... MINIREVIEW Hepatocyte growth factor activator (HGFA) : molecular structure and interactions with HGFA inhibitor-1 (HAI-1) Charles Eigenbrot1,2, Rajkumar Ganesan3 and Daniel Kirchhofer31 ... of HGFA, which is limited to the two known macromolecular substratespro -hepatocyte growth factor and pro-macrophage-stimulating protein.AbbreviationsEGF, epidermal growth factor; HAI, hepatocyte ... hepatocyte growth factor activator inhibitor; HGFA, hepatocyte growth factor activator; KD1, Kunitzdomain-1; KD2, Kunitz domain-2; LDL, low-density lipoprotein; PDB, Protein Data Bank; pro-HGF, pro-hepatocyte...