Báo cáo khoa học: Membrane binding of SRP pathway components in the halophilic archaea Haloferax volcanii docx

... interaction of SRP pathway components in Archaea, the membrane binding of SRP5 4 and FtsY in the halophilic archaea Haloferax volcanii was investigated. Such studies offer insight not only into the membrane- associating ... presently of the nature of the FtsY membrane interaction in Archaea. Moreover, the steps leading to deliveryofSRPtothearch...

Ngày tải lên: 16/03/2014, 16:20

... attached to the lamina by integral membrane proteins of the INM. The INM proteins form complexes, transiently or stably, with lamins, chromatin proteins and a vari- ety of regulatory proteins, including ... emerin. Emerin is the product of a gene linked to EDMD [19,21]. An integral membrane protein specifically loca- ted at the inner nuclear membrane, emerin, like other IN...

Ngày tải lên: 07/03/2014, 12:20

... strains revealed the presence of a single point mutation in 1337 nucleotides of BmIVD. In the sku mutant, the 1127th guanine from the start codon was substituted by thymine and none of the other sites ... acts in the third step of leucine degradation and the sku mutant accumulates branched-chain amino acids in haemolymph, this mutant may be useful in the inve...

Ngày tải lên: 18/02/2014, 04:20

... chemokines stimu- lated mainly by in ammatory cytokines, including IL-1b, TNF-a and IFN-c. (B) Chemokines expressed in the joint recruit leukocytes into the joints. In addition to functioning in ... a G-protein that transduces the intracellular signal. The two major subclasses include the CC chemokines (where the cysteines are neighboring) and the CXC chemokines (where t...

Ngày tải lên: 18/02/2014, 18:20

... position. In the struc- tural deviation, the solvent ASA of the side-chain of His210 increased with the decrease in size of the side-chain at residue 169 (Table 1 and Fig. 3A). However, the ASAs of Asp113 ... size of the side-chain at residue 169 and the pK 2 showed a clear linear relationship (Fig. 3B). The pK 2 increased as the size of the residue at po...

Ngày tải lên: 21/02/2014, 03:20

... localization of the laminin binding protein As a part of molecular mechanism underlying the invasion of the extracellular matrix of solid organs like liver and spleen, a laminin binding component ... the case of indirect immunoblotting, signals could be detected only in the supernatant containing the 27-kDa part, implying thereby the presence of laminin bindin...

Ngày tải lên: 21/02/2014, 00:20

... to gain further insight into the binding mode of different carbohydrates (cellobiose, cellotetraose and cellohexaose) to the binding pocket of the family 11 CBM. The crystal structure of C. thermocellum ... 1III–V), which could indicate that the corre- sponding hydroxyl groups are involved in protein binding. The results for the linebroadening measurements of prot...

Ngày tải lên: 18/02/2014, 17:20

... corresponded to that obtained in the absence of tHSA–heme-Fe(III) (l 0 = 2.4 · 10 )1 s )1 ). Ibuprofen binding to tHSA–heme-Fe(II)-NO Figure 4 shows the binding isotherm for ibuprofen binding to tHSA–heme-Fe(II)-NO. ... December 2010) doi:10.1111/j.1742-4658.2010.07986.x The ibuprofen primary binding site FA3–FA4 is located in domain III of human serum albumin (HSA), th...

Ngày tải lên: 06/03/2014, 01:20

... 2009 The Authors Journal compilation ª 2009 FEBS 235 A B C D 0 min 2 min 10 min 30 min 0 min 2 min 10 min 30 min 0 min 2 min 10 min 30 min 0 min 2 min 5 min 30 min 0 min 10 min 20 min 30 min 0 min ... how the pattern of substitution can contribute to the orientation, either sn-1orsn-2, of the insertion of the DAG lactone into the binding cleft of the C1 domain [9]. Th...

Ngày tải lên: 15/03/2014, 09:20

... localized to the interior of the ER in cells, it, together with the luminal CAT, provides an easily quantifiable (via assay) and unambiguous 5 reporter of the entry of fatty acylcarnitine into the ER ... shows a linear plot of [ 3 H]carnitine uptake at equilibrium (60 min values) vs. the L -carnitine concentra- tion. The slope of this line, which represents the Ôcar...

Ngày tải lên: 16/03/2014, 16:20