Báo cáo khoa học: Betaine protects urea-induced denaturation of myosin subfragment-1 pptx

... Betaine protects urea-induced denaturation of myosin subfragment-1 Susana Ortiz-Costa 1,2 , Martha M. Sorenson 2 and Mauro ... methylamines. With the aim of comprehending the effects of urea on the catalytic (globu- lar) portion of myosin, this study examines the effects of urea and the countereffects of betaine on the catalytic ... presence of the urea and betai...

Ngày tải lên: 16/03/2014, 06:20

... lem of translation by projecting from the f-structure of a sentence of a given source language an addi- tional f-structure of its translation into some target language. Within the domain of ... resp. argument of the interpretation of their unifi- cation. This is then assigned the value-type of the functor. Figure 8 shows how the semantic represen- tation of one readi...

Ngày tải lên: 22/02/2014, 10:20

... selection of co-occurrences is part of the lexical pro- cess, in other words, if there are reasons not to choose a co- occurrence because of the presence of modifiers or because of stylistics ... context of a pupil rather than any other element belonging to the paradig- matic family of teacher such as professor, instructor. Formally, there is no difference between th...

Ngày tải lên: 08/03/2014, 06:20

... existence of statistically significant correlations between pairs of events and relation words. The left column of Tab. 1 shows the number of triples obtained from PukWaC sub- corpora of different ... in terms of theoretically-defined dis- course relations ?). 3.1 Significance and Reproducibility Significance tests are part of the pruning stage of the algorithm. Therefore, the num...

Ngày tải lên: 16/03/2014, 20:20

... treatment Appearance of phosphatidylserine (PS) in the outer leaflet of the phospholipid bilayer without disrupted integrity of the membrane is one of the earliest char- acteristics of apoptotic cells. ... through the prevention of activation of apoptotic markers at an early stage, including PS exposure to the outer membrane – one of the first detectable signs of apopto- sis [...

Ngày tải lên: 18/02/2014, 18:20

... determined by the rate of association. It should be noted that quanti- tative analysis of the more rapid phase of association requires measurement of the binding on time scales of minutes, a time ... presence of unlabeled PCSK9 (Fig. 4A). In the presence of a high concentration of unlabeled wild-type PCSK9, the half- time of the rapid phase was reduced from 19 to 16 min and...

Ngày tải lên: 14/02/2014, 14:20

... analysis of purified PhyH, PhyH-DI and PhyH-DII. Lane M, molecular weight markers; lane 1, culture supernatant of PhyH; lane 2, culture supernatant of PhyH-DII; lane 3, culture supernatant of PhyH-DI; ... Environmental factors that affect the catalytic activities of PhyH and PhyH-DII. (A) Effect of 0–5.0 mM Ca 2+ at 37 °C. (B) Effect of pH at 37 °C. (C) Effect of temperature at...

Ngày tải lên: 14/02/2014, 15:20

... University of Bath, UK 2 Department of Biochemistry, University of Wisconsin–Madison, USA 3 Department of Chemistry, University of Wisconsin–Madison, USA Introduction Upon catalyzing the cleavage of ... regarding a new class of surrogates for the phosphoryl group. Results and Discussion Sulfonimides as inhibitors of RNase A We began by determining the ability of three backbo...

Ngày tải lên: 14/02/2014, 22:20

... transfer of phosphate esterified in the 5¢ position of 6-hydroxypu- rine monophosphate nucleosides [1]. The transfer of phosphate can lead to phosphorylation of inosine, guanosine and a number of their ... disappearance of the heavier inactive peak. Furthermore, FPLC analysis of the recombinant wild-type cN-II showed the presence of the tetrameric active form irrespective of...

Ngày tải lên: 15/02/2014, 01:20

... K m ) of PRTFDC1 towards hypoxanthine and guanine was only 0.26% and 0.09%, respectively, of that of HPRT. This low activity could be explained by the fact that PRTFDC1 has a Gly in the position of the ... metabolic consequences of having HPRT deficiency are an overproduction of uric acid and elevated levels of PRPP [3]. Patients hav- ing mutations resulting in partial HPRT defici...

Ngày tải lên: 15/02/2014, 01:20