Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx

Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx

Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx

... cloning, expression and function in tumor progression and metastasis. Nat Med 5, 793–802. 23 Ilan N, Elkin M & Vlodavsky I (2006) Regulation, function and clinical significance of heparanase in ... al. New concepts for heparanase function FEBS Journal 277 (2010) 3890–3903 ª 2010 The Authors Journal compilation ª 2010 FEBS 3903 MINIREVIEW Proteoglycans in...
Ngày tải lên : 15/03/2014, 23:20
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Báo cáo khoa học: An a-proteobacterial type malate dehydrogenase may complement LDH function in Plasmodium falciparum Cloning and biochemical characterization of the enzyme potx

Báo cáo khoa học: An a-proteobacterial type malate dehydrogenase may complement LDH function in Plasmodium falciparum Cloning and biochemical characterization of the enzyme potx

... important amino acid residues lining these pockets. The active site amino acid residues involved in substrate b inding were con served in Pf MDH but the N-terminal glycine motif, which is involved in ... the enzyme and the inhibitors were preincubated f or 10 min before i niti- ating the reaction by addition of NADH. Bovine heart LDH (j/solid line); Pf LDH ( d/broken line); Pf MDH (h/...
Ngày tải lên : 16/03/2014, 18:20
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Tài liệu Báo cáo khoa học: "You’ve Got Answers: Towards Personalized Models for Predicting Success in Community Question Answering" doc

Tài liệu Báo cáo khoa học: "You’ve Got Answers: Towards Personalized Models for Predicting Success in Community Question Answering" doc

... model. 1 Introduction Community Question Answering (CQA) has re- cently become a viable method for seeking infor- mation online. As an alternative to using general- purpose web search engines, information ... We formalize this problem, and explore a variety of content, structure, and interaction features for this task using standard machine learning techniques. Our experimental evalua...
Ngày tải lên : 20/02/2014, 09:20
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Báo cáo khoa học: Molecular basis of the unusual catalytic preference for GDP/GTP in Entamoeba histolytica 3-phosphoglycerate kinase doc

Báo cáo khoa học: Molecular basis of the unusual catalytic preference for GDP/GTP in Entamoeba histolytica 3-phosphoglycerate kinase doc

... amino acid side chains. Amino acid residues interacting with the guanine moiety of GDP in EhPGK The amino acid residues known to interact with the adenine moiety in the ADP ⁄ ATP-binding site in ... green) and E. his- tolytica PGK predicted model with GDP (red) obtained using MOE software. (B) Close up of the purine ring binding site in the C-terminal domain. Lines indicate hydrogen...
Ngày tải lên : 16/03/2014, 01:20
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Báo cáo khoa học: "LIMITS OF A SENTENCE BASED PROCEDURAL APPROACH FOR ASPECT CHOICE IN GERMAN-RUSSIAN MT" potx

Báo cáo khoa học: "LIMITS OF A SENTENCE BASED PROCEDURAL APPROACH FOR ASPECT CHOICE IN GERMAN-RUSSIAN MT" potx

... Berlin ABSTRACT In this paper we discuss some problems arising in German-Russian Machine Translation with regard to tense and aspect. Since the formal category of aspect is missing in German ... German main clauses into Russian including the decision of appropriate aspect forms for simple and complex verbal groups. We distinguish five different types of criteria all of them...
Ngày tải lên : 01/04/2014, 00:20
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Báo cáo khoa học: "A Hierarchical Approach to Encoding Medical Concepts for Clinical Notes" docx

Báo cáo khoa học: "A Hierarchical Approach to Encoding Medical Concepts for Clinical Notes" docx

... with empty in- stance in its subtree were removed from the training and testing stage. When training a classifier for a node A in the tree, all the instances in the subtree rooted in the parent ... only source of training instances. For instance, code ‘786.0’ in Figure 2 uses all the 698 in- stances rooted in node ‘786’ as the full training data set. The 98 instances root...
Ngày tải lên : 31/03/2014, 00:20
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Báo cáo khoa học: "Multi-Class Composite N-gram Language Model for Spoken Language Processing Using Multiple Word Clusters" pptx

Báo cáo khoa học: "Multi-Class Composite N-gram Language Model for Spoken Language Processing Using Multiple Word Clusters" pptx

... Word Clustering for Multi-Class 2-grams For word clustering in class N-grams, POS in- formation is sometimes used. Though POS in- formation can be used for words that do not ap- pear in the corpus, ... clustering for 2-grams to 3-grams, the clustering target in the conditional part is extended to a word pair from the single word in 2-grams. Number of clustering targets in...
Ngày tải lên : 31/03/2014, 04:20
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Báo cáo khoa học: Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans ppt

Báo cáo khoa học: Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans ppt

... lumican-evoked signaling, including vinculin and focal adhesion kinase [82]. Lumican alters the relationship between actin filaments and b1 integrin, which in turn would affect focal adhe- sion formation, ... with the EGF-binding domain [32]. The structural constraints of the EGFR binding region support a stochiometry of 1 : 1 for the decorin pro- tein core and EGFR, suggesting that...
Ngày tải lên : 15/03/2014, 23:20
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Báo cáo khoa học: Proteoglycans in health and disease: the multiple roles of syndecan shedding ppt

Báo cáo khoa học: Proteoglycans in health and disease: the multiple roles of syndecan shedding ppt

... (2010) Proteoglycans in health and disease: new concepts arising for heparanase func- tion in tumour progression and metastasis. FEBS J 277, 3890–3903. 118 Purushothaman A, Chen L, Yang Y & Sanderson ... (GAIP)-interacting C-terminus ⁄ synectin and calc ium ⁄ calmodulin-associated serine kinase, since the C2 region contains a class II PSD-95 ⁄ Discs-large ⁄ Zonu...
Ngày tải lên : 15/03/2014, 23:20
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Tài liệu Báo cáo khoa học: DNA modification with cisplatin affects sequence-specific DNA binding of p53 and p73 proteins in a target site-dependent manner pptx

Tài liệu Báo cáo khoa học: DNA modification with cisplatin affects sequence-specific DNA binding of p53 and p73 proteins in a target site-dependent manner pptx

... weak p53 binding (about 4% for mdm2 and PGM1 and 10% for p21). Sensitivity of the sequence-specific p53 DNA binding to DNA cis-platination depends on the incidence of cisplatin-reactive motifs within ... target site, the intensity of the R 53 band resulting from p53 binding to unmodified DNA was taken as 1.0, and the intensities of bands correspond- ing to p53 binding to the same but...
Ngày tải lên : 19/02/2014, 05:20
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