Báo cáo khoa học: Aberrant interchain disulfide bridge of tissue-nonspecific alkaline phosphatase with an Arg433 fi Cys substitution associated with severe hypophosphatasia pdf
Báo cáo khoa học: Aberrant interchain disulfide bridge of tissue-nonspecific alkaline phosphatase with an Arg433 fi Cys substitution associated with severe hypophosphatasia pdf
... Journal compilation ª 2006 FEBS
Aberrant interchain disulfide bridge of tissue-nonspecific
alkaline phosphatase with an Arg433
fi
Cys substitution
associated with severe hypophosphatasia
Makiko Nasu
1
, ... tissue-non-specific alkaline phosphatase
with an Arg
54
fi Cys substitution and a counterpart
with an Asp
277
fi Ala substitution...
Tài liệu Báo cáo khoa học: Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family docx
... model of the
PDGF-C growth factor domain indicates the disulfide
bridges in PDGF-C to consist of Cys2 50 and 294,
Cys2 80 and 335, and Cys2 87 and 337, and the inter-
monomeric bonds to consist of Cys2 74 ... carcinoma, with enlarged liver having multilocular
pseudocysts without epithelial lining and showing
increased angiogenesis.
Both PDGF-A and -B are expressed in animal mod-...
Báo cáo khoa học: Comparing the substrate specificities of cytochrome c biogenesis Systems I and II docx
... the CXXAH variant of
P. denitrificans cytochrome c
550
is unstable and cannot
be made, the two single-cysteine-containing (and
AXXAH) variants of H. thermophilus cytochrome c
552
can form stably ... which
contribute to the handling of heme and
ligation of heme to the apocytochrome, and
those involved in the provision of reductant
to the apocytochrome in order to reduce a
potential d...
Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf
... variation of pH in the range
between 6.3 and 7.7, of ionic strength between 25 and
100 mm NaCl and of temperature between 278 and
313 K did not lead to any detectable change in the
populations of the ... Ter-Avanesyan
MD & Peltz SW (1998) The surveillance complex inter-
acts with the translation release factors to enhance
termination and degrade aberrant mRNAs. Genes Dev
12, 1...
Báo cáo khoa học: Molecular cloning, expression and characterization of protein disulfide isomerase from Conus marmoreus pdf
... sequence homology
with protein disulfide isomerases from other species, and 70% homology
with human protein disulfide isomerase. Enzymatic analyses of recombi-
nant C. marmoreus protein disulfide isomerase ... similarities with human protein disulfide isomerase. Using
conotoxins tx3a and sTx3.1 as substrate, we analyzed the oxidase and
isomerase activities of the C. marmoreus pr...
Báo cáo khoa học: Bacitracin inhibits the reductive activity of protein disulfide isomerase by disulfide bond formation with free cysteines in the substrate-binding domain pptx
... react with cysteines on PDI to form a
disulfide bond. Using MALDI-TOF ⁄ TOF MS analy-
sis, we were able to show that disulfide bond forma-
tion occurs between an open thiol form of bacitracin
and Cys3 14 ... coimmuno-
Fig. 5. Disulfide bond formation between bacitracin and Cys3 45 on PDI. (A) Scheme of thiol formation of the thiazoline ring of bacitracin A
with subsequent f...
Báo cáo khóa học: O-acetylation and de-O-acetylation of sialic acids in human colorectal carcinoma docx
... O-acetylation
phenotype of human colonic mucosa. J. Pathol. 174, 169–
174.
35. Jass, J.R., Allison, L.J. & Edgar, S.G. (1995) Distribution of sia-
losyl Tn and Tn antigens within normal and malignant colorectal
epithelium. ... can also undergo further modifications at any one of
four hydroxyl groups, located at C-4, -7, -8 and -9. One such
modification, the formation of O-acetyl est...