Báo cáo khoa học: Cartducin stimulates mesenchymal chondroprogenitor cell proliferation through both extracellular signal-regulated kinase and phosphatidylinositol 3-kinase⁄Akt pathways pot
... Cartducin stimulates mesenchymal chondroprogenitor cell proliferation through both extracellular signal-regulated kinase and phosphatidylinositol 3 -kinase Akt pathways Hironori ... cartducin- stimu- lated proliferation of mesenchymal chondroprogenitor cells. Our results indicated that cartducin initiates MAPK and PI3K signaling cascades in mesenchymal...
Ngày tải lên: 16/03/2014, 13:20
... protons and protons from a, b and c positions of 3-hydroxy fatty acids are marked with; -CH ¼ CH-, -CH 3 ,and- CH 2 -, a, b and c, respectively. CHCl 3 ,DMSOandH 2 O represent signals from solvents and ... Darvill, A.G., McNeil, M., Stevenson, T.T. & Albersheim, P. (1985) Isolation and characterization of plant cell walls and cell wall components. Methods Enzymol. 118, 3–...
Ngày tải lên: 07/03/2014, 15:20
... protein kinase signaling pathways, which in turn activates SREBP processing. It has been reported that glutamine stimulates Akt phosphorylation in HepG2 cells [21] and both phosphatidylinositol 3 -kinase ... cells and Caco-2 cells were plated in 12-well plates at a density of 1.0 · 10 5 cellsÆwell )1 , cultured with DMEM for 20 h, and then transfected with 200 ng of one of the...
Ngày tải lên: 28/03/2014, 22:21
Báo cáo khóa học: Ouabain stimulates endothelin release and expression in human endothelial cells without inhibiting the sodium pump Robert Saunders and Georgios Scheiner-Bobis pptx
... medium (ECGM; Promocell, Heidelberg, Ger- many) and transferred to a gelatin-coated, 94-mm cell culture dish. After 4 h, the medium and any nonadherent cells were aspirated and the medium replaced. ... smooth muscle cells of the artery. As this substance is a potent vasoconstrictor and growth promoter of vascular smooth muscle cells via the ET A receptor, and because vesicular fus...
Ngày tải lên: 30/03/2014, 13:20
Báo cáo khoa học: "Effect of intern’s consecutive work hours on safety, medical education and professionalism"
... medical education and professionalism Christopher P Landrigan, Steven W Lockley and Charles A Czeisler Division of Sleep Medicine, Boston, Massachusetts, USA Corresponding author: Christopher P Landrigan, clandrigan@rics.bwh.harvard.edu Published ... to be tested, and should be a major focus of future work. Authors’ response Eric B Milbrandt, Babak Sarani and Louis H Alarcon We would...
Ngày tải lên: 25/10/2012, 10:45
Tài liệu Báo cáo khoa học: P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity pptx
... cells and decreased in a-syn-expressing cells compared to control-transfected cells. (E) Quantification of the surface DAT bands in (B) normalized against b-actin as analyzed by densitometry and ... preferentially expressed in oligodendrocytes, and is present in both the cell body and myelin sheets [12,31], and its putative functions related to microtubules and vesicle transpor...
Ngày tải lên: 14/02/2014, 21:20
Tài liệu Báo cáo khoa học: Diol dehydratase-reactivating factor is a reactivase – evidence for multiple turnovers and subunit swapping with diol dehydratase pdf
... c, e, and g). To determine their subunit compositions, bands i–vi were excised and subjected to SDS⁄ PAGE on 6% and 14% gels (Fig. 5B,C), followed by densito- metric analyses. Both band i and band ... of ADP and Mg 2+ and followed by nondenaturing PAGE, the bands of the enzyme and the reactivase were markedly reduced in density, and two bands of the enzymeÆreactivase complex...
Ngày tải lên: 15/02/2014, 01:20
Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer ppt
... functional domains: an extracellular ligand-binding domain; a transmembrane domain; an intracellular tyrosine kinase domain; and a C-terminal regulatory domain [2]. The extracellular domain is subdivided ... mul- tiple signalling pathways, including mitogen-activated protein kinase, phosphatidylinositol 3 -kinase ⁄ AKT and the signal transducer and activator of transcription...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development doc
... morphogenesis, in particular proliferation, differentiation, cell cycle regulation, and apoptosis [11,45,46]. Through suppression of genes inducing terminal differentiation, apoptosis, and AP-2 proteins ... chondrocyte hypertrophy [57]. Mice lacking both Runx2 and Runx3 do not have hypertrophic chondrocytes or type X collagen-express- ing cells, showing that both Runx2 and Ru...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Proteolysis of Pseudomonas exotoxin A within hepatic endosomes by cathepsins B and D produces fragments displaying in vitro ADP-ribosylating and apoptotic effects doc
... conjunctiva epithelial Chang cells [38] and J774A.1 macrophages [39] through the type III secretion system. Also, ETA-induced human mast cell apoptosis by activation of the caspase-8 and caspase-3 pathways and downre- gulation ... reconstitution of the cytotoxic pathways with in vitro cytosol and cell- free mitochondria, our data suggest a direct interaction between ETA and...
Ngày tải lên: 18/02/2014, 04:20