Báo cáo khoa học: Methylene analogues of adenosine 5¢-tetraphosphate Their chemical synthesis and recognition by human and plant mononucleoside tetraphosphatases and dinucleoside tetraphosphatases pot
Báo cáo khoa học: Methylene analogues of adenosine 5¢-tetraphosphate Their chemical synthesis and recognition by human and plant mononucleoside tetraphosphatases and dinucleoside tetraphosphatases pot
... adenosine 5¢-tetraphosphate Their chemical synthesis and recognition by human and plant mononucleoside tetraphosphatases and dinucleoside tetraphosphatases Andrzej Guranowski 1 ,El _ zbieta Starzyn ´ ska 1 , ... pCH 2 pCH 2 pA. Synthesis of adenosine- 5’-[a,b,b, c-bis (methylene) ]- tetraphosphate, ppCH 2 pCH 2 pA. Synthesis of adenosine- 5’-[a,b;c,d-...
Ngày tải lên: 16/03/2014, 14:20
Tài liệu Báo cáo khoa học: The mechanism of a-proton isotope exchange in amino acids catalysed by tyrosine phenol-lyase doc
... EA D is off the reaction pathway responsible for the principal transformation. Values of K SH and k f(H) correspond to K D and k f for the reaction of nondeuterated substrate, and K SD , k f(D) and k r(D) are ... kinetics of quinonoid intermediate formation for the reactions of TPL with L -phenylalanine, L -methionine, and their a-deuterated analogs in D 2 O, and compare...
Ngày tải lên: 19/02/2014, 16:20
Báo cáo khoa học: Definition of the residues required for the interaction between glycine-extended gastrin and transferrin in vitro pptx
... presence of increasing concentrations of unlabeled Ggly. The ApoTf–Ggly complex was separated from the unreacted Ggly by SDS ⁄ PAGE, and the extent of incorporation of radioactivity was determined by ... of ferrous ions from the enterocyte by ferro- portin and their oxidation to ferric ions by hephaes- tin, circulating Gamide or Ggly might act as chaperones for the upt...
Ngày tải lên: 07/03/2014, 02:20
Báo cáo khoa học: The role of interface framework residues in determining antibody VH ⁄ VL interaction strength and antigen-binding affinity pptx
... diagnostics and therapy, primarily because of their relative ease of production by many systems, including microbial culture. However, because of their heterodimeric domain structure and weak heavy ... display modes enables side -by- side evaluation of antigen-bind- ing ability and V H ⁄ V L interaction strength of the tar- get Fv, and also rapid screening of Fv that...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: " The Development of Lexical Resources for Information Extraction from Text Combining Word Net and Dewey Decimal Classification" potx
... (hundreds to thousands of words) and most lexical information is not transportable across domains. The problem of lexicon transport is worsened by the growing degree of lexicalization of IE systems: ... ontology. This map- ping between words and ontology is generally to be built by hand. Most of the time in transport- ing the lexicon is spent in identifying and buil...
Ngày tải lên: 08/03/2014, 21:20
Báo cáo khoa học: High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1 pot
... characterized by the ratio of m app , determined by gel filtration chromatography, and the absolute value of m, calculated from the amino acid sequence of the protein. NMR spectroscopy 1 H-NMR spectra of ... (2004) The role of structural disorder in the function of RNA and protein chaper- ones. FASEB J 18, 1169–1175. 28 Li SS (2005) Specificity and versatility of SH3 an...
Ngày tải lên: 16/03/2014, 02:20
Báo cáo khoa học: Functional characterization of artemin, a ferritin homolog synthesized in Artemia embryos during encystment and diapause doc
... characteristic of molecular chaperones and shown here to be shared by apoferritin and ferritin. This is the first report that apoferritin ⁄ ferritin may protect cells from stress other than by iron sequestration. ... vitro,a capability shared by apoferritin and ferritin, and con- fers stress tolerance on transfected mammalian cells. Artemin and ferritin may have arisen from t...
Ngày tải lên: 16/03/2014, 11:20
Báo cáo khóa học: Identification of a gene encoding Lon protease from Brevibacillus thermoruber WR-249 and biochemical characterization of its thermostable recombinant enzyme pptx
... relative volume of a protein occupied by aliphatic side chain. On the other hand, Bt-Lon is characterized by a higher content of V (56 vs. 48), P (33 vs. 28), and E (84 vs. 76) and by a lower content of G ... promoter region of Bt-lon. Potential )35 and )10 regions and the RBS are underlined. The )16 region is bold underlined. An inverted repeat of dyad symmetry is box...
Ngày tải lên: 16/03/2014, 16:20
Báo cáo khoa học: Solution structure of 2¢,5¢ d(G4C4) Relevance to topological restrictions and nature’s choice of phosphodiester links docx
... characterized by featu res of both A and BDNA. Possible implications of this on the topological restrictions of 2¢,5¢ DNA, and its rejection by nature, are discussed. Materials and methods DNA synthesis and ... uanti- tation of anomeric effect in adenosine and guanosine by comparison of th e thermodynam ics of the p seudorotational equilibrium of the pentofura...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons ppt
... 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons. Glia 49, 15–23. 3 Guillemin GJ, Wang L & Brew BJ (2005) Quinolinic acid selectively induces apoptosis of human ... formation of NO• by the activation of nNOS. Highly reactive free radicals are formed, which can cause oxidative damage to DNA lead- ing to over-activation of P...
Ngày tải lên: 22/03/2014, 21:20