Báo cáo khoa học: Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR–/– pdf
Tài liệu Báo cáo khoa học: Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain ppt
... proteinsinvolved in retinoid-related metabolism (retinoic acidreceptors, cellular binding proteins and oxidizing enzymes)have been mapped within the adult dopamine system [35]. In the adult ... in human [9], and by immunohisto-chemistry also in rodents [22].Expression of ADH3 in the adult rodent and human brainOverviews of the expression patterns of the three classes of ADHs in the ... mRNA in the granular layer of human cerebellum. Table 3 compilesour findings in adult brain tissue of all three species.Discussion The distribution of ADHs in the brain is of particularinterest...
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Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf
... repre-sent the last subunits incorporated into the bc1com-plex. On the other hand, the absence of Qcr9p in the DQCR9 ⁄ DQCR10 strain prevented the binding of ISP(Fig. 4B). Interestingly, in the ... addition of ISP and Qcr10p).On the other hand, in the transition from the 500 kDaband to the 670 kDa band, a structural rearrangement of the bc1complex may occur due to the binding of ISP and ... comparable amounts in both yeast strains. Therefore, the reason for the disap-pearance of the bc1dimer in the yeast strain in whichQcr10p is missing remains unknown.On the basis of all the above...
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Tài liệu Báo cáo khoa học: Looking for the ancestry of the heavy-chain subunits of heteromeric amino acid transporters rBAT and 4F2hc within the GH13 a-amylase family ppt
... barrel domain,including domain B and the C-terminal domain C forrBAT proteins (669 residues on average); (b) the cata-lytic TIM barrel domain, including domain B and the C-terminal domain C for ... is the lack of domain B protruding out of the TIM barrel in the place of loop 3 connecting the b3-strand to the a3-helix [9,21]. Sharing domain B by rBATs and GH13 enzymes, and especially the ... in region I covering the b3-strand; (b) a segment of up to five residues(307_GVDGF in human rBAT) preceding the func-tional arginine (arginine 197 in oligo-1,6-glucosidase) in region II of the...
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Tài liệu Báo cáo khoa học: Acetylcholinesterase from the invertebrate Ciona intestinalis is capable of assembling into asymmetric forms when co-expressed with vertebrate collagenic tail peptide doc
... with the PRAD domain of ColQ indicates that the WAT domain of the C. intestinalis AChE is capable of organizing the sub-units into a tetramer through interaction with the PRAD domain of ColQ. The ... fromC. intestinalis expressed in vitro and nativeenzyme expressed in vivo indicates the enzymeis AChETo determine the nature of the cholinesterase activity of the recombinant C. intestinalis ... vertebrate and invertebrate AChEs. The line separates the vertebrate and invertebrate AChEs. The numbers at the top of the figure correspond to the amino acids in T. californica. In the vertebrates, the...
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Tài liệu Báo cáo khoa học: Insights into the structure of plant a-type phospholipase D Susanne Stumpe, Stephan Konig and Renate Ulbrich-Hofmann ¨ ppt
... similar-ity in the remaining parts of the molecules. Most mam-malian PLDs contain a PX and a PH domain instead of the C2 domain in plants, whereas microbial PLDslack such probably regulatory domains.Despite ... responsible for the calcium binding [8], we hypothesize that this bind-ing event takes place at the C2 domain.A second calcium-binding site of lower affinity at the C2 domain (corresponding to the dissociationconstant ... to the binding of cal-cium ions to the enzyme, and not (or not only) to bet-ter structuring of the substrate aggregates.From both the CD and the activity data, two differ-ent calcium-binding...
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Tài liệu Báo cáo khoa học: Hypoxia reduces the expression of heme oxygenase-2 in various types of human cell lines A possible strategy for the maintenance of intracellular heme level pdf
... hypoxia on HO-1 and HO-2 expression in human cell linesWe initially analyzed the effects of hypoxia on the expression of HO-1 and HO-2 in human cell lines of bone marrow origin, including KG1 myeloid ... the intensity for the a-tubulin signal. Shown are the relativeexpression levels of HO-1 and HO-2 proteins in YN-1 cells (B) and those of HO-2 protein in K562 cells (D). The intensity representing ... C). Other conditions are described in Fig. 1B. The intensities of the signals in (A) and (C) were quantified, and the intensity representing HO-1 or HO-2 protein was normalized with respect to the...
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Tài liệu Báo cáo khoa học: Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina doc
... activity in crude yeastextract as the untagged protein, indicating that the tagwas not interfering with the protein activity. The tagged protein was purified and then used for furtheranalysis. In the ... nkatÆmg)1. The GLD1 pro-tein was tagged with a histidine tag at the N-terminalend by adding the coding sequence for six histidines to the end of the open reading frame, and then expressed in S. ... The tagged protein had a similar activ-ity in the crude extract as the nontagged protein, indi-cating that the tag did not affect the protein activity. The tagged protein was then purified and...
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Tài liệu Báo cáo khoa học: nsights into the reaction mechanism of glycosyl hydrolase family 49 Site-directed mutagenesis and substrate preference of isopullulanase doc
... 20–564), and the model iscomposed of residues 25–540. The overall structure of the model of IPU and the mutated residues in this study areshown in Fig. 3. To elucidate the mechanism of the substrate ... of 3.2) [45] was a solution in the Dali result. It islikely that the inte rface between N-terminal and b-he licaldomains participate in binding of the polysaccharide,pullulan.Comparison of ... 372, and 373are the potential catalytic r esidues of I PU. Also, Trp425 of Dex49A, which is the corresponding residue of Trp402 of IPU, is reportedly located in the vicinity of the active siteand...
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Tài liệu Báo cáo khoa học: An immunomodulator used to protect young in the pouch of the Tammar wallaby, Macropus eugenii pptx
... activa-tion of CCK receptors stimulate production of inter-leukins and secretion of immunoglobulins on the mucosal surface of the intestine [49,50]. The antibacte-rial defence of the intestinal mucosa ... reduced the response to euge-nin, indicating that eugenin is indeed acting throughCCK2receptors.To further investigate the interaction of eugenin withCCK2receptors, we investigated the effect ... the sequence after the Tyr(SO3) residue of eugenin is different from those of the other mammalian and amphibian analogues shown in Table 1.CCK-8 and caerulein bind to CCK receptors [42].There...
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Tài liệu Báo cáo khoa học: Insights into the interaction of human arginase II with substrate and manganese ions by site-directed mutagenesis and kinetic studies Alteration of substrate specificity by replacement of Asn149 with Asp docx
... known to be involved in binding and hydrolysis of the guanidino group of l-arginine by arginase are strictly conserved in the act-ive site of the agmatinases [19]. Moreover, modelingstudies ... byagmatine hydrolysis, in studying the inhibitory effect of agmatine on arginine hydrolysis, reactions were followedby measuring the formation of ornithine, determined by the method of Chinard ... the activesites of this enzyme and arginase I. In spite of the rel-atively low agmatinase activity of the Asn149Asp vari-ant, it is clear that the interactions of arginase II withl-arginine...
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Từ khóa: Một số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDENghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Thơ nôm tứ tuyệt trào phúng hồ xuân hươngTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)QUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ