Báo cáo khoa học: Fifty years of muscle and the sliding filament hypothesis pdf

... skeletal muscle. Nature 375, 688–691. Ó FEBS 2004 Fifty years of muscle and the sliding filament hypothesis (Eur. J. Biochem. 271) 1415 REVIEW ARTICLE Fifty years of muscle and the sliding filament hypothesis Hugh ... Laboratory, USA. Scale of the machine can be judged from automobiles and tractor- trailers on left-hand side of photographs. Ó FEB...

Ngày tải lên: 16/03/2014, 16:20

... USA) and Anna Tramontano (University of Rome, Italy) with the invaluable help of Andriy Kryshtafovych (Lawrence Livermore National Laboratory) and Volker Eyrich (Columbia University). The goals of ... can best be focused. The scheme is simple: the organizers collect sequences of ‘targets’ i.e. of pro- teins, the structure of which are likely to be solved within a few...

Ngày tải lên: 07/03/2014, 16:20

... experimental condition were built and then compared; spots were quanti- fied on the basis of their relative volume (spot volume nor- malized to the sum of the volumes of all the representative spots) and those that ... apoptosis and induces the synthesis of antioxidants [22]. Alterations in mitochondrial proteins, on the other hand, are specifically linked to one of...

Ngày tải lên: 15/02/2014, 01:20

... charac- teristic of the DNA. We determined a direct correlation between exonuclease activity of APE1 and the thermal stability of DNA duplexes. The efficiency of the removal and the thermal stability of DNA ... investigated. The monolayer was wounded in the presence of different concentrations of glu- cose with and without these compounds and the recovery...

Ngày tải lên: 19/02/2014, 07:20

... details of these signaling events have yet to be investigated, many of the molecular interactions down- stream of the Eph and ephrin molecules appear to lead to the regulation of the cytoskeleton of ... underlined. (B) SDS/PAGE of each purification step of the expressed SH2 domain of Grb4. Lane 1: the soluble part of the cell lysate; Lane 2: the insoluble pa...

Ngày tải lên: 19/02/2014, 12:20

... signi- ficantly affect the binding of exogenous ligands, such as the cyanide anion, to the Fe(III) complex [17], and O 2 and CO to the Fe(II) complex [18]. H owever, the PDE activities of these mutants ... subtle differences in the spectral maxima in the visible region of the Fe(III) species, spectra of the Asp40 mutants were essentially similar to that of the...

Ngày tải lên: 19/02/2014, 16:20

... unstable than the mammalian enzymes. The catalytic properties such as the effects of pH, ionic strength and m etal ions on the activity, o f the purified shark DNase I resembled those of the other vertebrate ... produce the thermally stable form of the higher vertebrates [18]. Therefore, with regard to the genesis of the DNase I e nzyme present in higher vertebrat...

Ngày tải lên: 19/02/2014, 16:20

... over magistrates, death, and suicide, and a VP over labeled, and then com- bine the trees by placing one under the other at each step, and finally create an S node at the root. C&C-CONV has ... correlation, and the spread on the line x = 100, supports the theory that these sentences are not necessarily easier to parse, but rather have fewer annotation inconsistencies....

Ngày tải lên: 19/02/2014, 19:20

... structure of the protein. Figure 2 shows the fluorescence spectra of wild-type SNase and the four mutants E142O, K133A, W140A and W140O. The fluorescence spectra of E142O and K133A are similar to that of ... analysis of protein unfolding The DSC curves of the wild-type protein and the mutants K133A, E142O, W140A and W140O are shown in Fig. 3, with their therm...

Ngày tải lên: 20/02/2014, 01:20

... contributions to the 17 O-NMR linewidth (DW) were obtained by subtracting the width of the H 2 17 O signal in the presence of HSA from the width of the H 2 17 O signal in the presence of Mn(III)heme–HSA ... [19,21,31]. Additionally, the affinity of Mn(III)heme for HSA and the spectroscopic properties of the Mn(III)heme–HSA adduct in the presence of myrista...

Ngày tải lên: 20/02/2014, 02:22