Báo cáo khoa học: The effects of a-secretase ADAM10 on the proteolysis of neuregulin-1 pot

Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx

Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx

... other methods, because it enables one to develop a broader perspective of the questions within an analysis of the hypothesis in the con- text of a characterization of the "how" of ... result of acti- vation of a pragmatic representation of a disambiguated word meaning. It is the in interaction of the results of these asynchronous processes that...

Ngày tải lên: 21/02/2014, 20:20

5 610 0
Tài liệu Báo cáo khoa học: "Language Resources Factory: case study on the acquisition of Translation Memories" potx

Tài liệu Báo cáo khoa học: "Language Resources Factory: case study on the acquisition of Translation Memories" potx

... Proceedings of the 13th Conference of the European Chapter of the Association for Computational Linguistics, pages 1–5, Avignon, France, April 23 - 27 2012. c 2012 Association for Computational Linguistics Language ... to continue processing the rest of the input data if the workflow is robust (i.e. makes use of retry and parallelisation) and the error is confined to a...

Ngày tải lên: 22/02/2014, 03:20

5 532 0
Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx

Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx

... and E97 of the second subunit. The backbone NH group of R98 forms a hydrogen bond with the backbone CO of F102. Fur- thermore, the orientation of the side chain of the two residues brings the guanidinium ... interaction (Fig. 9B) [49]. The above discussion rationalizes the observed effects of the Y74W mutation in PfTIM on the stability of the dimeric...

Ngày tải lên: 18/02/2014, 11:20

15 635 0
Tài liệu Báo cáo khoa học: Functional effects of deleting the coiled-coil motif in Escherichia coli elongation factor Ts pptx

Tài liệu Báo cáo khoa học: Functional effects of deleting the coiled-coil motif in Escherichia coli elongation factor Ts pptx

... show the positions of the protruding coiled-coil motif (residues 187–226) and the C-terminal module. The terminal positions of the deletion of the coiled-coil motif and the insertion of the linker ... for the analysis to ensure that the concentrations of ligands were maintained at a constant level during migration of the elongation factors, thereby favouring...

Ngày tải lên: 21/02/2014, 00:20

12 502 0
Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx

Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx

... posi- tioned in the connecting loops. Approximately one- third of all mutations in the BTK gene are missense and some of these reduce the stability of the protein. This is exemplified by mutations ... substitution of the corresponding R25 in the pleckstrin homology (PH) domain also results in loss of function [16,17], thereby demonstrating related functions among selected...

Ngày tải lên: 14/02/2014, 18:20

10 927 0
Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx

Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx

... other enzymes in neurons. Alternatively, the inhibition of neuronal long-chain fatty acid oxidation could contrib- ute to body weight control. The roles of long-chain fatty acyl-CoAs and long-chain fatty ... effects on malonyl-CoA concentration in the short-term [27]. Aside from the public health aspects of the affects of fructose on food intake, these findings lend fur...

Ngày tải lên: 14/02/2014, 22:20

7 679 0
Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc

Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc

... modu- lation of Ca 2+ oscillations by increasing agonist con- centration [44]. The dependences of the period of oscillations on the RPTP and Csk concentrations almost mirror each other, although there ... that mirror stimulation or changes in the external condi- tions. We consider the time scale on which the total Src concentration (S tot ) is conserved. Neglecting the...

Ngày tải lên: 18/02/2014, 11:20

17 513 0
Tài liệu Báo cáo khoa học: A facile method for expression and purification of the Alzheimer’s disease-associated amyloid b-peptide pdf

Tài liệu Báo cáo khoa học: A facile method for expression and purification of the Alzheimer’s disease-associated amyloid b-peptide pdf

... prevent degradation. A common drawback of such approaches is the cost of the affinity resins used to isolate the fusion protein and the proteases required to liberate the protein of interest from the fusion ... using the devices and loss of peptide on the column resin. The only detriment of the peptides produced here is the fact that they contain an exo- genou...

Ngày tải lên: 18/02/2014, 13:20

16 691 0
Tài liệu Báo cáo khoa học: Antimicrobial effects of H4-(86–100), histogranin and related compounds – possible involvement of DNA gyrase ppt

Tài liệu Báo cáo khoa học: Antimicrobial effects of H4-(86–100), histogranin and related compounds – possible involvement of DNA gyrase ppt

... evaluate the rapidity of action of his- tone H4 peptides and compare it with that of the quinolone antibiotic ciprofloxacin, the LD 50 values of Fig. 2. ATP potentiation of the bactericidal activity of ... to the mucous surface of epithelial cells to prevent the entry of bacteria into the epithelial layer and their invasion into the lower parts of the gastro...

Ngày tải lên: 18/02/2014, 14:20

12 756 0
Tài liệu Báo cáo khoa học: Verprolin function in endocytosis and actin organization Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain doc

Tài liệu Báo cáo khoa học: Verprolin function in endocytosis and actin organization Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain doc

... level of the untagged pro- teins, but we expect that the relative expression level of the tagged proteins is indicative of that of the equival- ent untagged proteins. To assess the function of these ... polarization is further evidence that the functions of Vrp1p in endocytosis, cytokinesis, and growth at elevated temperature, on the one hand, and in cortical actin...

Ngày tải lên: 18/02/2014, 16:20

23 680 0
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