôn ngữ trong giảng dạy văn học Việt Nam sau năm 1975 doc
Ngày tải lên: 18/02/2014, 03:20
Tài liệu Báo cáo khoa học: Understanding the binding properties of an unusual metal-binding protein ) a study of bacterial frataxin pdf
... comprises only the evolutionarily conserved domain common to all frataxin orthologs, without addition of mitochon- drial import signals [24]. Although CyaY has similar iron -binding properties to Yfh1 ... homologue mediates mitochondrial iron efflux: evidence for a mitochondrial iron cycle. J Biol Chem 274, 4497–4499. 19 Foury F & Talibi D (2001) Mitochondrial control of iron homeosta...
Ngày tải lên: 18/02/2014, 16:20