Báo cáo khoa học: Vanadium-induced apoptosis of HaCaT cells is mediated by c-fos and involves nuclear accumulation of clusterin pptx

... 2009 FEBS 3799 Vanadium-induced apoptosis of HaCaT cells is mediated by c-fos and involves nuclear accumulation of clusterin Soultana Markopoulou 1, *, Evangelos Kontargiris 1, *, Christina Batsi 1, *, ... vanadium- induced apoptosis of HaCaT cells was mediated by c-fos and involved induction of total Bax and upregulation and accumulation...

Ngày tải lên: 16/03/2014, 02:20

... the Experimental procedures. This model is strongly sup- ported by previous research on the mechanism of RNA recognition for RRM proteins [6,39,40] and by the structure of existing KH domains bound ... set of protein–RNA decoys for the RNA, DNA and reduced atom distance potentials in decoy discrim- ination. Table S5. Comparison of the performance of the potential with diff...

Ngày tải lên: 18/02/2014, 16:20

... DABY and PSAO (r ¼ 17) [7]. From this point of view, plant CAOs are more resistant to the inactivation by DAPY than by DABY. Binding of DAPY at the active site of GPAO is dependent on both pH and ionic ... recorded by courtesy of Dr Martin Modriansky´ from the Institute of Medical Chemistry and Biochemistry, Faculty of Medicin e, Palacky´ University. Dr Ivo Fre ´ bor...

Ngày tải lên: 19/02/2014, 16:20

... cell development and differentiation, nuclear anchoring and migration, and apoptosis (reviewed in [1,2]). Mutations in several of the integral membrane proteins of the inner nuclear membrane ... hyperostosis is accompanied by abnormalities of adjacent soft tissues, such as joint contractures, sclerodermatous skin lesions, muscle atrophy, hemangiomas and lymphoedema [17...

Ngày tải lên: 19/02/2014, 02:20

... undergo apoptosis (Fig. 1 and Table 1). This process is accompanied by aggresome formation in the vast majority of transfected cells and marked inhibition of proteasome function. In the case of anti-(Ras ... apoptosis in a high percentage of trans- fected cells and inhibit cell growth in different cell lines. This phenomenon is accompanied by the formation of a...

Ngày tải lên: 21/02/2014, 00:20

... Bcl-2 and Bcl-x L , resulting in tumor-specific sup- pression of apoptosis and enhancement of the malignance and therapy resistance of tumors [39–43]. The existence of a high background level of ... release of mitochondrial cyt-c in HepG2 cells Our previous publications were devoted to the study of AFP-induced apoptosis in whole cells and suggested that this mecha...

Ngày tải lên: 08/03/2014, 08:20

... control of gene expression. As each step of the RNA metabolism is tightly regulated, the regulation of mRNA export, stability and transla- tion rate is essential for the control of the expression of ... the nuclear fraction of ASF ⁄ SF2 is phosphorylated [31,32] and ASF ⁄ SF2 nuclear export is conditioned by a dephosphorylation process [ 33,34], we analyzed th e...

Ngày tải lên: 16/02/2014, 15:20

... Ban and his collaborators (ETH, Zurich) for supplying the plasmids with tRNA Sec synthetic genes. This work was supported by grants from the Ministry of Science and Technology of the Republic of ... kinetics of serylation and tRNA discrimination by the two SerRSs that coexist in methanogenic archaeon Methanosarcina barkeri [16] (D. Korencic, unpublished data). One of these...

Ngày tải lên: 19/02/2014, 12:20

... Tfu, Tfus02000308 of Thermobifida fusca.The Rv2228c of M. tuberculosis is identical to Mb2253c of Mycobacterium bovis. N. Ohtani et al. A fusion protein consisting of RNase H and APase FEBS Journal 272 (2005) ... examined here is a bifunctional enzyme con- sisting of an RNase H domain and an APase domain, and it is a novel style in the Type 1 RNase H family. Experimental...

Ngày tải lên: 19/02/2014, 18:20

... chunk–pair–distance model is computed from the list of chunks. This is done by traversing the chunks from left to right. For each chunk c i , a set is computed by considering all remaining chunks and ... distance to c i , i.e., (c i , c i+1 , dist i(i+1) ), (c i , c i+2 , dist i(i+2) ), etc. We do this for each chunk list computed for each web snippet. The distance dist ij of...

Ngày tải lên: 20/02/2014, 05:20