Báo cáo khóa học: Crystal structure of the chi:psi subassemb

Tài liệu Báo cáo khoa học: Crystal structure of importin-a bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 ppt

... exception to this is the location of the amide group of Lys204 at P3, where there is a break in the main-chain density at the 2.8r map level. The corresponding position in the apo structure ... primarily occurs by the formation of a hydrogen bond between the side-chain hydroxyl group of Tyr205 and the importin-a main chain at the C-terminus of the ARM1 H3 hel...

Ngày tải lên : 14/02/2014, 19:20

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Tài liệu Báo cáo khoa học: Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability pdf

... the ter- tiary structure of ApeSOD has not been elucidated. In the present study, for the ﬁrst time, we describe the crystal structure of ApeSOD. In particular, we focus on the coordination of ... [26]. These ﬁndings lead to the hypothesis that Fe-bound ApeSOD mimics the product-inhibited form and the shift of Tyr39 sup- presses the release of the peroxide...

Ngày tải lên : 14/02/2014, 22:20

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Tài liệu Báo cáo khoa học: Crystal structure of Klebsiella sp. ASR1 phytase suggests substrate binding to a preformed active site that meets the requirements of a plant rhizosphere enzyme doc

... Thus, the differences between wild-type and mutant structure are in the same range as the differences between the two molecules of the asymmetric unit of the wild-type structure. Neither the ... to determine the structure of the complex of an inactive PhyK mutant with its substrate phytase, the reﬁned structure of the wild-type enzyme was used for mo...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family pptx

... according to the residue in the mid- point of the respective loop, as shown in Fig. 2. To the east of the active site the 37- and 60-loops border the S2¢ pocket of the proteinase. The observed ... reveals that the most similar regions of these proteinases medi- ate interaction of the two b-barrels, formation of the catalytic machinery and structures require...

Ngày tải lên : 19/02/2014, 00:20

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Tài liệu Báo cáo khoa học: Crystal structure of the BcZBP, a zinc-binding protein from Bacillus cereus doc

... determines the shape of the active site entry. (e) The structure of the active site is essentially identical with the active sites of the MshB and LpxC proteins. The conservation of catalytically important ... diagram. B A Fig. 1. Structure of the BcZBP dimer. (A) Topology diagram of the dimer drawn with the program TOPDRAW [34]. The relative orienta- tio...

Ngày tải lên : 19/02/2014, 00:20

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Tài liệu Báo cáo khoa học: Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid doc

... on the other hand involving the C-terminal part of the polypeptide chain (Fig. 7). In the latter, differences in the conformation of the loop between Fig. 6. Stereo picture of the model of the a-carbanion/enamine ... catalytic residues The active site cavity in IPDC extends from the thiazolium ring of the cofactor to the surface of the protein. The entr...

Ngày tải lên : 20/02/2014, 11:20

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Báo cáo khoa học: Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product L-glutamate and its activator Tris pdf

... report the crystal structure of the intact glutaminase under four different conditions: in the absence of the additives (referred to as N); in the presence of Tris (referred to as T); in the presence ... twofold axis of crystallographic symmetry. The two independent physiological dimers shared a similar structure. The physiological dimer of the TG structure...

Ngày tải lên : 06/03/2014, 09:22

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Báo cáo khoa học: Crystal structure of the parasite inhibitor chagasin in complex with papain allows identiﬁcation of structural requirements for broad reactivity and speciﬁcity determinants for target proteases pptx

... part, and (b) the variability of the angle of approach of the inhibitor relative to the catalytic cleft of the enzyme. The latter factor may reﬂect not so much the geometry of the catalytic site ... Considering the stability of the chagasin structure, the similarity or dissimilarity of its complexes with various enzymes may be regarded as the result of...

Ngày tải lên : 16/03/2014, 04:20

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Báo cáo khoa học: Crystal structure of the tetrameric inositol 1-phosphate phosphatase (TM1415) from the hyperthermophile, Thermotoga maritima docx

... In the center there is a schematic of the mutual relationship of the monomers, in selected members of the family, as indi- cated by the twist angle of the dimer. TM1415 constitutes one of the ... nonarchaeal IMPases. The superposition of the second subunit of the MJ0109 structure (1G0H) after superposition of the ﬁrst subunit requires a rotation of ...

Ngày tải lên : 16/03/2014, 11:20

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Báo cáo khóa học: Crystal structure of the chi:psi subassembly of the Escherichia coli DNA polymerase clamp-loader complex doc

... FEBS 2004 E. coli DNA polymerase clamp-loader subassembly (Eur. J. Biochem. 271) 449 Crystal structure of the chi:psi subassembly of the Escherichia coli DNA polymerase clamp-loader complex Jacqueline ... archaebacteria] that tether the DNA polymerase to DNA [2]. The interaction between the DNA polymerase and the sliding clamp enables t...

Ngày tải lên : 16/03/2014, 16:20

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