Báo cáo khoa học: Stability and ﬁbril formation properties o

Báo cáo khoa học: Lysophosphatidylcholine modulates ﬁbril formation of amyloid beta peptide doc

... freezing the samples. Assessment of Ab fibril formation on the basis of ThT fluorescence The presence of b-sheet structures and the kinetics of fibril formation were monitored by means of ThT fluorescence spectroscopy. ... lg of synthetic Ab monomer was incu- bated in fibril formation buffer in the presence of 0.2 l gof sonicated Ab fibrils in a total vol...

Ngày tải lên : 06/03/2014, 01:20

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Báo cáo khoa học: Stability and ﬁbril formation properties of human and ﬁsh transthyretin, and of the Escherichia coli transthyretin-related protein potx

... ª 2009 FEBS 2011 Stability and ﬁbril formation properties of human and ﬁsh transthyretin, and of the Escherichia coli transthyretin-related protein Erik Lundberg 1 , Anders Olofsson 2 , Gunilla ... with the thermostability of its tetrameric and monomeric structures. Thermostability and protein structures We have analyzed the structures of hT...

Ngày tải lên : 16/03/2014, 01:20

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Báo cáo khoa học: GlnK effects complex formation between NifA and NifL in Klebsiella pneumoniae docx

... control both synthesis and activity of nitrogenase in response to o xygen and nitrogen availability, because of the high energy demands of nitrogen ﬁxation and the oxygen sensitivity of nitrogenase [1,2]. ... conditions. Protein synthesis of approximately equivalent amounts of all three proteins was induced from plasmid pRS209, which contains the operon malE-nifLA...

Ngày tải lên : 07/03/2014, 16:20

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Báo cáo khoa học: Soluble recombinant CD69 receptors optimized to have an exceptional physical and chemical stability display prolonged circulation and remain intact in the blood of mice doc

... after injection. Moreover, the exclusion of the protein in urine and faeces, and uptake by the liver, was relatively low. On the other hand, the least stable human CD69NS84 protein dis- played a rapid ... biochemical stability. Interest- ingly, the stability of the short proteins CD69NV82 and CD69NS84 is much lower using these criteria, both from the point...

Ngày tải lên : 16/03/2014, 04:20

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Báo cáo khoa học: "Veterinary decision making in relation to metritis - a qualitative approach to understand the background for variation and bias in veterinary medical records"

... at the herd level. They perceive the collection of the data in and of itself as the basis for taking relevant action at the farm. They may skip the process of systematic analysis of data and ... understanding with regard to decision levels Based on analysis of the veterinarians' perceptions of how they wished to use the metritis score in their practice...

Ngày tải lên : 25/10/2012, 10:45

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Tài liệu Báo cáo khoa học: Role for nectin-1 in herpes simplex virus 1 entry and spread in human retinal pigment epithelial cells docx

... in terms of its ability to enter the cells of the retina, the present study used retinal pigment epithelial (RPE) cells as a model to deter- mine the susceptibility and the mediators of HSV-1 entry ... nec- tins induce formation of ﬁlopodia and lamellipodia through the respective activation of Cdc42 and Rac small G proteins. J Biol Chem 277, 50749–50755. Suppor...

Ngày tải lên : 18/02/2014, 14:20

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Tài liệu Báo cáo khoa học: 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5¢-phosphate synthases of fungi and archaea docx

... synthase. The putative genes were of two types, either with the two-domain architecture of the RibG protein of Bacil- lus subtilis or the RibD protein of E. coli, respectively [18–20], or the single-domain ... catalysing the transfer of deuterium from the 4(R) position of NADPH to the 1¢ (S) position of the substrate. These results are in agreement with t...

Ngày tải lên : 18/02/2014, 18:20

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Tài liệu Báo cáo khoa học: DNA modiﬁcation with cisplatin affects sequence-speciﬁc DNA binding of p53 and p73 proteins in a target site-dependent manner pptx

... cisplatin and the ability of the particular p53 target site to accommodate the cisplatin IACs. The higher the probability of formation of the cisplatin IACs within the p53DBSs due to the occurrence of the ... weights of the p73 isoforms. To verify the speciﬁcity of the band shifts for DNA complexes with the proteins studied, we used the band supersh...

Ngày tải lên : 19/02/2014, 05:20

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Tài liệu Báo cáo khoa học:Symmetric fluoro-substituted diol-based HIV protease inhibitors Ortho-fluorinated and meta-fluorinated P1/P1¢-benzyloxy side groups significantly improve the antiviral activity and preserve binding efficacyy docx

... and retained the binding efficacy. The flexibility of the target molecule complicates the prediction of an effect caused by a modification on the inhibitor and necessitates structural analysis of ... 2004 Structure of the complexes The crystal structures of the six protease–inhibitor complexes have been solved and refined down to 1.8–2.3 A ˚ resolution with R cry...

Ngày tải lên : 19/02/2014, 16:20

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Tài liệu Báo cáo khoa học: Various secretory phospholipase A2 enzymes are expressed in rheumatoid arthritis and augment prostaglandin production in cultured synovial cells docx

... (Fig. 3Dc). These results, together with the results of RT-PCR and western blot (Fig. 1), implies that the expression of sPLA 2 -IIF in RA is rather lower than that of other sPLA 2 s and does not ... sPLA 2 to evaluate the expression and localization of six sPLA 2 s (IIA, IID, IIE, IIF, V and X) in human joints affected by RA. We further examined the possible contrib...

Ngày tải lên : 19/02/2014, 16:20

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