Báo cáo khoa học: Delineation of the roles of FadD22, FadD26 and FadD29 in the biosynthesis of phthiocerol dimycocerosates and related compounds in Mycobacterium tuberculosis pptx

... representation of the roles of the FadD proteins encoded by the DIM + PGL locus in the biosynthesis of DIMs and related compounds in Mycobacterium tuberculosis. The role of the activation enzymes FadD22, FadD26 ... knowledge of the bio- synthesis of DIMs and PGLs, the in vivo functions of these FadD proteins in this pathway remain to be...

Ngày tải lên: 15/03/2014, 11:20

... shown). The basic cluster of amino acids in the binding groove of 14-3-3, including amino acids Lys-49, Arg- 56, Lys-120 and Arg-127, in an otherwise acidic mole- cule, are important for the interaction ... for phosphorylation-independent binding The interaction between 14-3-3 and ExoS is important for the ADP ribosylation activity of ExoS and even more intriguingly,...

Ngày tải lên: 19/02/2014, 08:20

... of the input and the eluate of the chromatography were resolved by Tricine ⁄ SDS ⁄ PAGE and then analyzed by Coo- massie Brilliant Blue staining (left) and western blotting (right). Lane 1: input ... to those of bombyxin and insulin, which are of the order of 100 pm [23,24]. The very high titer of 8K-BLP may be due to a remarkably high level of gene expression...

Ngày tải lên: 18/02/2014, 13:20

... that the most characteristic signatures in the sequences are present in both proteins, tyrosinases and catechol oxidases; these include the six histidine resi- dues involved in the binding of a ... browning of fruits and vegetables, and morphogenesis and fruiting body formation in fungi. All of these processes involve melanin formation. In the bacterial kingd...

Ngày tải lên: 19/02/2014, 07:20

... mechanism of the deamination reaction and the subsequent metabolism, including the deamination step. The product formed from 4-amino-3-hydroxybenzoic acid by the action of purified 4-amino-3-hydroxybenzoate 2,3-dioxygenase ... of the purified enzyme at 266 nm. The typical protein absorption p eak of 2 80 nm shifts to 265 nm if the protein contains a flavin-type cofac t...

Ngày tải lên: 19/02/2014, 16:20

... representation is defined as a mapping between elements of the set of substrings of the string and elements of the set of subtrees of the tree : such a relation is called a string- tree correspondence. ... substrings of the related sentence The characteristic of the linguistic approach is the design of the multilevel structures, while the grammar f...

Ngày tải lên: 22/02/2014, 10:20

... proceed for 10 min, and the fluorescence was then measured at room tem- perature. In uence of interference The in uence of the main constituents of plasma on the determination of 2.00 · 10 )6 molÆL )1 GSH ... metallobridged bis(b-CD)s 2 The in uence of the concentration of 2 on fluorescence intensity is shown in Fig. 4. As can be seen, as the concentration of...

Ngày tải lên: 07/03/2014, 05:20

... contacts the C-terminus of Hsp90 [48], its binding also displaces bound GA, indicating that there is also an interaction of Sti1p with the ADP/ATP binding site of the chaperone [33]. The increased ... ADP/ATP binding site, thereby inhibiting the ATP binding step of the Hsp90 chaperone cycle [6–9]. Interest in Hsp90-targeting drugs as possible anticancer agents was trigge...

Ngày tải lên: 07/03/2014, 21:20

... for the logistic regression model. More information about the origin and smoothing of the probabilities is given in Section 6. 4.2 Measuring the tense difficulty Having considered the complexity of ... 1), α 1 and β 1 = 0. Thus, when looking for the proba- bility of a text belonging to the baseline level, it is easy to compute the numerator, since exp(0) = 1. The...

Ngày tải lên: 08/03/2014, 21:20

... transactivation domain. The DNA-bind- ing domain is responsible for DNA binding specificity and dimerization, and the ligand-binding domain is responsible for binding of the ligand and associated induced ... splicing of the E2-responsive gene, oxytocin [90]. NRs also interact with the SR (serine- and arginine-rich proteins) family of splicing factors. CAPER, a SR-like p...

Ngày tải lên: 16/02/2014, 14:20