Báo cáo khoa học: Pyruvate:ferredoxin oxidoreductase and bifunctional aldehyde–alcohol dehydrogenase are essential for energy metabolism under oxidative stress in Entamoeba histolytica pdf
Báo cáo khoa học: Pyruvate:ferredoxin oxidoreductase and bifunctional aldehyde–alcohol dehydrogenase are essential for energy metabolism under oxidative stress in Entamoeba histolytica pdf
... FEBS 3395 Pyruvate:ferredoxin oxidoreductase and bifunctional aldehyde–alcohol dehydrogenase are essential for energy metabolism under oxidative stress in Entamoeba histolytica Erika Pineda 1 , ... 2010) doi:10.1111/j.1742-4658.2010.07743.x The in vitro Entamoeba histolytica pyruvate:ferredoxin oxidoreductase (EhPFOR) kinetic properties and the ef...
Ngày tải lên: 15/03/2014, 23:20
Báo cáo khoa học: ATP-binding domain of heat shock protein 70 is essential for its effects on the inhibition of the release of the second mitochondria-derived activator of caspase and apoptosis in C2C12 cells potx
... direct interac- tion between HSP70 and Smac proteins, and the ATP-binding domain of HSP70, rather than the pep- tide-binding domain, was essential for this specific function of the protein. Recent ... that the ATP-binding domain of HSP70 is essential for its anti-apoptotic role. For example, deletional analysis demonstrated that the ATP-binding domain is essential for inhibit...
Ngày tải lên: 16/03/2014, 01:20
Báo cáo khoa học: Perturbation of folding and reassociation of lactate dehydrogenase by proline and trimethylamine oxide potx
... were incubated on ice for 60 min. All incubations, for both inactivation and reactivation, were performed in polypropylene tubes. Reactivation Renaturation following unfolding in GdnHCl was initiated by ... Each of the lines shown for proline represents a single experiment, the points for the line for controls reflect five independent determinations. Ó FEBS 2003 Perturbation of...
Ngày tải lên: 23/03/2014, 15:21
Báo cáo khoa học: A hydrophobic segment within the C-terminal domain is essential for both client-binding and dimer formation of the HSP90-family molecular chaperone pptx
... identification of the minimal region of the C-terminal domain for the client binding. Bearing in mind the fact that the 35-amino-acid residues corresponding to the C-terminus of HSP90 are deleted in HtpG, ... domain and the C-terminal domain. Similarly, the C-terminal 326 amino acids of barley GRP94 [22] and 200 amino acids of canine GRP94 [27] are sufficient for the dimer forma...
Ngày tải lên: 23/03/2014, 20:22
Báo cáo khoa học: "Combining Lexical, Syntactic, and Semantic Features with Maximum Entropy Models for Extracting Relations" pptx
... LDC into separate training and development sets. The training set contained around 300K words, and 9752 instances of relations and the development set con- tained around 46K words, and 1679 instances ... 2004) for more details of our men- tion detection and mention chaining modules. In the next section, we describe our extraction system. We present results in section 3, and...
Ngày tải lên: 31/03/2014, 03:20
Báo cáo khoa học: Reduction of S-nitrosoglutathione by human alcohol dehydrogenase 3 is an irreversible reaction as analysed by electrospray mass spectrometry pptx
... double focussing sectors of the instrument (MS1) focussing them into an inter- mediate collision cell containing Xe and orthogonally accelerating undissociated precursors and fragment ions into the ... [31]. For HMGSH, an exact positioning in the active site is essential for efficient catalysis. The substrate binding is accomplished in part by a charge interaction between Arg115...
Ngày tải lên: 31/03/2014, 07:20
Tài liệu Báo cáo khoa học: Pyruvate reduces DNA damage during hypoxia and after reoxygenation in hepatocellular carcinoma cells pptx
... reoxygenation but is ineffective at maintaining glutathione levels during hypoxia Glutathione is one of the main antioxidant compounds in the cell, and it is also essential for DNA synthesis and repair ... protective effects against hypoxia and reoxygenation. This is mainly ascribed to its ability to maintain redox status [17], intervening in the DNA repair system [18–20] and...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx
... mitogen-activated protein kinase kinase, in vitro and in vivo: analysis of active mutants expressed in E. coli and generation of the active form in stress response in seedlings. Plant J 29, 637–647. 40 ... of the mitogen-activated protein kinases (MAP- Ks), MPK3 and MPK6, in response to oxidative stress. In addition, the serine ⁄ threonine protein kinase Pto-interacti...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx
... promoting an increase in proopiomelanocortin and cocaine and amphetamine regulated transcript. Taken together, these findings provide a compelling argument for the role for malo- nyl-CoA in regulating ... as other sites, are known to reach the CNS to effect changes in feeding behavior and energy expenditure. Thus, insulin, leptin and ghrelin, as well as other hormones ⁄ c...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Báo cáo khoa học: X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate docx
... ATP-binding pocket. Pantoate binding to the ATP-binding site induced large changes in structure, mainly for backbone and side chain atoms of residues in the ATP binding HXGH(34–37) motif. Sequence-specific ... panto- ate-binding and ATP-binding sites of PS [11]. ATP caused additional changes in the spectrum, particularly for those residues that lie in the ATP-binding pocket. In...
Ngày tải lên: 16/02/2014, 09:20