Báo cáo khoa học: ATP-binding domain of heat shock protein 70 is essential for its effects on the inhibition of the release of the second mitochondria-derived activator of caspase and apoptosis in C2C12 cells potx
Báo cáo khoa học: ATP-binding domain of heat shock protein 70 is essential for its effects on the inhibition of the release of the second mitochondria-derived activator of caspase and apoptosis in C2C12 cells potx
... respect to the role of HSP70 in the inhi- bition of the release of Smac and apoptosis. The role of the ATP-binding domain of HSP70 in the prevention of the release of Smac and apoptosis after exposure ... activation of caspases-9 and -3 and apoptosis. (A) The effects of HSP70 and its deletion mutant proteins on the acti- vati...
Ngày tải lên: 16/03/2014, 01:20
Báo cáo khoa học: Mammalian 105 kDa heat shock family proteins suppress hydrogen peroxide-induced apoptosis through a p38 MAPK-dependent mitochondrial pathway in HeLa cells potx
... apoptosis upstream of rather than by direct inhibition of caspase- 3 activation, as they do not suppress the activation of caspase- 3 mediated by heat shock. In mammalian cells, one of the main pathways ... staurosporine-induced apoptosis by inhibiting the translocation of Bax to mitochondria [19]. In contrast, Hsp105a has the opposite effects on apoptos...
Ngày tải lên: 16/03/2014, 06:20
Tài liệu Báo cáo khoa học: Nucleolin/C23 mediates the antiapoptotic effect of heat shock protein 70 during oxidative stress pptx
... apoptosis- inducing factor. Nat Cell Biol 3, 839–843. 24 Jiang B, Wang K, Xiao W, Wang H & Xiao X (2009) ATP-binding domain of heat shock protein 70 is essen- tial for its effects on the inhibition ... November 2009) doi:10.1111/j.1742-4658.2009.07510.x Although heat shock protein 70 (Hsp70) has been shown to markedly inhi- bit H 2 O 2 -induced apopto...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: "Cross-Domain Co-Extraction of Sentiment and Topic Lexicons" pdf
... scheme for domain- transfer problem in the context of sentiment analysis. In Pro- ceedings of the 16th ACM conference on Conference on information and knowledge management, pages 979–982, Lisbon, ... summarized in Algorithm 1, for expanding lexicons across do- mains. In each iteration, we employ a cross -domain classifier trained on the source domain lexicons...
Ngày tải lên: 19/02/2014, 19:20
Tài liệu Báo cáo khoa học: A novel coupled enzyme assay reveals an enzyme responsible for the deamination of a chemically unstable intermediate in the metabolic pathway of 4-amino-3-hydroxybenzoic acid inBordetellasp. strain 10d doc
... assay, the enzyme reaction product identified by GC-MS analysis, and the determination of released ammonia. The coupled enzyme assay revealed the mechanism of the deamination reaction and the subsequent ... n color. The enzyme s olution showed one main absorption peak at 266 nm and a broad absorption band in the visible region (Fig. 4). The excitation spectrum of...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: "Using Multiple Sources to Construct a Sentiment Sensitive Thesaurus for Cross-Domain Sentiment Classification" doc
... 2007) focuses on the challenge of training a classifier from one or more domains (source domains) and applying the trained classi- fier in a different domain (target domain) . A cross- domain sentiment ... shows the effect of combining multiple source domains to build a sentiment classifier for the electronics domain. We see that the kitchen do- main is the single...
Ngày tải lên: 20/02/2014, 04:20
Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt
... been demonstrated that the unfavourable interaction between the peptide backbone and the osmolytes leading to the preferential hydration of the protein domain is the driving force of protein stabiliza- tion ... (a) the main driving force for the folding is the unfavourable interaction between the osmolyte and the peptide back- bone, and (b) the to...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: A novel metallobridged bis(b-cyclodextrin)s fluorescent probe for the determination of glutathione doc
... experiments. In uence of the concentration of metallobridged bis(b-CD)s 2 The in uence of the concentration of 2 on fluorescence intensity is shown in Fig. 4. As can be seen, as the concentration of 2 increased, ... reaction was left to proceed for 10 min, and the fluorescence was then measured at room tem- perature. In uence of interference The in uence o...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Copper-containing nitrite reductase fromPseudomonas chlororaphis DSM 50135 Evidence for modulation of the rate of intramolecular electron transfer through nitrite binding to the type 2 copper center pot
... atom is then broken, yielding the product NO, whose release re-establishes the original coordination of the active center. HisB255 could be involved in the formation of additional hydrogen bonding, ... while the T2Cu is the catalytic center [7]. The study of this protein therefore entails the investigation of three redox processes: the reduction of T1Cu b...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: "Cross-Domain Dependency Parsing Using a Deep Linguistic Grammar" docx
... shorter in BROWN than that in WSJ. The common interpretation is that the test set is heterogeneous to the training set, hence in a different domain (in a loose sense). The typical cause of this is ... is that the model overfits the training domain. The concerns over random choice of training corpus leading to linguistically inadequate parsing systems increase...
Ngày tải lên: 08/03/2014, 00:20