Báo cáo khoa học: Cellular response to unfolded proteins in the endoplasmic reticulum of plants pptx

... aids, the assembly of other proteins, but is not part of the final assembly. Later, the focus of chaperone research shifted to the role in the folding of single protein chains and in protecting the ... proteins to be released and passed on to their final destination; misfolded proteins are retro- translocated to the cytosol for disposal. In contrast, mos...

Ngày tải lên: 07/03/2014, 06:20

... stability for crystallins is essential in maintaining lens transparency [4]. Determining the mechanism of folding and assembly of these proteins is important for understanding how they can form stable ... concentrations. The d 2 -crystallin in lens was recruited during evolution from argininosuccinate lyase, an enzyme involved in arginine biosynthesis derived from the urea c...

Ngày tải lên: 08/03/2014, 08:20

... one of the major causes of transitory diarrhea in the developing world. Toxin bind- ing to its receptor, guanylyl cyclase C (GC-C), results in receptor activation and the production of high intracellular levels ... a reappearance of the 145 kDa form on the cell surface, fol- lowing processing of the endoplasmic reticulum- associated pool of the 130 kDa form....

Ngày tải lên: 08/03/2014, 08:20

... sensitive to proteasome-induced apoptosis [16]. Although the treatment of cells with this compound causes marked increases in a large number of cellular proteins, including cyclin-dependent protein kinase ... used to investigate whether ALLN induced proteasome inhibition in canine chondrocytes. In the absence of ALLN, smears of ubiquitinated proteins were not observ...

Ngày tải lên: 18/02/2014, 14:20

... to War1p were raised in rabbits against a GST-War1p fusion protein containing 294 amino acids of the C-terminal part of War1p (amino acids 650– 944) fused in- frame to the C-terminus of GST. The ... expression of the C-terminal 294 amino acids of WAR1 fused in- frame to the C-terminus of GST. Escherichia coli strain DH5a harboring pCG1950 was grown on 37 °Ctoan...

Ngày tải lên: 19/02/2014, 00:20

... disallowed, then the complexity of the BU-LC parser with respect to the length of the input string is O(np+l), where p is the maximum number of daughters in a rule (Carroll, 1993). The inclusion of ... extract- ing a single analysis from the forest is worse than linear) 5. If one of the features of the ANLT grammar formalism, the kleene operator (al...

Ngày tải lên: 20/02/2014, 21:20

... found a set of DIDO1 homologues in the context of DNA binding and chromatin regulation. These homologues include members of the CpG binding protein (CGBP) family of proteins that bind DNA at unmethylated ... all appear to have a role in DNA regulation, in the context of chromatin stability, and to form part of higher complexes linked to active chromatin. The...

Ngày tải lên: 07/03/2014, 21:20

... higher organisms, this involves storing energy as fat during periods of an abundant food supply to hedge against periods of food shortage. Today, humans have pushed storage too far, to the point of widespread ... expenditure. Thus, insulin, leptin and ghrelin, as well as other hormones ⁄ cytokines, interact with their cognate receptors on neurons within the CNS that project to...

Ngày tải lên: 14/02/2014, 22:20

... expressions of the target language, although, of course, the individual grammars may be com- plicated because of the attuning. • Principle of Interllnguality: There is an intermediate language into ... transformation of the class yields a smaller S-tree according to this measure. The definition of M-GENERATOR is symmetric to the definition of M-PARSER• (There...

Ngày tải lên: 22/02/2014, 10:20

... mutant proteins results in increased mis- folding of normal proteins and further enhancement of co-aggregation. In this state, the degradation of mis- folded proteins is diminished by their insolubility, ... interact with other proteins. The improvement of microscopic techniques will promote the understanding of the dynamics and toxicity of mis- folded proteins...

Ngày tải lên: 06/03/2014, 09:22