... Ozawa Y, Nakamura T, Kamata N, Yasujima D,Urushiyama A, Yamakura F, Ohmori D & Imai T(2005) Thermococcus profundus 2-ketoisovalerateferredoxin oxidoreductase, a key enzyme in the archaealenergy-producing ... donorsfor this key reaction [8].POR is distributed among archaea, bacteria andanaerobic protozoa, and is a member of the 2-oxoacidoxidoreductase (OR) family, which catalyzes the oxida-tive decarboxylation ... catalytic mechanism for the reductive carboxylation of acetyl-CoA catalyzed by POR. The HE-TPP radical is illustrated on the basis of the model proposed by Barletta et al. [57] with the unpaired...