Báo cáo khoa học: Protection of chylomicron remnants from oxidation by incorporation of probucol into the particles enhances their uptake by human macrophages and increases lipid accumulation in the cells ppt

... cell induction by chylomicron remnants (Eur. J. Biochem. 271) 2427 Protection of chylomicron remnants from oxidation by incorporation of probucol into the particles enhances their uptake by human macrophages ... the protection of chylomicron remnants from oxidation enhances, rather than inhibits, their induction of lipid accumu...

Ngày tải lên: 16/03/2014, 16:20

... disease, thereby providing the missing data. The phenotype of XLA and the potential of BTK and ITK inhibitors The outcome of defective BTK signaling in humans has been described previously in detail ... directly involved in ligand binding, presumably abolishing the interaction with signaling partners. The remaining mutations alter amino acids located outside the...

Ngày tải lên: 14/02/2014, 18:20

... conformation, the SH2 domain binds to pY i on the C-terminal tail, and the Src homology 3 (SH3) domain binds to the linker between the SH2 and kinase domains at the back of the small lobe, preventing the ... in (B) show the time point of step changes in [RPTP]. The corresponding [RPTP] values, 117.5, 126.5 and 135.5 n M, are indi- cated by dashed lines 1–3...

Ngày tải lên: 18/02/2014, 11:20

... mechanism of rhodamine dyes, agents allowing the enhanced uptake of rhodamine dyes inhibited the efflux of these dyes from the cells. The efflux of rhodamine 123 and TMRM was inhib- ited by NBD-Cl and ... including the dye adsorbed to the sur- face of the cells. To avoid complication of the uptake studies by active pumping of the dyes into the...

Ngày tải lên: 18/02/2014, 13:20

... : 2000 in blocking solution for 30 min. Cells were rinsed in NaCl ⁄ P i several times and incubated in blocking serum containing anti-mouse IgG (Vectastain) for a fur- ther 30 min. Staining was ... more rapid handling using the devices and loss of peptide on the column resin. The only detriment of the peptides produced here is the fact that they contain an exo- genou...

Ngày tải lên: 18/02/2014, 13:20

... domain structure. Schematic of Vrp1p showing the Vrp1p truncations and mutant proteins used in this study and their various known domains: actin-binding domains, Hof one trap (HOT) domain, and LBD. ... novel actin-binding VH2-C domain in C-Vrp1p 364)817 may explain why mutations in the N-terminal actin-binding WH2 domain (WH2-1) or even deletion of the entire N-termina...

Ngày tải lên: 18/02/2014, 16:20

... derived from the human KLK11 gene We determined the nucleotide sequences of 15 clones of the PCR products from the human prostate by oligo cap RACE in order to determine the transcrip- tion initiation ... the regulation and characteristics of these isoforms are unknown. We identified the first three exons (1a, 1b, and 1c) by determining their transcriptio...

Ngày tải lên: 19/02/2014, 06:20

... from D -pantothenate. The Dfp flavoprotein catalyzes the synthe- sis of the coenzyme A precursor 4¢-phosphopantetheine from 4¢-phosphopantothenate and cysteine using the cofac- tors CTP and flavine mononucleotide ... conserved in CoaB proteins. Residues of the N-terminal part of the Escherichia coli CoaB domain that are conserved in CoaB (Dfp) proteins from all k...

Ngày tải lên: 19/02/2014, 12:20

... because in terms of func- tion, the fish intestine is highly regionalized both in the larva and in the adult [38]. The posterior segment of the fish intestine is the absorption site of intact pro- teins, ... and in epithelial cells lining the digestive tract lumen [43,44]. Considering the importance of the intestinal barrier in the process of oral p...

Ngày tải lên: 19/02/2014, 16:20

... (F340) increases, whereas the fluorescence intensity at 380 nm (F380) decreases upon the binding of Ca 2+ . The change in the ratio of F340 ⁄ F380 determined the change in Ca 2+ concentration inside ... Ca 2+ ⁄ CaM-binding IQ domain that is involved in the activa- tion of Ras-GRF1. Stimulation of all the splice variants of the G s -coupled serotonin receptor 5-...

Ngày tải lên: 19/02/2014, 18:20