Báo cáo khoa học: Highly site-selective stability increases by glycosylation of dihydrofolate reductase ppt
Báo cáo khoa học: Highly site-selective stability increases by glycosylation of dihydrofolate reductase ppt
... Highly site-selective stability increases by glycosylation of dihydrofolate reductase Lai-Hock Tey 1 , E. Joel Loveridge 1 , Richard S. ... Increased thermal stability of site-selectively glycosylated dihydrofolate reductase. ChemBioChem 6, 1338–1340. 15 Baek WO & Vijayalakshmi MA (1997) Effect of chemi- cal glycosylation of Rnase A ... case of dihy- drof...
Ngày tải lên: 15/03/2014, 11:20
Tài liệu Báo cáo khoa học: "Learning the Fine-Grained Information Status of Discourse Entities" pptx
... knowledge of IS is identity coreference: since new entities by definition have not been previously referred to, an NP marked as new does not need to be resolved, thereby improving the precision of a ... usefulness of IS in NLP tasks, there has been little work on learning the IS of discourse entities. To investigate the plausibility of learning IS, Nissim et al. (2004) annotate a s...
Ngày tải lên: 22/02/2014, 03:20
Báo cáo khoa học: Amyloid oligomers: diffuse oligomer-based transmission of yeast prions ppt
... caused by the amyloid-like aggregates of Sup35 [13]. The propagation of [PSI + ]is strictly dependent on the presence of an appropriate amount of Hsp104 [19]. Impairment of Hsp104 func- tion, by ... phenomena of protein-based inheritance. The behavior of diffuse oligomers of Sup35 in the GuHCl-treated [PSI + ] cells can be explained by an impairment of the division pha...
Ngày tải lên: 06/03/2014, 09:22
Tài liệu Báo cáo khoa học: P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity pptx
... Vernier P & Sidhu A (2003) Modulation of dopamine transporter function by a-synuclein is altered by impairment of cell adhesion and by induction of oxidative stress. FASEB J 17, 2151–2153. 11 ... membrane expression of DAT A potential effect of p25a on DAT function was addressed by expressing DAT alone and in the presence of p25a in HEK-293-MSR cells. To validate the s...
Ngày tải lên: 14/02/2014, 21:20
Tài liệu Báo cáo khoa học: The conformational stability of the Streptomyces coelicolor histidine-phosphocarrier protein Characterization of cold denaturation and urea–protein interactions doc
... Conformational stability of HPr of S. coelicolor (Eur. J. Biochem. 271) 2177 Validation of the LEM in analysis of scHPr data The use of LEM in several proteins has resulted in the complete determination of ... facilitated by the presence of denaturants (chemicals or pH), as denaturants raise the cold-transition temperature and depress the freezing point of water [1,8,9,22,...
Ngày tải lên: 19/02/2014, 12:20
Báo cáo khoa học: Hyperthermophilic enzymes ) stability, activity and implementation strategies for high temperature applications pot
... C-W, Shih P-C, Lin T-S & Mou C-Y (2005) Enhancing stability and oxidation activity of cytochrome c by immobilization in the nanchannels of mesoporous aluminosilicates. J Phys Chem B 109, 12277–12286. 56 ... Sheardown H & Brash JL (2005) Pro- tein resistance of surfaces prepared by sorption of end- thiolated poly(ethylene glycol) to gold: effect of surface chain density...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Acidic extracellular pH increases calcium influx-triggered phospholipase D activity along with acidic sphingomyelinase activation to induce matrix metalloproteinase-9 expression in mouse metastatic melanoma pot
... identified as [ 3 H]-cer- amide by comigration of N-palmitoyl-d-erythro-sphingo- sine [C16:0 (palmitoyl) ceramide], were scrapped off and their radioactivities were counted by liquid scintillation counter. RT-PCR Total ... inhibitory action of docosahexaenoic acid. FEBS Lett 564, 177– 182. 37 Zeng L, An S & Goetzl EJ (1996) Regulation of expres- sion of matrix metalloproteinase...
Ngày tải lên: 07/03/2014, 09:20
Báo cáo khoa học: Local changes in the catalytic site of mammalian histidine decarboxylase can affect its global conformation and stability pptx
... center in addition to those established by the internal aldimine alone. From the shape of the a-FMH-treated protein spectra, stabilization of some a-helix by the cofactor adduct could be suspected ... the catalytic sites of HDC are also in the interface between monomers, we postulated the hypothesis that the observed high degree of rotation of the torsion angle v induced by th...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: " Medication errors: a prospective cohort study of hand-written and computerised physician order entry in the intensive care unit"
... remit of the local ethics committee. Prior to introduction of CPOE, local standards of prescribing existed specifying the tenets of good practice, including the avoid- ance of the use of abbreviations. An ... monitoring period, details of the total number of all prescribed drugs on each day were recorded. MEs were assessed by type and patient outcome. The type of error was...
Ngày tải lên: 25/10/2012, 10:39
Tài liệu Báo cáo khoa học: a-enolase: a promising therapeutic and diagnostic tumor target ppt
... an early stage of tumorigenesis, as illustrated by the detection of high titers of autoantibodies in patients with early-stage cancer [64], and correlates with the progression of malignant transformation ... contact activation of fibroblasts increases the expression of matrix metalloproteinases. Ann Med 38, 212–220. 59 Smith R, Xue A, Gill A, Scarlett C, Saxby A, Clarkson A &am...
Ngày tải lên: 14/02/2014, 19:20