Báo cáo khoa học: Coiled–coil interactions modulate multimerization, mitochondrial binding and kinase activity of myotonic dystrophy protein kinase splice isoforms pptx
Báo cáo khoa học: Coiled–coil interactions modulate multimerization, mitochondrial binding and kinase activity of myotonic dystrophy protein kinase splice isoforms pptx
... Journal compilation ª 2006 FEBS
Coiled–coil interactions modulate multimerization,
mitochondrial binding and kinase activity of myotonic
dystrophy protein kinase splice isoforms
Rene
´
E. M. A. van ... domain
modulates myotonic dystrophy protein kinase multimerization, substrate
binding, kinase activity and subcellular localization characterist...
Tài liệu Báo cáo khoa học: Dmrt1 genes at the crossroads: a widespread and central class of sexual development factors in fish pdf
... initial molecu-
lar activity of Sry is translated into cellular structure
and organ morphology. Interestingly, Dmrt1, the
ancestor of Dmrt1bY, is one of the downstream effec-
tors of Sry in the male ... prototype members of this group of
factors are the Drosophila doublesex (dsx) and Caenor-
habditis mab-3 genes. The Dmrt group of molecules is
characterized by a conserved...
Tài liệu Báo cáo khoa học: Tet repressor mutants with altered effector binding and allostery docx
... effector of TetR known so far. The DNA
fragments containing the randomized codons 14–25
(C-terminal part of helix a1 and the following loop)
and 93–102 (helix a6 and the b-turns N-terminal and
C-terminal ... a4 and 3900 out of the helix a6 pool and
obtained a total of 15 candidates with the desired
properties. These were confirmed by in vivo repression
and induction deter...
Tài liệu Báo cáo khoa học: "Japanese Dependency Parsing Using Co-occurrence Information and a Combination of Case Elements" pdf
... possible modifyees of “keisatsu-de” are “arui-
teiru” and “hogo-shita”. Taking into account in-
formation about the co-occurrence of “keisatsu-
de” and “arui-teiru” and of “keisatsu-de” and
“hogo-shita” ... probability
of the case element set (bunsetsu set) and the co-
occurrence probability of the particle set, and we
select the
ˆ
T that maximizes the probability.
Some...
Báo cáo khoa học: A new approach for distinguishing cathepsin E and D activity in antigen-processing organelles pdf
... is due to
CatD, and the decrease in activity can be assigned to CatE. The activity of
CatE and CatD in cytosolic, endosomal and lysosomal fractions of B cells,
dendritic cells and human keratinocytes ... on CatD activity (Fig. 4B). This approach for
depleting proteinase activity from complex biological
samples is flexible and can be used for other proteinases
as well.
Ac...
Báo cáo khóa học: Surface nucleolin participates in both the binding and endocytosis of lactoferrin in target cells potx
... relevant to this binding. Some of these
Fig. 10. Prediction of nucleolin -binding sites in human lactoferrin (hLf).
Sequences of the N2 and C2 domains of hLf, bovine lactoferrin (bLf)
and human transferrin ... Properties of the iron -binding site of the N-terminal lobe of
human and bovine lactotransferrins. Importance of the glycan
moiety and of the non-covalent...
Báo cáo khoa học: Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1⁄TSC2 in C2C12 myotubes pptx
... Distributions of TSC1 and TSC2 proteins in the membrane fraction and the cytosolic fraction. Alterations in the
relative amounts of both TSC1 and TSC2 proteins were quantified as a percentage of control ... a
small G protein. The GTP-bound active form of Rheb
strongly stimulates mTOR and its downstream targets,
such as the ribosomal S6 kinase 1 (S6K1) and the
eukaryotic in...
Báo cáo khoa học: "A GENERATIVE GRAMMAR APPROACH FOR THE MORPHOLOGIC AND MORPHOSYNTACTIC ANALYSIS OF ITALIAN" ppt
...
classes of endings: andare
(to go),
for example, admits two
different stems, vad (go) and and
(went);
so there exist two
subclasses of endings named respectively
dvl andare
and
dr2 andare. ... prep.simple 2
andare vad dv 1 _andare v.intran.simple 1
andare and I dv2. andar© v.intran.simple I
The other
sets
of data are contained in the Prolog workspace and
are struct...
Báo cáo khoa học: A single intersubunit salt bridge affects oligomerization and catalytic activity in a bacterial quinone reductase pptx
... of
reduction of the FMN cofactor was very small,
amounting to 0.6% and 3% of the wild-type rate for
the D137L and K109L ⁄ D137L protein variants,
respectively. The rate of reduction for the other two
protein ... with
binding of NADPH and ⁄ or delivery of a hydride to
the flavin cofacor and hence K109 plays a dual role by
supporting tetramer assembly through its intera...
Báo cáo khoa học: Tryptophan 243 affects interprotein contacts, cofactor binding and stability in D-amino acid oxidase from Rhodotorula gracilis ppt
... the
exposure of hydrophobic regions during the urea-
induced unfolding of W243 mutants compared with
the wild-type DAAO.
Kinetics of reconstitution of apoprotein with FAD
Because of the weaker binding of ... FAD cofactor to
the apoprotein of the W243 mutants, we studied the
kinetics of reconstitution of the apoprotein–FAD com-
plexes under pseudo-first-order conditions (10-...