Báo cáo khoa học: Molecular basis for speciﬁcities of reacti

Báo cáo khoa học: Comparing the substrate speciﬁcities of cytochrome c biogenesis Systems I and II docx

... addition of a few grains of disodium dithionite. The Soret and a-band absorbance maxima are at 415 and 550 nm, respectively, for wild-type cytochrome c 550 , and at around 419 and 555 nm for the ... but for their encoded operons), permit a reﬁnement of the conclusion of the former work. We found here low but detectable levels of the holo-forms of AXXCH variants of...

Ngày tải lên : 06/03/2014, 09:22

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Báo cáo khoa học: Molecular basis for speciﬁcities of reactivating factors for adenosylcobalamin-dependent diol and glycerol dehydratases pptx

... 2007 FEBS Molecular basis for specificities of reactivating factors for adenosylcobalamin-dependent diol and glycerol dehydratases Hideki Kajiura 1 , Koichi Mori 1 , Naoki Shibata 2 and Tetsuo ... specific for glycerol dehydratase, the cognate dehydratase. Specificities of reactivating factors in the complex formation with dehydratases DDR and GDR form...

Ngày tải lên : 16/03/2014, 05:20

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Báo cáo khoa học: Probing the substrate speciﬁcities of matriptase, matriptase-2, hepsin and DESC1 with internally quenched ﬂuorescent peptides potx

... consisting of amino acids 45–417) and 30 kDa (autocatalytically processed form consisting of amino acids 163–417). The absence of higher molecular mass forms of DESC1 and matriptase-2 suggests that, under ... presence of a pair of basic residues (substrate 13) led to a ﬁvefold increase in k cat ⁄ K m value. Overall, the permissiveness of DESC1 for P3, P2 and P1¢ was...

Ngày tải lên : 23/03/2014, 04:21

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Báo cáo khoa học: Molecular basis of the unusual catalytic preference for GDP/GTP in Entamoeba histolytica 3-phosphoglycerate kinase doc

... the yeast and amebal PGKs. 3D predicted model of EhPGK Predicted 3D structures of the EhPGK were obtained by means of modeller software (see Fig. S1 for details on these models) and molecular ... with GDP ⁄ GTP and lower afﬁnities for the adenine nucleotides. To elucidate the molecular basis of the Entamoeba histolytica phosphoglycerate kinase selectivity for GDP ⁄ G...

Ngày tải lên : 16/03/2014, 01:20

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Báo cáo khoa học: Molecular basis for substrate recognition and drug ˚ resistance from 1.1 to 1.6 A resolution crystal structures of HIV-1 protease mutants with substrate analogs pptx

... W. Harrison 2,4 and Irene T. Weber 1,2 1 Department of Chemistry, Molecular Basis of Disease, Georgia State University, Atlanta, GA, USA 2 Department of Biology, Molecular Basis of Disease, Georgia ... Atlanta, GA, USA 3 Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Hungary 4 Department of Computer Science, Molecu...

Ngày tải lên : 30/03/2014, 20:20

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Tài liệu Báo cáo khoa học: Molecular basis of glyphosate resistance – different approaches through protein engineering doc

... some of the key ﬁndings that have led to our current understanding of the molecular mode of action of glyphosate and the molecular basis for glyphosate resistance. Structure and function of ... advantage of combining tools for enzyme optimiza- tion. With the increasing demand for food and biofuel, all available technologies should be explored to iden- tify fe...

Ngày tải lên : 14/02/2014, 14:20

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Báo cáo khoa học: Molecular basis of perinatal hypophosphatasia with tissue-nonspeciﬁc alkaline phosphatase bearing a conservative replacement of valine by alanine at position 406 Structural importance of the crown domain potx

... 1023–1034. N. Numa et al. Molecular basis of perinatal form of hypophosphatasia FEBS Journal 275 (2008) 2727–2737 ª 2008 The Authors Journal compilation ª 2008 FEBS 2737 Molecular basis of perinatal hypophosphatasia ... Left lane: 14 C-methylated protein markers of 200, 97.5, 66, 46 and 30 kDa, from the top of the gel. N. Numa et al. Molecular basis of perinatal form...

Ngày tải lên : 07/03/2014, 05:20

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Báo cáo khoa học: Molecular basis of toxicity of Clostridium perfringens epsilon toxin ppt

... target cell speciﬁcities of aerolysin and e-toxin, and the different function of LSL, is the result of the different structures and properties of these domains. The second and third domains of e-toxin ... is a b-sandwich, containing a ﬁve-stranded sheet and a b-hairpin (both of which are anti-parallel). The third domain is a b-sandwich composed of one four- stranded...

Ngày tải lên : 14/03/2014, 22:20

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Báo cáo khoa học: Molecular basis of cytokine signalling – theme and variations docx

... structure of the extracellular ligand-binding domain of a number of these receptor complexes has now been elucidated, providing the molecular basis for understanding the func- tional relevance of mechanistic ... receptor of the ligand, whereas the main core structure binds into the epitope for the type II receptor of the BMP ligand. Therefore, the binding of the receptor...

Ngày tải lên : 15/03/2014, 09:20

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Báo cáo khoa học: Molecular basis of cerebral neurodegeneration in prion diseases pdf

... targeting and trafﬁcking of PrP. The term ‘toxicity’ is used by us here for induction of neurodegeneration, and PrP Sc is used synonymously for the pathological form of PrP. Toxicity of transmembrane ... the cellular function of the normal cellular isoform of prion protein is not exactly known, the impact of gain of toxic function or loss of function, or a combin...

Ngày tải lên : 30/03/2014, 09:20

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