Báo cáo khoa học: Biosynthesis of isoprenoids – studies on the mechanism of 2C-methyl-D-erythritol-4-phosphate synthase pdf
Báo cáo khoa học: Biosynthesis of isoprenoids – studies on the mechanism of 2C-methyl-D-erythritol-4-phosphate synthase pdf
... above, these initial conditions wererapidly conducive to steady conditions where 1 and 3were present in very similar concentrations, and the rates of the forward reaction (conversion of 1 to ... 4-phosphate[28]. The reductive reaction step has been shown toinvolve the transfer of a hydride ion from the pro-Sposition at C-4 of NADPH to the RE position of C-1 of reaction intermediate ... beyond the natural abundance level for the signals of C-3 and C-4 of a hypothetical product 1c. The hypothetical posi-tions of the 13C13C coupling satellites expected in the spectrum of 1c...
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Báo cáo khoa học: Structural and serological studies on a new 4-deoxy-D-arabino-hexosecontaining O-specific polysaccharide from the lipopolysaccharide of Citrobacter braakii PCM 1531 (serogroup O6) pptx
... using the authentic sample from the OPS of Citrobacter PCM 1487 [12] and PCM 1525 [13]. The absoluteLconfiguration of Rha andDconfiguration of Fuc and ara4dHex were determined by GLC-MS of the acetylated ... configurations of the monosaccharideswere established by GLC-MS of the acetylated (S)-2-octylglycosides [19].Methylation of the OPS was performed according to the method of Gunnarsson [20]. ... and monosaccharides were converted conventionallyinto alditol acetates [15] and analysed by GLC-MS. The content of ara4dHex was estimated by using the Cynkin–Ashwell method [16], the content of...
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Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc
... correlation of sucrose synthesisand degradation with the process of cold acclimation.We conclude that acclimation to low temperature rep-resents a dynamic process, the investigation of whichtherefore ... cAðtÞIn this reaction kinetic, the reaction rate rAfiB(t) depends on the substrate concentration cA(t) and the rate constant k. The model code and a detailed description of the modelstructure ... 1). The rate of net starch synthesis (rCO2!Starch)was deter-mined by interpolation of measured starch contents(unit: C6) and calculation of the first derivative of thisfunction. The flux...
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Tài liệu Báo cáo khoa học: Structural and functional studies on a mesophilic stationary phase survival protein (Sur E) from Salmonella typhimurium ppt
... structure of the C2-SurE to a resolution of 2.7 A˚. In both crystal forms the electron densityaccounted for the majority of the residues. There wereno disordered regions in the map. The quality of refinement ... formed by residues 3 4–5 0 under-goes conformational change from a ‘closed’ to an‘open’ form. The shift in the position of the loop awayfrom the metal ion leads to the formation of two inter-protomer ... corre-spond to that of the substrate mononucleoside phos-phate. The interactions of phosphorus with the metalion in C2-SurE may help to polarize the phosphate bondfor nucleophilic attack. The...
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
... structure-activity studies. The highselectivity of the a-conotoxins, together with the possibility of obtaining detailed information on their three dimen-sional structures and the relative ease of synthesis, ... differentsystems is therefore essential to prove the utility of the oocyte system and the validity of correlations based on the characterization of oocyte-expressed subunit combina-tions. Nevertheless, the ... ganglion [63] preparations, itshowed potent and selective inhibition of nAChR subpop-ulations. Among the a-conotoxins, MII has found the widest application in the characterization of a range of native...
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Tài liệu Báo cáo khoa học: Temperature and phosphate effects on allosteric phenomena of phosphofructokinase from a hibernating ground squirrel (Spermophilus lateralis) pptx
... are the result of one trialbut are representative of n ¼ 4 determinations from separate pre-parations of enzyme.Table 3. The effect of inorganic phosphate concentration on Mg.ATP kinetics of ... as the data set was typical of noncompetitive inhibition.Braxton et al. [17] previously defined the effect of anallosteric ligand on Vmaxvia the use of Arrhenius plotsthat graph the ratio of ... inhibition of PFK may not bephysiologically relevant [14]. Temperature-dependentmechanisms of enzyme control may contribute to the regulation of PFK activity as the body temperature of hibernators...
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Tài liệu Báo cáo khoa học: Local stability identification and the role of a key aromatic amino acid residue in staphylococcal nuclease refolding pdf
... association constant of SNase( 1–1 26)bound to pdTp in the presence of Ca2+is approxi-mately threefold lower than that of the wild-type pro-tein. Therefore, some or all of the residues in the 12 7– 149 ... secondarystructure only random coil. We can therefore postulatethat, when the segment beyond W140 was removed, the secondary structure of the protein disintegrated. Using the peak at 222 nm of ... maintenance of the nativeconformation of the protein. In addition, Griko andcoworkers [19], studying SNase( 1–1 36), showed thatthis fragment (residues 1–1 36) has no secondary struc-ture but retains the...
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Báo cáo khoa học: Concepts and tools to exploit the potential of bacterial inclusion bodies in protein science and biotechnology pdf
... chemical chaperones and modu-lation of the expression conditions to reduce the rate of protein biosynthesis [9,3 5–3 7], whereas in the secondmajor efforts are devoted to optimizing the refoldingprocess ... concerns aggregation propensity.Reports on the upregulation of the quality control sys-tem upon the accumulation of misfolded proteins in the cytoplasm suggest that this mechanism shares simi-lar ... overlapping mechanisms to protect theirproteins from aggregation. However, several reasons can cause the failure of such defences, among them mutations, stress conditions and high rates of protein synthesis,...
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Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc
... cell-cycle regulation The mode of action of RMI1 in the regulation of energy homeostasis might be based on the regulation of adipocyte hyperplasia. Studies have shown that siRNAknockdown of RMI1 resulted ... 567roles in the control of energy metabolism, leading tobody weight reduction. Further investigations to clarify the each contribution of adipocyte and central effects on the regulation of energy homeostasis ... proliferation. In addition, E2F8has been reported to reduce rather than induce cell pro-liferation [26,27]. Given the disparity in findings, eluci-dation of E2F8’s functions and contribution to the regulation...
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Báo cáo khoa học: Neural retina leucine-zipper regulates the expression of Ppp2r5c, the regulatory subunit of protein phosphatase 2A, in photoreceptor development pdf
... 505 1–5 060 ª 2010 The Authors Journal compilation ª 2010 FEBS 5051precise molecular mechanisms underlying the transcrip-tional control of PP2A genes and the effects of diversecombinations of ... site. Furthermore, the putative pro-moter region of the Ppp2r5c gene contained bindingsites for MZF1, CREB, GATA1, Hsf1 ⁄ 2 and CdxA.ABFig. 1. A conserved region of the Ppp2r5cpromoter contains ... P14 in the mouse retina(Fig. 4C), as well as the induction of Ppp2r5c tran-scripts that corresponded to the transcription factorassociation (Fig. 4E). However, prior to the associa-tion of Nrl...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Nguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Trách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMMÔN TRUYỀN THÔNG MARKETING TÍCH HỢP